abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	MA	1 - 2	2
HFR1	DVQLVESGGGLVQAGGSLRVSCAASGRTFS	3 - 32	30
CDR-H1	SYSMG	33 - 37	5
HFR2	WFRQAPGKEREFVA	38 - 51	14
CDR-H2	AISRSDNSTYYADSVKG	52 - 68	17
HFR3	RFTISRDSAKNTVYLQMNSLKPEDTAVYYCAA	69 - 100	32
CDR-H3	TPYGSRYYLRELREYDY	101 - 117	17
HFR4	WGQGTQVTVSS	118 - 128	11
Tail	HHHHHH	128 - 134	6
			134

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLVESGGGLVQAGGSLRVSCAAS-----	3 - 27	25
	AbM	DVQLVESGGGLVQAGGSLRVSCAAS-----	3 - 27	25
	Kabat	DVQLVESGGGLVQAGGSLRVSCAASGRTFS	3 - 32	30
	Contact	DVQLVESGGGLVQAGGSLRVSCAASGRTF-	3 - 31	29
	IMGT	DVQLVESGGGLVQAGGSLRVSCAAS-----	3 - 27	25
CDR-H1	Chothia	GRTFSSY---	28 - 34	7
	AbM	GRTFSSYSMG	28 - 37	10
	Kabat	-----SYSMG	33 - 37	5
	Contact	----SSYSMG	32 - 37	6
	IMGT	GRTFSSYS--	28 - 35	8
HFR2	Chothia	SMGWFRQAPGKEREFVAAI	35 - 53	19
	AbM	---WFRQAPGKEREFVA--	38 - 51	14
	Kabat	---WFRQAPGKEREFVA--	38 - 51	14
	Contact	---WFRQAPGKERE-----	38 - 48	11
	IMGT	-MGWFRQAPGKEREFVAA-	36 - 52	17
CDR-H2	Chothia	-----SRSDNS---------	54 - 59	6
	AbM	---AISRSDNSTY-------	52 - 61	10
	Kabat	---AISRSDNSTYYADSVKG	52 - 68	17
	Contact	FVAAISRSDNSTY-------	49 - 61	13
	IMGT	----ISRSDNST--------	53 - 60	8
HFR3	Chothia	TYYADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYCAA	60 - 100	41
	AbM	--YADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYCAA	62 - 100	39
	Kabat	---------RFTISRDSAKNTVYLQMNSLKPEDTAVYYCAA	69 - 100	32
	Contact	--YADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYC--	62 - 98	37
	IMGT	-YYADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYC--	61 - 98	38
CDR-H3	Chothia	--TPYGSRYYLRELREYDY	101 - 117	17
	AbM	--TPYGSRYYLRELREYDY	101 - 117	17
	Kabat	--TPYGSRYYLRELREYDY	101 - 117	17
	Contact	AATPYGSRYYLRELREYD-	99 - 116	18
	IMGT	AATPYGSRYYLRELREYDY	99 - 117	19
HFR4	Chothia	-WGQGTQVTVSS	118 - 128	11
	AbM	-WGQGTQVTVSS	118 - 128	11
	Kabat	-WGQGTQVTVSS	118 - 128	11
	Contact	YWGQGTQVTVSS	117 - 128	12
	IMGT	-WGQGTQVTVSS	118 - 128	11

Accession & Annotations

Accession	5lz0_B
Source	PDB 5lz0 Submitted 29-SEP-2016 Updated 06-SEP-2017
Name	LLAMA NANOBODY PORM_01
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5lz0_A 6ey0_E 6ey0_G 6ey0_H
References	DUHOO Y., ROCHE J., TRINH N., DESMYTER A., GAUBERT A., KELLENBERGER C., CAMBILLAU C., ROUSSEL A., LEONE P. 'CAMELID NANOBODIES USED AS CRYSTALLIZATION CHAPERONES FOR DIFFERENT CONSTRUCTS OF PORM, A COMPONENT OF THE TYPE IX SECRETION SYSTEM FROM PORPHYROMONAS GINGIVALIS.' ACTA CRYSTALLOGR F STRUCT V. 73 286 2017 BIOL COMMUN ESSN 2053-230X

Tools

Sequences

Amino Acid Sequence:

MADVQLVESGGGLVQAGGSLRVSCAASGRTFSSYSMGWFRQAPGKEREFVAAISRSDNST
YYADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYCAATPYGSRYYLRELREYDYWGQ
GTQVTVSSHHHHHH