abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	MKYLLPTAAAGLLLLAAQPAMA	1 - 22	22
HFR1	QVQLVESGGGSVQAGGSLRLSCAASGNTDS	23 - 52	30
CDR-H1	SYYMG	53 - 57	5
HFR2	WFRQGPGKEREGVA	58 - 71	14
CDR-H2	SIYIRAGIPYYTDSVKG	72 - 88	17
HFR3	RFTISQDNAKNTIYLQMNSLKPEDTAMYFCAG	89 - 120	32
CDR-H3	SVRTTIQPFKGNYYNY	121 - 136	16
HFR4	WGRGTQVTVSS	137 - 147	11
Tail	HHHHHH	147 - 153	6
			153

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLVESGGGSVQAGGSLRLSCAAS-----	23 - 47	25
	AbM	QVQLVESGGGSVQAGGSLRLSCAAS-----	23 - 47	25
	Kabat	QVQLVESGGGSVQAGGSLRLSCAASGNTDS	23 - 52	30
	Contact	QVQLVESGGGSVQAGGSLRLSCAASGNTD-	23 - 51	29
	IMGT	QVQLVESGGGSVQAGGSLRLSCAAS-----	23 - 47	25
CDR-H1	Chothia	GNTDSSY---	48 - 54	7
	AbM	GNTDSSYYMG	48 - 57	10
	Kabat	-----SYYMG	53 - 57	5
	Contact	----SSYYMG	52 - 57	6
	IMGT	GNTDSSYY--	48 - 55	8
HFR2	Chothia	YMGWFRQGPGKEREGVASI	55 - 73	19
	AbM	---WFRQGPGKEREGVA--	58 - 71	14
	Kabat	---WFRQGPGKEREGVA--	58 - 71	14
	Contact	---WFRQGPGKERE-----	58 - 68	11
	IMGT	-MGWFRQGPGKEREGVAS-	56 - 72	17
CDR-H2	Chothia	-----YIRAGI---------	74 - 79	6
	AbM	---SIYIRAGIPY-------	72 - 81	10
	Kabat	---SIYIRAGIPYYTDSVKG	72 - 88	17
	Contact	GVASIYIRAGIPY-------	69 - 81	13
	IMGT	----IYIRAGIP--------	73 - 80	8
HFR3	Chothia	PYYTDSVKGRFTISQDNAKNTIYLQMNSLKPEDTAMYFCAG	80 - 120	41
	AbM	--YTDSVKGRFTISQDNAKNTIYLQMNSLKPEDTAMYFCAG	82 - 120	39
	Kabat	---------RFTISQDNAKNTIYLQMNSLKPEDTAMYFCAG	89 - 120	32
	Contact	--YTDSVKGRFTISQDNAKNTIYLQMNSLKPEDTAMYFC--	82 - 118	37
	IMGT	-YYTDSVKGRFTISQDNAKNTIYLQMNSLKPEDTAMYFC--	81 - 118	38
CDR-H3	Chothia	--SVRTTIQPFKGNYYNY	121 - 136	16
	AbM	--SVRTTIQPFKGNYYNY	121 - 136	16
	Kabat	--SVRTTIQPFKGNYYNY	121 - 136	16
	Contact	AGSVRTTIQPFKGNYYN-	119 - 135	17
	IMGT	AGSVRTTIQPFKGNYYNY	119 - 136	18
HFR4	Chothia	-WGRGTQVTVSS	137 - 147	11
	AbM	-WGRGTQVTVSS	137 - 147	11
	Kabat	-WGRGTQVTVSS	137 - 147	11
	Contact	YWGRGTQVTVSS	136 - 147	12
	IMGT	-WGRGTQVTVSS	137 - 147	11

Accession & Annotations

Accession	5mp2_D
Source	PDB 5mp2 Submitted 15-DEC-2016 Updated 13-DEC-2017
Name	XCPQN012 IN COMPLEX WITH VHH04
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5mp2_C
References	DOUZI B., TRINH T., MICHEL-SOUZY S., DESMYTER A., BALL G., BARBIER P., KOSTA A., DURAND E., FOREST T., CAMBILLAU C., ROUSSEL A., VOULHOUX R. 'UNRAVELING THE SELF-ASSEMBLY OF THE PSEUDOMONAS AERUGINOSA XCPQ SECRETIN PERIPLASMIC DOMAIN PROVIDES NEW MOLECULAR INSIGHTS INTO TYPE II SECRETION SYSTEM SECRETON ARCHITECTURE AND DYNAMICS.' MBIO V. 8 2017 ESSN 2150-7511

Tools

Sequences

Amino Acid Sequence:

MKYLLPTAAAGLLLLAAQPAMAQVQLVESGGGSVQAGGSLRLSCAASGNTDSSYYMGWFR
QGPGKEREGVASIYIRAGIPYYTDSVKGRFTISQDNAKNTIYLQMNSLKPEDTAMYFCAG
SVRTTIQPFKGNYYNYWGRGTQVTVSSHHHHHH

Data Source:

Alignment settings:

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