abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLVESGGGLVQPGGSLRLSCAASGIMLG	1 - 30	30
CDR-H1	YFTMA	31 - 35	5
HFR2	WYRQAPGKQRELVA	36 - 49	14
CDR-H2	TEISGGSANYADAVKG	50 - 65	16
HFR3	RFTISRDNARSTVYLQMNSLKPEDTAVYYCDA	66 - 97	32
CDR-H3	RIWRGTVYDNI	98 - 108	11
HFR4	SGPGTQVTVSS	109 - 119	11
Tail	HHHHHH	119 - 125	6
			125

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLVESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLVESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLVESGGGLVQPGGSLRLSCAASGIMLG	1 - 30	30
	Contact	QVQLVESGGGLVQPGGSLRLSCAASGIML-	1 - 29	29
	IMGT	QVQLVESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GIMLGYF---	26 - 32	7
	AbM	GIMLGYFTMA	26 - 35	10
	Kabat	-----YFTMA	31 - 35	5
	Contact	----GYFTMA	30 - 35	6
	IMGT	GIMLGYFT--	26 - 33	8
HFR2	Chothia	TMAWYRQAPGKQRELVATE	33 - 51	19
	AbM	---WYRQAPGKQRELVA--	36 - 49	14
	Kabat	---WYRQAPGKQRELVA--	36 - 49	14
	Contact	---WYRQAPGKQRE-----	36 - 46	11
	IMGT	-MAWYRQAPGKQRELVAT-	34 - 50	17
CDR-H2	Chothia	-----ISGGS---------	52 - 56	5
	AbM	---TEISGGSAN-------	50 - 58	9
	Kabat	---TEISGGSANYADAVKG	50 - 65	16
	Contact	LVATEISGGSAN-------	47 - 58	12
	IMGT	----EISGGSA--------	51 - 57	7
HFR3	Chothia	ANYADAVKGRFTISRDNARSTVYLQMNSLKPEDTAVYYCDA	57 - 97	41
	AbM	--YADAVKGRFTISRDNARSTVYLQMNSLKPEDTAVYYCDA	59 - 97	39
	Kabat	---------RFTISRDNARSTVYLQMNSLKPEDTAVYYCDA	66 - 97	32
	Contact	--YADAVKGRFTISRDNARSTVYLQMNSLKPEDTAVYYC--	59 - 95	37
	IMGT	-NYADAVKGRFTISRDNARSTVYLQMNSLKPEDTAVYYC--	58 - 95	38
CDR-H3	Chothia	--RIWRGTVYDNI	98 - 108	11
	AbM	--RIWRGTVYDNI	98 - 108	11
	Kabat	--RIWRGTVYDNI	98 - 108	11
	Contact	DARIWRGTVYDN-	96 - 107	12
	IMGT	DARIWRGTVYDNI	96 - 108	13
HFR4	Chothia	-SGPGTQVTVSS	109 - 119	11
	AbM	-SGPGTQVTVSS	109 - 119	11
	Kabat	-SGPGTQVTVSS	109 - 119	11
	Contact	ISGPGTQVTVSS	108 - 119	12
	IMGT	-SGPGTQVTVSS	109 - 119	11

Accession & Annotations

Accession	5mwn_N
Source	PDB 5mwn Submitted 18-JAN-2017 Updated 06-SEP-2017
Name	STRUCTURE OF THE EAEC T6SS COMPONENT TSSK N-TERMINAL DOMAIN IN COMPLEX WITH LLAMA NANOBODIES NBK18 AND NBK27
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	NGUYEN S., LOGGER L., SPINELLI S., LEGRAND P., HUYEN PHAM T., NHUNG TRINH T., CHERRAK Y., ZOUED A., DESMYTER A., DURAND E., ROUSSEL A., KELLENBERGER C., CASCALES E., CAMBILLAU C. 'TYPE VI SECRETION TSSK BASEPLATE PROTEIN EXHIBITS STRUCTURAL SIMILARITY WITH PHAGE RECEPTOR-BINDING PROTEINS AND EVOLVED TO BIND THE MEMBRANE COMPLEX.' NAT MICROBIOL V. 2 17103 2017 ESSN 2058-5276

Tools

Sequences

Amino Acid Sequence:

QVQLVESGGGLVQPGGSLRLSCAASGIMLGYFTMAWYRQAPGKQRELVATEISGGSANYA
DAVKGRFTISRDNARSTVYLQMNSLKPEDTAVYYCDARIWRGTVYDNISGPGTQVTVSSH
HHHHH