abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQPGGSLRLSCAASETALT	1 - 30	30
CDR-H1	YYAIG	31 - 35	5
HFR2	WFRQAPGKEREGVS	36 - 49	14
CDR-H2	CISRINSGSGARTDYADSVKG	50 - 70	21
HFR3	RFTISRDDAKNTVTLQMNSLEPEDTARYYCAL	71 - 102	32
CDR-H3	DTTDRYDSANGRYYCTISSDTYDY	103 - 126	24
HFR4	WGQGTQVTVSS	127 - 137	11
Tail	HHHHHH	137 - 143	6
			143

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQPGGSLRLSCAASETALT	1 - 30	30
	Contact	QVQLQESGGGLVQPGGSLRLSCAASETAL-	1 - 29	29
	IMGT	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	ETALTYY---	26 - 32	7
	AbM	ETALTYYAIG	26 - 35	10
	Kabat	-----YYAIG	31 - 35	5
	Contact	----TYYAIG	30 - 35	6
	IMGT	ETALTYYA--	26 - 33	8
HFR2	Chothia	AIGWFRQAPGKEREGVSCI	33 - 51	19
	AbM	---WFRQAPGKEREGVS--	36 - 49	14
	Kabat	---WFRQAPGKEREGVS--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-IGWFRQAPGKEREGVSC-	34 - 50	17
CDR-H2	Chothia	-----SRINSGSGAR---------	52 - 61	10
	AbM	---CISRINSGSGARTD-------	50 - 63	14
	Kabat	---CISRINSGSGARTDYADSVKG	50 - 70	21
	Contact	GVSCISRINSGSGARTD-------	47 - 63	17
	IMGT	----ISRINSGSGART--------	51 - 62	12
HFR3	Chothia	TDYADSVKGRFTISRDDAKNTVTLQMNSLEPEDTARYYCAL	62 - 102	41
	AbM	--YADSVKGRFTISRDDAKNTVTLQMNSLEPEDTARYYCAL	64 - 102	39
	Kabat	---------RFTISRDDAKNTVTLQMNSLEPEDTARYYCAL	71 - 102	32
	Contact	--YADSVKGRFTISRDDAKNTVTLQMNSLEPEDTARYYC--	64 - 100	37
	IMGT	-DYADSVKGRFTISRDDAKNTVTLQMNSLEPEDTARYYC--	63 - 100	38
CDR-H3	Chothia	--DTTDRYDSANGRYYCTISSDTYDY	103 - 126	24
	AbM	--DTTDRYDSANGRYYCTISSDTYDY	103 - 126	24
	Kabat	--DTTDRYDSANGRYYCTISSDTYDY	103 - 126	24
	Contact	ALDTTDRYDSANGRYYCTISSDTYD-	101 - 125	25
	IMGT	ALDTTDRYDSANGRYYCTISSDTYDY	101 - 126	26
HFR4	Chothia	-WGQGTQVTVSS	127 - 137	11
	AbM	-WGQGTQVTVSS	127 - 137	11
	Kabat	-WGQGTQVTVSS	127 - 137	11
	Contact	YWGQGTQVTVSS	126 - 137	12
	IMGT	-WGQGTQVTVSS	127 - 137	11

Accession & Annotations

Accession	5o0w_H
Source	PDB 5o0w Submitted 17-MAY-2017 Updated 27-SEP-2017
Name	CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN NB474 AND TRYPANOSOMA CONGOLENSE FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE
Organism	Vicugna pacos
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5o0w_E 5o0w_F 5o0w_G
References	PINTO J., ODONGO S., LEE F., GASPARIUNAITE V., MUYLDERMANS S., MAGEZ S., STERCKX G. 'STRUCTURAL BASIS FOR THE HIGH SPECIFICITY OF A TRYPANOSOMA CONGOLENSE IMMUNOASSAY TARGETING GLYCOSOMAL ALDOLASE.' PLOS NEGL TROP DIS V. 11 05932 2017 ESSN 1935-2735

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQPGGSLRLSCAASETALTYYAIGWFRQAPGKEREGVSCISRINSGSGA
RTDYADSVKGRFTISRDDAKNTVTLQMNSLEPEDTARYYCALDTTDRYDSANGRYYCTIS
SDTYDYWGQGTQVTVSSHHHHHH