abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQPGGSLRLSCAASGTIFS	1 - 30	30
CDR-H1	RNIMG	31 - 35	5
HFR2	WYRQAPGKERELVA	36 - 49	14
CDR-H2	SIYSDRSTWYAESVEG	50 - 65	16
HFR3	RFTISRDNVKNTLYLQMNSLKPEDTAMYYCRD	66 - 97	32
CDR-H3	RTLGS	98 - 102	5
HFR4	WGQGTQVTVSS	103 - 113	11
Tail	HHHHHH	113 - 119	6
			119

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQPGGSLRLSCAASGTIFS	1 - 30	30
	Contact	QVQLQESGGGLVQPGGSLRLSCAASGTIF-	1 - 29	29
	IMGT	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GTIFSRN---	26 - 32	7
	AbM	GTIFSRNIMG	26 - 35	10
	Kabat	-----RNIMG	31 - 35	5
	Contact	----SRNIMG	30 - 35	6
	IMGT	GTIFSRNI--	26 - 33	8
HFR2	Chothia	IMGWYRQAPGKERELVASI	33 - 51	19
	AbM	---WYRQAPGKERELVA--	36 - 49	14
	Kabat	---WYRQAPGKERELVA--	36 - 49	14
	Contact	---WYRQAPGKERE-----	36 - 46	11
	IMGT	-MGWYRQAPGKERELVAS-	34 - 50	17
CDR-H2	Chothia	-----YSDRS---------	52 - 56	5
	AbM	---SIYSDRSTW-------	50 - 58	9
	Kabat	---SIYSDRSTWYAESVEG	50 - 65	16
	Contact	LVASIYSDRSTW-------	47 - 58	12
	IMGT	----IYSDRST--------	51 - 57	7
HFR3	Chothia	TWYAESVEGRFTISRDNVKNTLYLQMNSLKPEDTAMYYCRD	57 - 97	41
	AbM	--YAESVEGRFTISRDNVKNTLYLQMNSLKPEDTAMYYCRD	59 - 97	39
	Kabat	---------RFTISRDNVKNTLYLQMNSLKPEDTAMYYCRD	66 - 97	32
	Contact	--YAESVEGRFTISRDNVKNTLYLQMNSLKPEDTAMYYC--	59 - 95	37
	IMGT	-WYAESVEGRFTISRDNVKNTLYLQMNSLKPEDTAMYYC--	58 - 95	38
CDR-H3	Chothia	--RTLGS	98 - 102	5
	AbM	--RTLGS	98 - 102	5
	Kabat	--RTLGS	98 - 102	5
	Contact	RDRTLG-	96 - 101	6
	IMGT	RDRTLGS	96 - 102	7
HFR4	Chothia	-WGQGTQVTVSS	103 - 113	11
	AbM	-WGQGTQVTVSS	103 - 113	11
	Kabat	-WGQGTQVTVSS	103 - 113	11
	Contact	SWGQGTQVTVSS	102 - 113	12
	IMGT	-WGQGTQVTVSS	103 - 113	11

Accession & Annotations

Accession	5omn_C
Source	PDB 5omn Submitted 01-AUG-2017 Updated 15-NOV-2017
Name	GII.10 VIETNAM 026 PROTRUDING DOMAIN IN COMPLEX WITH NANOBODY NANO-27
Organism	Vicugna pacos
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	KOROMYSLOVA D., HANSMAN S. 'NANOBODIES TARGETING NOROVIRUS CAPSID REVEAL FUNCTIONAL EPITOPES AND POTENTIAL MECHANISMS OF NEUTRALIZATION.' PLOS PATHOG. V. 13 06636 2017 ESSN 1553-7374

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQPGGSLRLSCAASGTIFSRNIMGWYRQAPGKERELVASIYSDRSTWYA
ESVEGRFTISRDNVKNTLYLQMNSLKPEDTAMYYCRDRTLGSWGQGTQVTVSSHHHHHH