abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGDSVQAGGSLRLACAASASGYT	1 - 30	30
CDR-H1	ESVKWMG	31 - 37	7
HFR2	WFRQAPGQEREGVA	38 - 51	14
CDR-H2	VISIPGGSTYYDDDVKG	52 - 68	17
HFR3	RFTISQDNAKNTVYPQMNSLKPEDTAMYYCAA	69 - 100	32
CDR-H3	RNAGGRFRAWAGGGDNY	101 - 117	17
HFR4	WGQGTQVTVSS	118 - 128	11
			128

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGDSVQAGGSLRLACAAS-----	1 - 25	25
	AbM	QVQLQESGGDSVQAGGSLRLACAAS-----	1 - 25	25
	Kabat	QVQLQESGGDSVQAGGSLRLACAASASGYT	1 - 30	30
	Contact	QVQLQESGGDSVQAGGSLRLACAASASGY-	1 - 29	29
	IMGT	QVQLQESGGDSVQAGGSLRLACAAS-----	1 - 25	25
CDR-H1	Chothia	ASGYTESVK---	26 - 34	9
	AbM	ASGYTESVKWMG	26 - 37	12
	Kabat	-----ESVKWMG	31 - 37	7
	Contact	----TESVKWMG	30 - 37	8
	IMGT	ASGYTESVKW--	26 - 35	10
HFR2	Chothia	WMGWFRQAPGQEREGVAVI	35 - 53	19
	AbM	---WFRQAPGQEREGVA--	38 - 51	14
	Kabat	---WFRQAPGQEREGVA--	38 - 51	14
	Contact	---WFRQAPGQERE-----	38 - 48	11
	IMGT	-MGWFRQAPGQEREGVAV-	36 - 52	17
CDR-H2	Chothia	-----SIPGGS---------	54 - 59	6
	AbM	---VISIPGGSTY-------	52 - 61	10
	Kabat	---VISIPGGSTYYDDDVKG	52 - 68	17
	Contact	GVAVISIPGGSTY-------	49 - 61	13
	IMGT	----ISIPGGST--------	53 - 60	8
HFR3	Chothia	TYYDDDVKGRFTISQDNAKNTVYPQMNSLKPEDTAMYYCAA	60 - 100	41
	AbM	--YDDDVKGRFTISQDNAKNTVYPQMNSLKPEDTAMYYCAA	62 - 100	39
	Kabat	---------RFTISQDNAKNTVYPQMNSLKPEDTAMYYCAA	69 - 100	32
	Contact	--YDDDVKGRFTISQDNAKNTVYPQMNSLKPEDTAMYYC--	62 - 98	37
	IMGT	-YYDDDVKGRFTISQDNAKNTVYPQMNSLKPEDTAMYYC--	61 - 98	38
CDR-H3	Chothia	--RNAGGRFRAWAGGGDNY	101 - 117	17
	AbM	--RNAGGRFRAWAGGGDNY	101 - 117	17
	Kabat	--RNAGGRFRAWAGGGDNY	101 - 117	17
	Contact	AARNAGGRFRAWAGGGDN-	99 - 116	18
	IMGT	AARNAGGRFRAWAGGGDNY	99 - 117	19
HFR4	Chothia	-WGQGTQVTVSS	118 - 128	11
	AbM	-WGQGTQVTVSS	118 - 128	11
	Kabat	-WGQGTQVTVSS	118 - 128	11
	Contact	YWGQGTQVTVSS	117 - 128	12
	IMGT	-WGQGTQVTVSS	118 - 128	11

Accession & Annotations

Accession	BAQ56198.1
Source	abYsis-EMBL-IG AB987658 Submitted 14-MAR-2015 Updated 14-MAR-2015
Name	immunoglobulin heavy chain variable region
Clone	DR-9p
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Jalili S., Hasannia S., Shahangian S.S., Mohamadi M., Arab S.S., Hasansajedi R., Shali A., Khajeh K. Submitted (02-SEP-2014) to the INSDC. Contact:Shirin Jalili Tarbiat Modares University, Biochemistry; Jalal Ale Ahmad Highway, P.O.Box, Tehran 14115-111, Iran Jalili S., Hasannia S., Shahangian S.S., Mohamadi M., Arab S.S., Hasansajedi R., Shali A., Khajeh K. 'Construction and screening of specific nanobadies for apoptosis-inducing epitope on the NTR-DR5 domain by phage display technique' Unpublished.

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGDSVQAGGSLRLACAASASGYTESVKWMGWFRQAPGQEREGVAVISIPGGST
YYDDDVKGRFTISQDNAKNTVYPQMNSLKPEDTAMYYCAARNAGGRFRAWAGGGDNYWGQ
GTQVTVSS

DNA Sequence:

caggtgcagctgcaggagtcggggggagactcggtgcaggctggagggtctctgagactc
gcctgtgcagcctcagcctctggatacaccgaaagtgtgaagtggatgggctggttccgc
caggctccagggcaggagcgcgagggggtcgcagttatttctattcctggtggtagtaca
tactatgacgacgacgtgaagggccgatttaccatctcccaagacaacgccaagaacacg
gtgtatccgcaaatgaacagtctgaaacctgaggacactgccatgtactattgcgcagcg
cgcaatgcgggggggcgttttcgggcttgggccggtggtggggataattattggggccag
gggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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