abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGGSLRLSCAASGRTFS	1 - 27	27
CDR-H1	SYAMG	28 - 32	5
HFR2	WFRQAPGKEREFVA	33 - 46	14
CDR-H2	AISWSGTITSYADSVKG	47 - 63	17
HFR3	RFTISRDNAKNMVYLQMNSLKPEDTAVYYCAA	64 - 95	32
CDR-H3	ALGYGSRHLDAYAY	96 - 109	14
HFR4	WGLGTQVT	110 - 117	8
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGGSLRLSCAASGRTFS	1 - 27	27
	Contact	LQESGGGLVQAGGSLRLSCAASGRTF-	1 - 26	26
	IMGT	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GRTFSSY---	23 - 29	7
	AbM	GRTFSSYAMG	23 - 32	10
	Kabat	-----SYAMG	28 - 32	5
	Contact	----SSYAMG	27 - 32	6
	IMGT	GRTFSSYA--	23 - 30	8
HFR2	Chothia	AMGWFRQAPGKEREFVAAI	30 - 48	19
	AbM	---WFRQAPGKEREFVA--	33 - 46	14
	Kabat	---WFRQAPGKEREFVA--	33 - 46	14
	Contact	---WFRQAPGKERE-----	33 - 43	11
	IMGT	-MGWFRQAPGKEREFVAA-	31 - 47	17
CDR-H2	Chothia	-----SWSGTI---------	49 - 54	6
	AbM	---AISWSGTITS-------	47 - 56	10
	Kabat	---AISWSGTITSYADSVKG	47 - 63	17
	Contact	FVAAISWSGTITS-------	44 - 56	13
	IMGT	----ISWSGTIT--------	48 - 55	8
HFR3	Chothia	TSYADSVKGRFTISRDNAKNMVYLQMNSLKPEDTAVYYCAA	55 - 95	41
	AbM	--YADSVKGRFTISRDNAKNMVYLQMNSLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISRDNAKNMVYLQMNSLKPEDTAVYYCAA	64 - 95	32
	Contact	--YADSVKGRFTISRDNAKNMVYLQMNSLKPEDTAVYYC--	57 - 93	37
	IMGT	-SYADSVKGRFTISRDNAKNMVYLQMNSLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--ALGYGSRHLDAYAY	96 - 109	14
	AbM	--ALGYGSRHLDAYAY	96 - 109	14
	Kabat	--ALGYGSRHLDAYAY	96 - 109	14
	Contact	AAALGYGSRHLDAYA-	94 - 108	15
	IMGT	AAALGYGSRHLDAYAY	94 - 109	16
HFR4	Chothia	-WGLGTQVT	110 - 117	8
	AbM	-WGLGTQVT	110 - 117	8
	Kabat	-WGLGTQVT	110 - 117	8
	Contact	YWGLGTQVT	109 - 117	9
	IMGT	-WGLGTQVT	110 - 117	8

Accession & Annotations

Accession	CAD22457.1
Source	abYsis-EMBL-IG AJ429744 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C1
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGGSLRLSCAASGRTFSSYAMGWFRQAPGKEREFVAAISWSGTITSYADS
VKGRFTISRDNAKNMVYLQMNSLKPEDTAVYYCAAALGYGSRHLDAYAYWGLGTQVT

DNA Sequence:

ctgcaggagtctgggggaggattggtgcaggctgggggctcgctgagactctcctgtgca
gcctctggacgcaccttcagtagttatgccatgggctggttccgccaggctcccgggaag
gagcgtgagtttgtagcagctattagctggagtggtacgatcacatcctatgcagactcc
gtgaagggccgattcaccatctccagagataatgccaagaacatggtgtatctgcaaatg
aacagcctgaaacctgaggacacggccgtctattactgtgcagctgcgttagggtacggt
agtagacacttggatgcgtatgcgtactggggcctggggacccaggtcacc

Data Source:

Alignment settings:

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