abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGGSLRLSCAASESYFS	1 - 27	27
CDR-H1	INRMG	28 - 32	5
HFR2	WYRQAPGNQRELVA	33 - 46	14
CDR-H2	SISSGGSTNYADSVKG	47 - 62	16
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYLCNV	63 - 94	32
CDR-H3	NAYHSGNLYTY	95 - 105	11
HFR4	WGQGTQVT	106 - 113	8
			113

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGGSLRLSCAASESYFS	1 - 27	27
	Contact	LQESGGGLVQAGGSLRLSCAASESYF-	1 - 26	26
	IMGT	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	ESYFSIN---	23 - 29	7
	AbM	ESYFSINRMG	23 - 32	10
	Kabat	-----INRMG	28 - 32	5
	Contact	----SINRMG	27 - 32	6
	IMGT	ESYFSINR--	23 - 30	8
HFR2	Chothia	RMGWYRQAPGNQRELVASI	30 - 48	19
	AbM	---WYRQAPGNQRELVA--	33 - 46	14
	Kabat	---WYRQAPGNQRELVA--	33 - 46	14
	Contact	---WYRQAPGNQRE-----	33 - 43	11
	IMGT	-MGWYRQAPGNQRELVAS-	31 - 47	17
CDR-H2	Chothia	-----SSGGS---------	49 - 53	5
	AbM	---SISSGGSTN-------	47 - 55	9
	Kabat	---SISSGGSTNYADSVKG	47 - 62	16
	Contact	LVASISSGGSTN-------	44 - 55	12
	IMGT	----ISSGGST--------	48 - 54	7
HFR3	Chothia	TNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYLCNV	54 - 94	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYLCNV	56 - 94	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYLCNV	63 - 94	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYLC--	56 - 92	37
	IMGT	-NYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYLC--	55 - 92	38
CDR-H3	Chothia	--NAYHSGNLYTY	95 - 105	11
	AbM	--NAYHSGNLYTY	95 - 105	11
	Kabat	--NAYHSGNLYTY	95 - 105	11
	Contact	NVNAYHSGNLYT-	93 - 104	12
	IMGT	NVNAYHSGNLYTY	93 - 105	13
HFR4	Chothia	-WGQGTQVT	106 - 113	8
	AbM	-WGQGTQVT	106 - 113	8
	Kabat	-WGQGTQVT	106 - 113	8
	Contact	YWGQGTQVT	105 - 113	9
	IMGT	-WGQGTQVT	106 - 113	8

Accession & Annotations

Accession	CAD22458.1
Source	abYsis-EMBL-IG AJ429745 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C5
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGGSLRLSCAASESYFSINRMGWYRQAPGNQRELVASISSGGSTNYADSV
KGRFTISRDNAKNTVYLQMNSLKPEDTAVYLCNVNAYHSGNLYTYWGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggcttggtgcaggctggggggtctctgagactctcctgtgca
gcctctgaaagctacttcagtatcaatcgcatgggctggtaccgccaggctccagggaac
cagcgcgagttggtcgcaagtattagtagtggtggtagtacaaactatgccgactccgtg
aagggccgattcaccatctccagagacaacgccaagaacacagtgtatctgcaaatgaac
agcctgaaacctgaggacacggccgtctatttgtgtaatgtaaatgcatatcacagtggt
aatttgtatacctactggggtcaggggacccaggtcacc

Data Source:

Alignment settings:

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