abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGGSLRLSCAASVSTFS	1 - 27	27
CDR-H1	INAMG	28 - 32	5
HFR2	WYRQAPGKQRELVA	33 - 46	14
CDR-H2	DISSGGGTNYADSVKG	47 - 62	16
HFR3	RFTISRDNAKNTLYLQMNSLKPEDTAVYYCNA	63 - 94	32
CDR-H3	VQQSWTRGGLRSYDY	95 - 109	15
HFR4	WGQGTQVT	110 - 117	8
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGGSLRLSCAASVSTFS	1 - 27	27
	Contact	LQESGGGLVQAGGSLRLSCAASVSTF-	1 - 26	26
	IMGT	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	VSTFSIN---	23 - 29	7
	AbM	VSTFSINAMG	23 - 32	10
	Kabat	-----INAMG	28 - 32	5
	Contact	----SINAMG	27 - 32	6
	IMGT	VSTFSINA--	23 - 30	8
HFR2	Chothia	AMGWYRQAPGKQRELVADI	30 - 48	19
	AbM	---WYRQAPGKQRELVA--	33 - 46	14
	Kabat	---WYRQAPGKQRELVA--	33 - 46	14
	Contact	---WYRQAPGKQRE-----	33 - 43	11
	IMGT	-MGWYRQAPGKQRELVAD-	31 - 47	17
CDR-H2	Chothia	-----SSGGG---------	49 - 53	5
	AbM	---DISSGGGTN-------	47 - 55	9
	Kabat	---DISSGGGTNYADSVKG	47 - 62	16
	Contact	LVADISSGGGTN-------	44 - 55	12
	IMGT	----ISSGGGT--------	48 - 54	7
HFR3	Chothia	TNYADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCNA	54 - 94	41
	AbM	--YADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCNA	56 - 94	39
	Kabat	---------RFTISRDNAKNTLYLQMNSLKPEDTAVYYCNA	63 - 94	32
	Contact	--YADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYC--	56 - 92	37
	IMGT	-NYADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYC--	55 - 92	38
CDR-H3	Chothia	--VQQSWTRGGLRSYDY	95 - 109	15
	AbM	--VQQSWTRGGLRSYDY	95 - 109	15
	Kabat	--VQQSWTRGGLRSYDY	95 - 109	15
	Contact	NAVQQSWTRGGLRSYD-	93 - 108	16
	IMGT	NAVQQSWTRGGLRSYDY	93 - 109	17
HFR4	Chothia	-WGQGTQVT	110 - 117	8
	AbM	-WGQGTQVT	110 - 117	8
	Kabat	-WGQGTQVT	110 - 117	8
	Contact	YWGQGTQVT	109 - 117	9
	IMGT	-WGQGTQVT	110 - 117	8

Accession & Annotations

Accession	CAD22461.1
Source	abYsis-EMBL-IG AJ429748 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C13
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGGSLRLSCAASVSTFSINAMGWYRQAPGKQRELVADISSGGGTNYADSV
KGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCNAVQQSWTRGGLRSYDYWGQGTQVT

DNA Sequence:

ctgcaggagtcagggggaggcttggtgcaggctggggggtctctgagactctcctgtgca
gcctcagtgagcaccttcagtatcaatgccatgggctggtaccgccaggctccagggaag
cagcgcgaattggtcgcagacattagtagtggcggtggcacaaactatgcagactccgtg
aagggccgattcaccatctccagagacaacgccaagaacacactgtatctgcaaatgaac
agcctgaaacctgaggacacggccgtctattactgtaatgcagttcagcagtcatggact
aggggtggtttgcgttcgtatgactactggggccaggggacccaggtcacc

Data Source:

Alignment settings:

Search settings: