abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQPGGSLRLSCQASTSIVS	1 - 27	27
CDR-H1	FNAMA	28 - 32	5
HFR2	WYRQAPGKQRELVA	33 - 46	14
CDR-H2	LITNVGITNYAGSVKG	47 - 62	16
HFR3	RFTISRDTAKNTVYLQMNSLKPEDTAVYYCNA	63 - 94	32
CDR-H3	DSIG	95 - 98	4
HFR4	WGQGTQVT	99 - 106	8
			106

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQPGGSLRLSCQAS-----	1 - 22	22
	AbM	LQESGGGLVQPGGSLRLSCQAS-----	1 - 22	22
	Kabat	LQESGGGLVQPGGSLRLSCQASTSIVS	1 - 27	27
	Contact	LQESGGGLVQPGGSLRLSCQASTSIV-	1 - 26	26
	IMGT	LQESGGGLVQPGGSLRLSCQAS-----	1 - 22	22
CDR-H1	Chothia	TSIVSFN---	23 - 29	7
	AbM	TSIVSFNAMA	23 - 32	10
	Kabat	-----FNAMA	28 - 32	5
	Contact	----SFNAMA	27 - 32	6
	IMGT	TSIVSFNA--	23 - 30	8
HFR2	Chothia	AMAWYRQAPGKQRELVALI	30 - 48	19
	AbM	---WYRQAPGKQRELVA--	33 - 46	14
	Kabat	---WYRQAPGKQRELVA--	33 - 46	14
	Contact	---WYRQAPGKQRE-----	33 - 43	11
	IMGT	-MAWYRQAPGKQRELVAL-	31 - 47	17
CDR-H2	Chothia	-----TNVGI---------	49 - 53	5
	AbM	---LITNVGITN-------	47 - 55	9
	Kabat	---LITNVGITNYAGSVKG	47 - 62	16
	Contact	LVALITNVGITN-------	44 - 55	12
	IMGT	----ITNVGIT--------	48 - 54	7
HFR3	Chothia	TNYAGSVKGRFTISRDTAKNTVYLQMNSLKPEDTAVYYCNA	54 - 94	41
	AbM	--YAGSVKGRFTISRDTAKNTVYLQMNSLKPEDTAVYYCNA	56 - 94	39
	Kabat	---------RFTISRDTAKNTVYLQMNSLKPEDTAVYYCNA	63 - 94	32
	Contact	--YAGSVKGRFTISRDTAKNTVYLQMNSLKPEDTAVYYC--	56 - 92	37
	IMGT	-NYAGSVKGRFTISRDTAKNTVYLQMNSLKPEDTAVYYC--	55 - 92	38
CDR-H3	Chothia	--DSIG	95 - 98	4
	AbM	--DSIG	95 - 98	4
	Kabat	--DSIG	95 - 98	4
	Contact	NADSI-	93 - 97	5
	IMGT	NADSIG	93 - 98	6
HFR4	Chothia	-WGQGTQVT	99 - 106	8
	AbM	-WGQGTQVT	99 - 106	8
	Kabat	-WGQGTQVT	99 - 106	8
	Contact	GWGQGTQVT	98 - 106	9
	IMGT	-WGQGTQVT	99 - 106	8

Accession & Annotations

Accession	CAD22464.1
Source	abYsis-EMBL-IG AJ429751 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C31
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQPGGSLRLSCQASTSIVSFNAMAWYRQAPGKQRELVALITNVGITNYAGSV
KGRFTISRDTAKNTVYLQMNSLKPEDTAVYYCNADSIGWGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggcttggtgcagcctggggggtctctgagactctcctgtcaa
gcctctacaagcatcgtcagtttcaatgccatggcctggtaccgccaggctccagggaag
cagcgcgaattggtcgcacttattactaatgttggtatcacaaactatgcgggctccgtg
aagggccgattcaccatctccagagacactgccaagaacacggtgtatctgcaaatgaac
agcctgaaacctgaggacacggccgtctattactgtaatgcagatagcatcggctggggc
caggggacccaggtcacc

Data Source:

Alignment settings:

Search settings: