abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGLVQPGGSLKLSCAASGSISR	1 - 27	27
CDR-H1	NGMD	28 - 31	4
HFR2	WYRQVPGKEREWVA	32 - 45	14
CDR-H2	TITSRGNTNYADSVKG	46 - 61	16
HFR3	RFTISRDLAKNMVDLQMNSLKPEDTAVYYCRW	62 - 93	32
CDR-H3	RGY	94 - 96	3
HFR4	WGQGTQVT	97 - 104	8
			104

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGLVQPGGSLKLSCAAS-----	1 - 22	22
	AbM	LQQSGGGLVQPGGSLKLSCAAS-----	1 - 22	22
	Kabat	LQQSGGGLVQPGGSLKLSCAASGSISR	1 - 27	27
	Contact	LQQSGGGLVQPGGSLKLSCAASGSIS-	1 - 26	26
	IMGT	LQQSGGGLVQPGGSLKLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GSISRN---	23 - 28	6
	AbM	GSISRNGMD	23 - 31	9
	Kabat	-----NGMD	28 - 31	4
	Contact	----RNGMD	27 - 31	5
	IMGT	GSISRNG--	23 - 29	7
HFR2	Chothia	GMDWYRQVPGKEREWVATI	29 - 47	19
	AbM	---WYRQVPGKEREWVA--	32 - 45	14
	Kabat	---WYRQVPGKEREWVA--	32 - 45	14
	Contact	---WYRQVPGKERE-----	32 - 42	11
	IMGT	-MDWYRQVPGKEREWVAT-	30 - 46	17
CDR-H2	Chothia	-----TSRGN---------	48 - 52	5
	AbM	---TITSRGNTN-------	46 - 54	9
	Kabat	---TITSRGNTNYADSVKG	46 - 61	16
	Contact	WVATITSRGNTN-------	43 - 54	12
	IMGT	----ITSRGNT--------	47 - 53	7
HFR3	Chothia	TNYADSVKGRFTISRDLAKNMVDLQMNSLKPEDTAVYYCRW	53 - 93	41
	AbM	--YADSVKGRFTISRDLAKNMVDLQMNSLKPEDTAVYYCRW	55 - 93	39
	Kabat	---------RFTISRDLAKNMVDLQMNSLKPEDTAVYYCRW	62 - 93	32
	Contact	--YADSVKGRFTISRDLAKNMVDLQMNSLKPEDTAVYYC--	55 - 91	37
	IMGT	-NYADSVKGRFTISRDLAKNMVDLQMNSLKPEDTAVYYC--	54 - 91	38
CDR-H3	Chothia	--RGY	94 - 96	3
	AbM	--RGY	94 - 96	3
	Kabat	--RGY	94 - 96	3
	Contact	RWRG-	92 - 95	4
	IMGT	RWRGY	92 - 96	5
HFR4	Chothia	-WGQGTQVT	97 - 104	8
	AbM	-WGQGTQVT	97 - 104	8
	Kabat	-WGQGTQVT	97 - 104	8
	Contact	YWGQGTQVT	96 - 104	9
	IMGT	-WGQGTQVT	97 - 104	8

Accession & Annotations

Accession	CAD22465.1
Source	abYsis-EMBL-IG AJ429752 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C34
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQQSGGGLVQPGGSLKLSCAASGSISRNGMDWYRQVPGKEREWVATITSRGNTNYADSVK
GRFTISRDLAKNMVDLQMNSLKPEDTAVYYCRWRGYWGQGTQVT

DNA Sequence:

ctgcagcagtctgggggaggcttggtgcagcctggggggtctctgaaactctcctgtgca
gcctctggaagtatcagtcgtaatggtatggactggtaccgccaagttccagggaaggag
cgcgagtgggttgctaccattactagtcgtggcaacacaaattatgcagactccgtgaag
ggccgattcaccatctccagagacctcgccaagaacatggtggatctgcaaatgaacagc
ctgaaacctgaggacacggccgtctattactgccgctggcgcggctattggggccagggg
acccaggtcacc

Data Source:

Alignment settings:

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