abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGLVQAGGSLRLSCVASGSTAK	1 - 27	27
CDR-H1	INAMG	28 - 32	5
HFR2	WYRQAPGKSREFVA	33 - 46	14
CDR-H2	GITSGGFTTFASSVKG	47 - 62	16
HFR3	RFTISRDNAKNTMYLQMNDLKLDDTGVYSCNA	63 - 94	32
CDR-H3	LAPSSY	95 - 100	6
HFR4	WGQGTQVT	101 - 108	8
			108

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGLVQAGGSLRLSCVAS-----	1 - 22	22
	AbM	LQQSGGGLVQAGGSLRLSCVAS-----	1 - 22	22
	Kabat	LQQSGGGLVQAGGSLRLSCVASGSTAK	1 - 27	27
	Contact	LQQSGGGLVQAGGSLRLSCVASGSTA-	1 - 26	26
	IMGT	LQQSGGGLVQAGGSLRLSCVAS-----	1 - 22	22
CDR-H1	Chothia	GSTAKIN---	23 - 29	7
	AbM	GSTAKINAMG	23 - 32	10
	Kabat	-----INAMG	28 - 32	5
	Contact	----KINAMG	27 - 32	6
	IMGT	GSTAKINA--	23 - 30	8
HFR2	Chothia	AMGWYRQAPGKSREFVAGI	30 - 48	19
	AbM	---WYRQAPGKSREFVA--	33 - 46	14
	Kabat	---WYRQAPGKSREFVA--	33 - 46	14
	Contact	---WYRQAPGKSRE-----	33 - 43	11
	IMGT	-MGWYRQAPGKSREFVAG-	31 - 47	17
CDR-H2	Chothia	-----TSGGF---------	49 - 53	5
	AbM	---GITSGGFTT-------	47 - 55	9
	Kabat	---GITSGGFTTFASSVKG	47 - 62	16
	Contact	FVAGITSGGFTT-------	44 - 55	12
	IMGT	----ITSGGFT--------	48 - 54	7
HFR3	Chothia	TTFASSVKGRFTISRDNAKNTMYLQMNDLKLDDTGVYSCNA	54 - 94	41
	AbM	--FASSVKGRFTISRDNAKNTMYLQMNDLKLDDTGVYSCNA	56 - 94	39
	Kabat	---------RFTISRDNAKNTMYLQMNDLKLDDTGVYSCNA	63 - 94	32
	Contact	--FASSVKGRFTISRDNAKNTMYLQMNDLKLDDTGVYSC--	56 - 92	37
	IMGT	-TFASSVKGRFTISRDNAKNTMYLQMNDLKLDDTGVYSC--	55 - 92	38
CDR-H3	Chothia	--LAPSSY	95 - 100	6
	AbM	--LAPSSY	95 - 100	6
	Kabat	--LAPSSY	95 - 100	6
	Contact	NALAPSS-	93 - 99	7
	IMGT	NALAPSSY	93 - 100	8
HFR4	Chothia	-WGQGTQVT	101 - 108	8
	AbM	-WGQGTQVT	101 - 108	8
	Kabat	-WGQGTQVT	101 - 108	8
	Contact	YWGQGTQVT	100 - 108	9
	IMGT	-WGQGTQVT	101 - 108	8

Accession & Annotations

Accession	CAD22466.1
Source	abYsis-EMBL-IG AJ429753 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C35
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQQSGGGLVQAGGSLRLSCVASGSTAKINAMGWYRQAPGKSREFVAGITSGGFTTFASSV
KGRFTISRDNAKNTMYLQMNDLKLDDTGVYSCNALAPSSYWGQGTQVT

DNA Sequence:

ctgcagcagtcagggggaggcttggtgcaggctggggggtctctgagactctcctgtgta
gcctctggaagcaccgcgaagatcaatgccatgggctggtaccgccaggctccagggaag
tcgcgcgaattcgtcgcaggtattactagtggtggctttacaacatttgcaagctccgtg
aagggccgattcaccatctccagagacaacgccaagaacacaatgtatctacaaatgaac
gacctgaaacttgacgacacgggcgtctactcttgcaatgccctggcaccctctagttac
tggggccaggggacccaggtcacc

Data Source:

Alignment settings:

Search settings: