abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGGSLRLSCAPSTRTFG	1 - 27	27
CDR-H1	IYQTA	28 - 32	5
HFR2	WFRQVPGKEREFVA	33 - 46	14
CDR-H2	TISGYGTSTYYADSVKG	47 - 63	17
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	64 - 95	32
CDR-H3	DQTSLQLTKVSAYRY	96 - 110	15
HFR4	WGQGTQVT	111 - 118	8
			118

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGGSLRLSCAPS-----	1 - 22	22
	AbM	LQESGGGLVQAGGSLRLSCAPS-----	1 - 22	22
	Kabat	LQESGGGLVQAGGSLRLSCAPSTRTFG	1 - 27	27
	Contact	LQESGGGLVQAGGSLRLSCAPSTRTF-	1 - 26	26
	IMGT	LQESGGGLVQAGGSLRLSCAPS-----	1 - 22	22
CDR-H1	Chothia	TRTFGIY---	23 - 29	7
	AbM	TRTFGIYQTA	23 - 32	10
	Kabat	-----IYQTA	28 - 32	5
	Contact	----GIYQTA	27 - 32	6
	IMGT	TRTFGIYQ--	23 - 30	8
HFR2	Chothia	QTAWFRQVPGKEREFVATI	30 - 48	19
	AbM	---WFRQVPGKEREFVA--	33 - 46	14
	Kabat	---WFRQVPGKEREFVA--	33 - 46	14
	Contact	---WFRQVPGKERE-----	33 - 43	11
	IMGT	-TAWFRQVPGKEREFVAT-	31 - 47	17
CDR-H2	Chothia	-----SGYGTS---------	49 - 54	6
	AbM	---TISGYGTSTY-------	47 - 56	10
	Kabat	---TISGYGTSTYYADSVKG	47 - 63	17
	Contact	FVATISGYGTSTY-------	44 - 56	13
	IMGT	----ISGYGTST--------	48 - 55	8
HFR3	Chothia	TYYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	55 - 95	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	64 - 95	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	57 - 93	37
	IMGT	-YYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--DQTSLQLTKVSAYRY	96 - 110	15
	AbM	--DQTSLQLTKVSAYRY	96 - 110	15
	Kabat	--DQTSLQLTKVSAYRY	96 - 110	15
	Contact	AADQTSLQLTKVSAYR-	94 - 109	16
	IMGT	AADQTSLQLTKVSAYRY	94 - 110	17
HFR4	Chothia	-WGQGTQVT	111 - 118	8
	AbM	-WGQGTQVT	111 - 118	8
	Kabat	-WGQGTQVT	111 - 118	8
	Contact	YWGQGTQVT	110 - 118	9
	IMGT	-WGQGTQVT	111 - 118	8

Accession & Annotations

Accession	CAD22468.1
Source	abYsis-EMBL-IG AJ429755 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C96
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGGSLRLSCAPSTRTFGIYQTAWFRQVPGKEREFVATISGYGTSTYYADS
VKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAADQTSLQLTKVSAYRYWGQGTQVT

DNA Sequence:

ctgcaggagtctggaggaggattggtgcaggctgggggctctctgagactctcctgtgca
ccctctacacgcaccttcggtatttatcagacggcctggttccgccaggttccagggaag
gagcgtgaatttgtagcaactattagcgggtatggtactagcacatattatgcagactcc
gtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatg
aacagcctgaaacctgaggacacggccgtttattactgtgcagccgatcagacttcactg
caacttaccaaggtttccgcttaccgctactggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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