abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGLVQAGGSLRLSCAASGGTFT	1 - 27	27
CDR-H1	MYAID	28 - 32	5
HFR2	WLRQAPGKEREFVG	33 - 46	14
CDR-H2	SISAGGGSTFYAESVKG	47 - 63	17
HFR3	RFTISRDNSKNTVSLQMNNLKPEDTAVYYCAA	64 - 95	32
CDR-H3	RRGIATMAPTSYAT	96 - 109	14
HFR4	WGQGTQVT	110 - 117	8
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQQSGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQQSGGGLVQAGGSLRLSCAASGGTFT	1 - 27	27
	Contact	LQQSGGGLVQAGGSLRLSCAASGGTF-	1 - 26	26
	IMGT	LQQSGGGLVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GGTFTMY---	23 - 29	7
	AbM	GGTFTMYAID	23 - 32	10
	Kabat	-----MYAID	28 - 32	5
	Contact	----TMYAID	27 - 32	6
	IMGT	GGTFTMYA--	23 - 30	8
HFR2	Chothia	AIDWLRQAPGKEREFVGSI	30 - 48	19
	AbM	---WLRQAPGKEREFVG--	33 - 46	14
	Kabat	---WLRQAPGKEREFVG--	33 - 46	14
	Contact	---WLRQAPGKERE-----	33 - 43	11
	IMGT	-IDWLRQAPGKEREFVGS-	31 - 47	17
CDR-H2	Chothia	-----SAGGGS---------	49 - 54	6
	AbM	---SISAGGGSTF-------	47 - 56	10
	Kabat	---SISAGGGSTFYAESVKG	47 - 63	17
	Contact	FVGSISAGGGSTF-------	44 - 56	13
	IMGT	----ISAGGGST--------	48 - 55	8
HFR3	Chothia	TFYAESVKGRFTISRDNSKNTVSLQMNNLKPEDTAVYYCAA	55 - 95	41
	AbM	--YAESVKGRFTISRDNSKNTVSLQMNNLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISRDNSKNTVSLQMNNLKPEDTAVYYCAA	64 - 95	32
	Contact	--YAESVKGRFTISRDNSKNTVSLQMNNLKPEDTAVYYC--	57 - 93	37
	IMGT	-FYAESVKGRFTISRDNSKNTVSLQMNNLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--RRGIATMAPTSYAT	96 - 109	14
	AbM	--RRGIATMAPTSYAT	96 - 109	14
	Kabat	--RRGIATMAPTSYAT	96 - 109	14
	Contact	AARRGIATMAPTSYA-	94 - 108	15
	IMGT	AARRGIATMAPTSYAT	94 - 109	16
HFR4	Chothia	-WGQGTQVT	110 - 117	8
	AbM	-WGQGTQVT	110 - 117	8
	Kabat	-WGQGTQVT	110 - 117	8
	Contact	TWGQGTQVT	109 - 117	9
	IMGT	-WGQGTQVT	110 - 117	8

Accession & Annotations

Accession	CAD22470.1
Source	abYsis-EMBL-IG AJ429757 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C110
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQQSGGGLVQAGGSLRLSCAASGGTFTMYAIDWLRQAPGKEREFVGSISAGGGSTFYAES
VKGRFTISRDNSKNTVSLQMNNLKPEDTAVYYCAARRGIATMAPTSYATWGQGTQVT

DNA Sequence:

ctgcagcagtctgggggaggattggtgcaggctgggggctctctgaggctctcctgtgca
gcctctggaggcaccttcactatgtatgccatcgactggctccgccaggctccagggaag
gagcgtgagtttgtagggagtatcagcgcgggtggtggtagtacattttatgcagagtcc
gtgaagggccgattcaccatctccagagacaactccaagaacacggtgtcactgcaaatg
aacaacttgaaacctgaggatacggccgtctattactgtgcagcgcgtcggggtatagcg
actatggcccccacctcctatgccacctggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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