abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQTGGSLRLSCAASGRTFS	1 - 27	27
CDR-H1	NYHMG	28 - 32	5
HFR2	WFRQAAGKEREFVA	33 - 46	14
CDR-H2	HMTGTGSITHYADSVKG	47 - 63	17
HFR3	RFTISGDSAKNTVYLQMNNLKPEDTAVYYCAA	64 - 95	32
CDR-H3	TVLARRPAPEAYDY	96 - 109	14
HFR4	WGQGTQVT	110 - 117	8
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQTGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQTGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQTGGSLRLSCAASGRTFS	1 - 27	27
	Contact	LQESGGGLVQTGGSLRLSCAASGRTF-	1 - 26	26
	IMGT	LQESGGGLVQTGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GRTFSNY---	23 - 29	7
	AbM	GRTFSNYHMG	23 - 32	10
	Kabat	-----NYHMG	28 - 32	5
	Contact	----SNYHMG	27 - 32	6
	IMGT	GRTFSNYH--	23 - 30	8
HFR2	Chothia	HMGWFRQAAGKEREFVAHM	30 - 48	19
	AbM	---WFRQAAGKEREFVA--	33 - 46	14
	Kabat	---WFRQAAGKEREFVA--	33 - 46	14
	Contact	---WFRQAAGKERE-----	33 - 43	11
	IMGT	-MGWFRQAAGKEREFVAH-	31 - 47	17
CDR-H2	Chothia	-----TGTGSI---------	49 - 54	6
	AbM	---HMTGTGSITH-------	47 - 56	10
	Kabat	---HMTGTGSITHYADSVKG	47 - 63	17
	Contact	FVAHMTGTGSITH-------	44 - 56	13
	IMGT	----MTGTGSIT--------	48 - 55	8
HFR3	Chothia	THYADSVKGRFTISGDSAKNTVYLQMNNLKPEDTAVYYCAA	55 - 95	41
	AbM	--YADSVKGRFTISGDSAKNTVYLQMNNLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISGDSAKNTVYLQMNNLKPEDTAVYYCAA	64 - 95	32
	Contact	--YADSVKGRFTISGDSAKNTVYLQMNNLKPEDTAVYYC--	57 - 93	37
	IMGT	-HYADSVKGRFTISGDSAKNTVYLQMNNLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--TVLARRPAPEAYDY	96 - 109	14
	AbM	--TVLARRPAPEAYDY	96 - 109	14
	Kabat	--TVLARRPAPEAYDY	96 - 109	14
	Contact	AATVLARRPAPEAYD-	94 - 108	15
	IMGT	AATVLARRPAPEAYDY	94 - 109	16
HFR4	Chothia	-WGQGTQVT	110 - 117	8
	AbM	-WGQGTQVT	110 - 117	8
	Kabat	-WGQGTQVT	110 - 117	8
	Contact	YWGQGTQVT	109 - 117	9
	IMGT	-WGQGTQVT	110 - 117	8

Accession & Annotations

Accession	CAD22473.1
Source	abYsis-EMBL-IG AJ429760 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C204
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQTGGSLRLSCAASGRTFSNYHMGWFRQAAGKEREFVAHMTGTGSITHYADS
VKGRFTISGDSAKNTVYLQMNNLKPEDTAVYYCAATVLARRPAPEAYDYWGQGTQVT

DNA Sequence:

ctgcaggagtcagggggaggattggtgcagactggggggtctctgaggctctcctgtgca
gcctctggacgcaccttcagtaactatcacatgggctggttccgccaggcggcagggaaa
gagcgtgaatttgtagcacatatgaccgggactggtagtatcacacactatgcagactcc
gtgaagggacgattcaccatctccggagacagcgccaagaacacggtgtatctgcaaatg
aacaacctgaaacctgaagacacggccgtttactactgcgcagcaaccgtcctcgctcgg
cggccggcaccagaggcatatgactactggggtcaggggacccaggtcacc

Data Source:

Alignment settings:

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