abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGGSLRLSCAASGSTFS	1 - 27	27
CDR-H1	INAIR	28 - 32	5
HFR2	WYRQAPGKQRELVA	33 - 46	14
CDR-H2	AISIGGTTNYADSVKG	47 - 62	16
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	63 - 94	32
CDR-H3	PGPYSDYETMGYEYDY	95 - 110	16
HFR4	WGQGTQVT	111 - 118	8
			118

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGGSLRLSCAASGSTFS	1 - 27	27
	Contact	LQESGGGLVQAGGSLRLSCAASGSTF-	1 - 26	26
	IMGT	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GSTFSIN---	23 - 29	7
	AbM	GSTFSINAIR	23 - 32	10
	Kabat	-----INAIR	28 - 32	5
	Contact	----SINAIR	27 - 32	6
	IMGT	GSTFSINA--	23 - 30	8
HFR2	Chothia	AIRWYRQAPGKQRELVAAI	30 - 48	19
	AbM	---WYRQAPGKQRELVA--	33 - 46	14
	Kabat	---WYRQAPGKQRELVA--	33 - 46	14
	Contact	---WYRQAPGKQRE-----	33 - 43	11
	IMGT	-IRWYRQAPGKQRELVAA-	31 - 47	17
CDR-H2	Chothia	-----SIGGT---------	49 - 53	5
	AbM	---AISIGGTTN-------	47 - 55	9
	Kabat	---AISIGGTTNYADSVKG	47 - 62	16
	Contact	LVAAISIGGTTN-------	44 - 55	12
	IMGT	----ISIGGTT--------	48 - 54	7
HFR3	Chothia	TNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	54 - 94	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	56 - 94	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	63 - 94	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	56 - 92	37
	IMGT	-NYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	55 - 92	38
CDR-H3	Chothia	--PGPYSDYETMGYEYDY	95 - 110	16
	AbM	--PGPYSDYETMGYEYDY	95 - 110	16
	Kabat	--PGPYSDYETMGYEYDY	95 - 110	16
	Contact	NAPGPYSDYETMGYEYD-	93 - 109	17
	IMGT	NAPGPYSDYETMGYEYDY	93 - 110	18
HFR4	Chothia	-WGQGTQVT	111 - 118	8
	AbM	-WGQGTQVT	111 - 118	8
	Kabat	-WGQGTQVT	111 - 118	8
	Contact	YWGQGTQVT	110 - 118	9
	IMGT	-WGQGTQVT	111 - 118	8

Accession & Annotations

Accession	CAD22476.1
Source	abYsis-EMBL-IG AJ429763 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C214
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGGSLRLSCAASGSTFSINAIRWYRQAPGKQRELVAAISIGGTTNYADSV
KGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCNAPGPYSDYETMGYEYDYWGQGTQVT

DNA Sequence:

ctgcaggagtcagggggaggcttggtgcaggctggggggtctctgagactctcctgtgca
gcctctggaagcaccttcagtatcaatgccatacgctggtaccgccaggctccagggaag
cagcgcgagttggtcgcagctattagtattggtggtaccacaaactatgctgactccgtg
aagggccgattcaccatctccagagacaacgccaagaacacagtgtatctgcaaatgaac
agcctgaaacctgaggacacggccgtgtattactgtaatgcccctgggccatatagcgac
tatgaaactatgggttatgagtatgactactggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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