abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGSVQAGGSLRLSCAASGRAFS	1 - 27	27
CDR-H1	AYTMG	28 - 32	5
HFR2	WFRQPPGKEREFVA	33 - 46	14
CDR-H2	HIGRDDGMTHYADSVKG	47 - 63	17
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	64 - 95	32
CDR-H3	TILARRPSPGAYDY	96 - 109	14
HFR4	WGQGTQVT	110 - 117	8
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGSVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQQSGGGSVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQQSGGGSVQAGGSLRLSCAASGRAFS	1 - 27	27
	Contact	LQQSGGGSVQAGGSLRLSCAASGRAF-	1 - 26	26
	IMGT	LQQSGGGSVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GRAFSAY---	23 - 29	7
	AbM	GRAFSAYTMG	23 - 32	10
	Kabat	-----AYTMG	28 - 32	5
	Contact	----SAYTMG	27 - 32	6
	IMGT	GRAFSAYT--	23 - 30	8
HFR2	Chothia	TMGWFRQPPGKEREFVAHI	30 - 48	19
	AbM	---WFRQPPGKEREFVA--	33 - 46	14
	Kabat	---WFRQPPGKEREFVA--	33 - 46	14
	Contact	---WFRQPPGKERE-----	33 - 43	11
	IMGT	-MGWFRQPPGKEREFVAH-	31 - 47	17
CDR-H2	Chothia	-----GRDDGM---------	49 - 54	6
	AbM	---HIGRDDGMTH-------	47 - 56	10
	Kabat	---HIGRDDGMTHYADSVKG	47 - 63	17
	Contact	FVAHIGRDDGMTH-------	44 - 56	13
	IMGT	----IGRDDGMT--------	48 - 55	8
HFR3	Chothia	THYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	55 - 95	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	64 - 95	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	57 - 93	37
	IMGT	-HYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--TILARRPSPGAYDY	96 - 109	14
	AbM	--TILARRPSPGAYDY	96 - 109	14
	Kabat	--TILARRPSPGAYDY	96 - 109	14
	Contact	AATILARRPSPGAYD-	94 - 108	15
	IMGT	AATILARRPSPGAYDY	94 - 109	16
HFR4	Chothia	-WGQGTQVT	110 - 117	8
	AbM	-WGQGTQVT	110 - 117	8
	Kabat	-WGQGTQVT	110 - 117	8
	Contact	YWGQGTQVT	109 - 117	9
	IMGT	-WGQGTQVT	110 - 117	8

Accession & Annotations

Accession	CAD22478.1
Source	abYsis-EMBL-IG AJ429765 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C225
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQQSGGGSVQAGGSLRLSCAASGRAFSAYTMGWFRQPPGKEREFVAHIGRDDGMTHYADS
VKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAATILARRPSPGAYDYWGQGTQVT

DNA Sequence:

ctgcagcagtctgggggaggatcggtgcaggctgggggctctctgagactctcctgtgca
gcctctggacgcgccttcagtgcgtatacaatgggctggttccgccaacctccagggaag
gagcgtgaatttgttgcgcatattggccgggatgatggtatgacacactatgcagactcc
gtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatg
aacagcctgaaaccggaagacacggccgtttattactgtgcagcaaccattctcgctcgg
cggccgtcaccaggggcatatgactactggggccaggggacgcaggtcacc

Data Source:

Alignment settings:

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