abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGLVQAGGSLRLSCAASGRAFS	1 - 27	27
CDR-H1	SYHMG	28 - 32	5
HFR2	WFRQAAGKEREFVA	33 - 46	14
CDR-H2	HMTGTGGSTHYADSVKG	47 - 63	17
HFR3	RFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	64 - 95	32
CDR-H3	TILAQRPTPGAYEY	96 - 109	14
HFR4	WGPGTQVT	110 - 117	8
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQQSGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQQSGGGLVQAGGSLRLSCAASGRAFS	1 - 27	27
	Contact	LQQSGGGLVQAGGSLRLSCAASGRAF-	1 - 26	26
	IMGT	LQQSGGGLVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GRAFSSY---	23 - 29	7
	AbM	GRAFSSYHMG	23 - 32	10
	Kabat	-----SYHMG	28 - 32	5
	Contact	----SSYHMG	27 - 32	6
	IMGT	GRAFSSYH--	23 - 30	8
HFR2	Chothia	HMGWFRQAAGKEREFVAHM	30 - 48	19
	AbM	---WFRQAAGKEREFVA--	33 - 46	14
	Kabat	---WFRQAAGKEREFVA--	33 - 46	14
	Contact	---WFRQAAGKERE-----	33 - 43	11
	IMGT	-MGWFRQAAGKEREFVAH-	31 - 47	17
CDR-H2	Chothia	-----TGTGGS---------	49 - 54	6
	AbM	---HMTGTGGSTH-------	47 - 56	10
	Kabat	---HMTGTGGSTHYADSVKG	47 - 63	17
	Contact	FVAHMTGTGGSTH-------	44 - 56	13
	IMGT	----MTGTGGST--------	48 - 55	8
HFR3	Chothia	THYADSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	55 - 95	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	64 - 95	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYC--	57 - 93	37
	IMGT	-HYADSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--TILAQRPTPGAYEY	96 - 109	14
	AbM	--TILAQRPTPGAYEY	96 - 109	14
	Kabat	--TILAQRPTPGAYEY	96 - 109	14
	Contact	AATILAQRPTPGAYE-	94 - 108	15
	IMGT	AATILAQRPTPGAYEY	94 - 109	16
HFR4	Chothia	-WGPGTQVT	110 - 117	8
	AbM	-WGPGTQVT	110 - 117	8
	Kabat	-WGPGTQVT	110 - 117	8
	Contact	YWGPGTQVT	109 - 117	9
	IMGT	-WGPGTQVT	110 - 117	8

Accession & Annotations

Accession	CAD22480.1
Source	abYsis-EMBL-IG AJ429767 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C228
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQQSGGGLVQAGGSLRLSCAASGRAFSSYHMGWFRQAAGKEREFVAHMTGTGGSTHYADS
VKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYCAATILAQRPTPGAYEYWGPGTQVT

DNA Sequence:

ctgcagcagtctgggggaggattggtgcaggctgggggctctctgaggctctcctgtgca
gcctctggccgcgccttcagtagttatcacatgggctggttccgccaggcggcagggaag
gagcgtgagtttgtagcacatatgaccgggactggcggtagcacacactatgcagactcc
gtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatg
aacaacctgaaacccgaagacacggccgtttattactgcgcagcaaccatcctcgctcag
cggccgacaccaggggcatatgagtattggggtccggggacccaggtcacc

Data Source:

Alignment settings:

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