abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGDSLRLSCVASGLTFS	1 - 27	27
CDR-H1	SYTMG	28 - 32	5
HFR2	WFRQAPGKEREFVV	33 - 46	14
CDR-H2	HITGSGGLTYYVDSVKG	47 - 63	17
HFR3	RFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	64 - 95	32
CDR-H3	TILARRPSPGAYDY	96 - 109	14
HFR4	WGQGTQVT	110 - 117	8
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGDSLRLSCVAS-----	1 - 22	22
	AbM	LQESGGGLVQAGDSLRLSCVAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGDSLRLSCVASGLTFS	1 - 27	27
	Contact	LQESGGGLVQAGDSLRLSCVASGLTF-	1 - 26	26
	IMGT	LQESGGGLVQAGDSLRLSCVAS-----	1 - 22	22
CDR-H1	Chothia	GLTFSSY---	23 - 29	7
	AbM	GLTFSSYTMG	23 - 32	10
	Kabat	-----SYTMG	28 - 32	5
	Contact	----SSYTMG	27 - 32	6
	IMGT	GLTFSSYT--	23 - 30	8
HFR2	Chothia	TMGWFRQAPGKEREFVVHI	30 - 48	19
	AbM	---WFRQAPGKEREFVV--	33 - 46	14
	Kabat	---WFRQAPGKEREFVV--	33 - 46	14
	Contact	---WFRQAPGKERE-----	33 - 43	11
	IMGT	-MGWFRQAPGKEREFVVH-	31 - 47	17
CDR-H2	Chothia	-----TGSGGL---------	49 - 54	6
	AbM	---HITGSGGLTY-------	47 - 56	10
	Kabat	---HITGSGGLTYYVDSVKG	47 - 63	17
	Contact	FVVHITGSGGLTY-------	44 - 56	13
	IMGT	----ITGSGGLT--------	48 - 55	8
HFR3	Chothia	TYYVDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	55 - 95	41
	AbM	--YVDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISRDNAKNTVYLQMNNLKPEDTAVYYCAA	64 - 95	32
	Contact	--YVDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYC--	57 - 93	37
	IMGT	-YYVDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--TILARRPSPGAYDY	96 - 109	14
	AbM	--TILARRPSPGAYDY	96 - 109	14
	Kabat	--TILARRPSPGAYDY	96 - 109	14
	Contact	AATILARRPSPGAYD-	94 - 108	15
	IMGT	AATILARRPSPGAYDY	94 - 109	16
HFR4	Chothia	-WGQGTQVT	110 - 117	8
	AbM	-WGQGTQVT	110 - 117	8
	Kabat	-WGQGTQVT	110 - 117	8
	Contact	YWGQGTQVT	109 - 117	9
	IMGT	-WGQGTQVT	110 - 117	8

Accession & Annotations

Accession	CAD22481.1
Source	abYsis-EMBL-IG AJ429768 Submitted 02-FEB-2002 Updated 02-FEB-2002
Name	immunoglobulin heavy chain variable region
Clone	C229
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (30-JAN-2002) to the INSDC. Harmsen M.M., Notifiable Diseases and Pathology, Institute for Animal Science and Health, Edelhertweg 15, 8200 AB Lelystad, NETHERLANDS. Harmsen M.M., Smits C.B. 'Stimulation of chymosin secretion by yeast cells by simultaneous expression of chymosin-binding llama single-domain antibody fragments' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGDSLRLSCVASGLTFSSYTMGWFRQAPGKEREFVVHITGSGGLTYYVDS
VKGRFTISRDNAKNTVYLQMNNLKPEDTAVYYCAATILARRPSPGAYDYWGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggattggtgcaggctggggactctctgagactctcctgtgta
gcttctggactcaccttcagtagctataccatgggctggttccgccaggctccagggaag
gagcgtgagtttgtagtgcatattacaggaagtggaggactcacatattatgtagactcc
gtgaagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatg
aacaacctgaaacctgaagacacggccgtttattactgtgcagcaaccatcctcgctcgg
cggccgtcaccaggggcatatgactactggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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