abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQAGGSLRLTCALSERTST	1 - 30	30
CDR-H1	SYAQG	31 - 35	5
HFR2	WFRQPPGKEREFVA	36 - 49	14
CDR-H2	SLRTHDGNTHYTDSVKG	50 - 66	17
HFR3	RFTISRDNAENTLYLQMNSLKTEDTAVYYCAA	67 - 98	32
CDR-H3	SLGYSGAYASGYDY	99 - 112	14
HFR4	WGQGTQVTVSS	113 - 123	11
Tail	GGLPETGGHHHHHH	123 - 137	14
			137

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQAGGSLRLTCALS-----	1 - 25	25
	AbM	QVQLQESGGGLVQAGGSLRLTCALS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQAGGSLRLTCALSERTST	1 - 30	30
	Contact	QVQLQESGGGLVQAGGSLRLTCALSERTS-	1 - 29	29
	IMGT	QVQLQESGGGLVQAGGSLRLTCALS-----	1 - 25	25
CDR-H1	Chothia	ERTSTSY---	26 - 32	7
	AbM	ERTSTSYAQG	26 - 35	10
	Kabat	-----SYAQG	31 - 35	5
	Contact	----TSYAQG	30 - 35	6
	IMGT	ERTSTSYA--	26 - 33	8
HFR2	Chothia	AQGWFRQPPGKEREFVASL	33 - 51	19
	AbM	---WFRQPPGKEREFVA--	36 - 49	14
	Kabat	---WFRQPPGKEREFVA--	36 - 49	14
	Contact	---WFRQPPGKERE-----	36 - 46	11
	IMGT	-QGWFRQPPGKEREFVAS-	34 - 50	17
CDR-H2	Chothia	-----RTHDGN---------	52 - 57	6
	AbM	---SLRTHDGNTH-------	50 - 59	10
	Kabat	---SLRTHDGNTHYTDSVKG	50 - 66	17
	Contact	FVASLRTHDGNTH-------	47 - 59	13
	IMGT	----LRTHDGNT--------	51 - 58	8
HFR3	Chothia	THYTDSVKGRFTISRDNAENTLYLQMNSLKTEDTAVYYCAA	58 - 98	41
	AbM	--YTDSVKGRFTISRDNAENTLYLQMNSLKTEDTAVYYCAA	60 - 98	39
	Kabat	---------RFTISRDNAENTLYLQMNSLKTEDTAVYYCAA	67 - 98	32
	Contact	--YTDSVKGRFTISRDNAENTLYLQMNSLKTEDTAVYYC--	60 - 96	37
	IMGT	-HYTDSVKGRFTISRDNAENTLYLQMNSLKTEDTAVYYC--	59 - 96	38
CDR-H3	Chothia	--SLGYSGAYASGYDY	99 - 112	14
	AbM	--SLGYSGAYASGYDY	99 - 112	14
	Kabat	--SLGYSGAYASGYDY	99 - 112	14
	Contact	AASLGYSGAYASGYD-	97 - 111	15
	IMGT	AASLGYSGAYASGYDY	97 - 112	16
HFR4	Chothia	-WGQGTQVTVSS	113 - 123	11
	AbM	-WGQGTQVTVSS	113 - 123	11
	Kabat	-WGQGTQVTVSS	113 - 123	11
	Contact	YWGQGTQVTVSS	112 - 123	12
	IMGT	-WGQGTQVTVSS	113 - 123	11

Accession & Annotations

Accession	5tjw_K
Source	PDB 5tjw Submitted 05-OCT-2016 Updated 01-NOV-2017
Name	INFLUENZA A VIRUS NUCLEOPROTEIN IN COMPLEX WITH INHIBITORY NANOBODY
Organism	Vicugna pacos
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	HANKE L., KNOCKENHAUER E., BREWER C., VAN DIEST E., SCHMIDT I., SCHWARTZ U., PLOEGH L. 'THE ANTIVIRAL MECHANISM OF AN INFLUENZA A VIRUS NUCLEOPROTEIN-SPECIFIC SINGLE-DOMAIN ANTIBODY FRAGMENT.' MBIO V. 7 2016 ESSN 2150-7511

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQAGGSLRLTCALSERTSTSYAQGWFRQPPGKEREFVASLRTHDGNTHY
TDSVKGRFTISRDNAENTLYLQMNSLKTEDTAVYYCAASLGYSGAYASGYDYWGQGTQVT
VSSGGLPETGGHHHHHH