abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVPPGGSLRLSCAASERTFS	1 - 27	27
CDR-H1	DYSMA	28 - 32	5
HFR2	WFRQAPGKDSEFVG	33 - 46	14
CDR-H2	VISWGGGPYYGDSVKG	47 - 62	16
HFR3	RFTISRDNAKNRMYLQMNSLKPEDTATYYCAA	63 - 94	32
CDR-H3	TLDWGTIARMSRAGMYDY	95 - 112	18
HFR4	WGQGTQVT	113 - 120	8
			120

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVPPGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVPPGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVPPGGSLRLSCAASERTFS	1 - 27	27
	Contact	LQESGGGLVPPGGSLRLSCAASERTF-	1 - 26	26
	IMGT	LQESGGGLVPPGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	ERTFSDY---	23 - 29	7
	AbM	ERTFSDYSMA	23 - 32	10
	Kabat	-----DYSMA	28 - 32	5
	Contact	----SDYSMA	27 - 32	6
	IMGT	ERTFSDYS--	23 - 30	8
HFR2	Chothia	SMAWFRQAPGKDSEFVGVI	30 - 48	19
	AbM	---WFRQAPGKDSEFVG--	33 - 46	14
	Kabat	---WFRQAPGKDSEFVG--	33 - 46	14
	Contact	---WFRQAPGKDSE-----	33 - 43	11
	IMGT	-MAWFRQAPGKDSEFVGV-	31 - 47	17
CDR-H2	Chothia	-----SWGGG---------	49 - 53	5
	AbM	---VISWGGGPY-------	47 - 55	9
	Kabat	---VISWGGGPYYGDSVKG	47 - 62	16
	Contact	FVGVISWGGGPY-------	44 - 55	12
	IMGT	----ISWGGGP--------	48 - 54	7
HFR3	Chothia	PYYGDSVKGRFTISRDNAKNRMYLQMNSLKPEDTATYYCAA	54 - 94	41
	AbM	--YGDSVKGRFTISRDNAKNRMYLQMNSLKPEDTATYYCAA	56 - 94	39
	Kabat	---------RFTISRDNAKNRMYLQMNSLKPEDTATYYCAA	63 - 94	32
	Contact	--YGDSVKGRFTISRDNAKNRMYLQMNSLKPEDTATYYC--	56 - 92	37
	IMGT	-YYGDSVKGRFTISRDNAKNRMYLQMNSLKPEDTATYYC--	55 - 92	38
CDR-H3	Chothia	--TLDWGTIARMSRAGMYDY	95 - 112	18
	AbM	--TLDWGTIARMSRAGMYDY	95 - 112	18
	Kabat	--TLDWGTIARMSRAGMYDY	95 - 112	18
	Contact	AATLDWGTIARMSRAGMYD-	93 - 111	19
	IMGT	AATLDWGTIARMSRAGMYDY	93 - 112	20
HFR4	Chothia	-WGQGTQVT	113 - 120	8
	AbM	-WGQGTQVT	113 - 120	8
	Kabat	-WGQGTQVT	113 - 120	8
	Contact	YWGQGTQVT	112 - 120	9
	IMGT	-WGQGTQVT	113 - 120	8

Accession & Annotations

Accession	CAH18846.1
Source	abYsis-EMBL-IG AJ811550 Submitted 20-AUG-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	M168
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (19-AUG-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., Van Solt C.B., Van Keulen L. 'Selection of llama single-domain antibody fragments binding to recombinant bovine prion protein in ELISA' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVPPGGSLRLSCAASERTFSDYSMAWFRQAPGKDSEFVGVISWGGGPYYGDSV
KGRFTISRDNAKNRMYLQMNSLKPEDTATYYCAATLDWGTIARMSRAGMYDYWGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggattggtgccgcctgggggctctctgagactgtcctgtgca
gcctccgaacgcaccttcagtgattattccatggcctggttccgccaggctccagggaag
gacagtgagtttgtaggagttattagctggggtggtggtccatactatggcgactccgtg
aagggccgattcaccatctccagagacaacgccaagaacaggatgtacctgcaaatgaac
agcctgaaacctgaggacacggccacttattactgtgcagcgactctggactgggggact
atagcgcgtatgtctagagcgggaatgtatgactactggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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