abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQPGGSLRLSCAASGFTFS	1 - 27	27
CDR-H1	DYVMS	28 - 32	5
HFR2	WVRQAPGKGLEWVS	33 - 46	14
CDR-H2	AINFVGSSTSYADSVKG	47 - 63	17
HFR3	RFTISRDNAKNTLYLQMNSLKPEDTAVYYCTK	64 - 95	32
CDR-H3	LGSDP	96 - 100	5
HFR4	TGQGTQVT	101 - 108	8
			108

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQPGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQPGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQPGGSLRLSCAASGFTFS	1 - 27	27
	Contact	LQESGGGLVQPGGSLRLSCAASGFTF-	1 - 26	26
	IMGT	LQESGGGLVQPGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GFTFSDY---	23 - 29	7
	AbM	GFTFSDYVMS	23 - 32	10
	Kabat	-----DYVMS	28 - 32	5
	Contact	----SDYVMS	27 - 32	6
	IMGT	GFTFSDYV--	23 - 30	8
HFR2	Chothia	VMSWVRQAPGKGLEWVSAI	30 - 48	19
	AbM	---WVRQAPGKGLEWVS--	33 - 46	14
	Kabat	---WVRQAPGKGLEWVS--	33 - 46	14
	Contact	---WVRQAPGKGLE-----	33 - 43	11
	IMGT	-MSWVRQAPGKGLEWVSA-	31 - 47	17
CDR-H2	Chothia	-----NFVGSS---------	49 - 54	6
	AbM	---AINFVGSSTS-------	47 - 56	10
	Kabat	---AINFVGSSTSYADSVKG	47 - 63	17
	Contact	WVSAINFVGSSTS-------	44 - 56	13
	IMGT	----INFVGSST--------	48 - 55	8
HFR3	Chothia	TSYADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCTK	55 - 95	41
	AbM	--YADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCTK	57 - 95	39
	Kabat	---------RFTISRDNAKNTLYLQMNSLKPEDTAVYYCTK	64 - 95	32
	Contact	--YADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYC--	57 - 93	37
	IMGT	-SYADSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--LGSDP	96 - 100	5
	AbM	--LGSDP	96 - 100	5
	Kabat	--LGSDP	96 - 100	5
	Contact	TKLGSD-	94 - 99	6
	IMGT	TKLGSDP	94 - 100	7
HFR4	Chothia	-TGQGTQVT	101 - 108	8
	AbM	-TGQGTQVT	101 - 108	8
	Kabat	-TGQGTQVT	101 - 108	8
	Contact	PTGQGTQVT	100 - 108	9
	IMGT	-TGQGTQVT	101 - 108	8

Accession & Annotations

Accession	CAH18848.1
Source	abYsis-EMBL-IG AJ811552 Submitted 20-AUG-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	M171
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (19-AUG-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., Van Solt C.B., Van Keulen L. 'Selection of llama single-domain antibody fragments binding to recombinant bovine prion protein in ELISA' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQPGGSLRLSCAASGFTFSDYVMSWVRQAPGKGLEWVSAINFVGSSTSYADS
VKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCTKLGSDPTGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggcttggtgcagcctggggggtctctgagactctcctgtgca
gcctctggattcaccttcagcgactatgtcatgagctgggtccgccaggctccaggaaag
gggctcgagtgggtctcagctattaattttgttggtagtagcacaagctatgcagactcc
gtgaagggccgattcaccatctccagagacaacgccaagaacacgctgtatctgcaaatg
aacagcctgaaacctgaggacacggccgtgtattactgtacaaaactcgggagcgacccc
acgggccaggggacccaggtcacc

Data Source:

Alignment settings:

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