abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGGSLRLSCVASGITFS	1 - 27	27
CDR-H1	DYAMA	28 - 32	5
HFR2	WFRQAPGKEREFVA	33 - 46	14
CDR-H2	RSGGSTDYADSVKG	47 - 60	14
HFR3	RFTISRDNAKSTVYLQMNSLRPEDTAVYYCAG	61 - 92	32
CDR-H3	DLGWARVRRLITRPEMYDY	93 - 111	19
HFR4	WGQGTQVT	112 - 119	8
			119

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGGSLRLSCVAS-----	1 - 22	22
	AbM	LQESGGGLVQAGGSLRLSCVAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGGSLRLSCVASGITFS	1 - 27	27
	Contact	LQESGGGLVQAGGSLRLSCVASGITF-	1 - 26	26
	IMGT	LQESGGGLVQAGGSLRLSCVAS-----	1 - 22	22
CDR-H1	Chothia	GITFSDY---	23 - 29	7
	AbM	GITFSDYAMA	23 - 32	10
	Kabat	-----DYAMA	28 - 32	5
	Contact	----SDYAMA	27 - 32	6
	IMGT	GITFSDYA--	23 - 30	8
HFR2	Chothia	AMAWFRQAPGKEREFVARS	30 - 48	19
	AbM	---WFRQAPGKEREFVA--	33 - 46	14
	Kabat	---WFRQAPGKEREFVA--	33 - 46	14
	Contact	---WFRQAPGKERE-----	33 - 43	11
	IMGT	-MAWFRQAPGKEREFVAR-	31 - 47	17
CDR-H2	Chothia	-----GGS---------	49 - 51	3
	AbM	---RSGGSTD-------	47 - 53	7
	Kabat	---RSGGSTDYADSVKG	47 - 60	14
	Contact	FVARSGGSTD-------	44 - 53	10
	IMGT	----SGGST--------	48 - 52	5
HFR3	Chothia	TDYADSVKGRFTISRDNAKSTVYLQMNSLRPEDTAVYYCAG	52 - 92	41
	AbM	--YADSVKGRFTISRDNAKSTVYLQMNSLRPEDTAVYYCAG	54 - 92	39
	Kabat	---------RFTISRDNAKSTVYLQMNSLRPEDTAVYYCAG	61 - 92	32
	Contact	--YADSVKGRFTISRDNAKSTVYLQMNSLRPEDTAVYYC--	54 - 90	37
	IMGT	-DYADSVKGRFTISRDNAKSTVYLQMNSLRPEDTAVYYC--	53 - 90	38
CDR-H3	Chothia	--DLGWARVRRLITRPEMYDY	93 - 111	19
	AbM	--DLGWARVRRLITRPEMYDY	93 - 111	19
	Kabat	--DLGWARVRRLITRPEMYDY	93 - 111	19
	Contact	AGDLGWARVRRLITRPEMYD-	91 - 110	20
	IMGT	AGDLGWARVRRLITRPEMYDY	91 - 111	21
HFR4	Chothia	-WGQGTQVT	112 - 119	8
	AbM	-WGQGTQVT	112 - 119	8
	Kabat	-WGQGTQVT	112 - 119	8
	Contact	YWGQGTQVT	111 - 119	9
	IMGT	-WGQGTQVT	112 - 119	8

Accession & Annotations

Accession	CAH18852.1
Source	abYsis-EMBL-IG AJ811556 Submitted 20-AUG-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	M177
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (19-AUG-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., Van Solt C.B., Van Keulen L. 'Selection of llama single-domain antibody fragments binding to recombinant bovine prion protein in ELISA' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGGSLRLSCVASGITFSDYAMAWFRQAPGKEREFVARSGGSTDYADSVKG
RFTISRDNAKSTVYLQMNSLRPEDTAVYYCAGDLGWARVRRLITRPEMYDYWGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggattggtgcaggctgggggctctctgagactctcctgtgta
gcctctggcatcaccttcagcgactatgccatggcctggttccgccaggctccggggaag
gagcgtgagtttgtagcacggagtggcgggagcaccgactatgcagactccgtgaagggc
cgattcaccatctccagagacaacgccaagagtacggtgtatttgcagatgaacagcctg
agacctgaggacacggccgtttattactgcgcgggagatcttggctgggctcgtgttagg
cgcctcataacgcggcccgagatgtacgactactggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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