abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQPGGSLRLSCVASGTIFS	1 - 27	27
CDR-H1	INDISINHLG	28 - 37	10
HFR2	WYRQAPGKERELVA	38 - 51	14
CDR-H2	AITADGTSAYEDSVKG	52 - 67	16
HFR3	RFIISRDDAKKMVYLQMNNLKPEDTAVYYCNG	68 - 99	32
CDR-H3	LRASNAGWEPRFGT	100 - 113	14
HFR4	WGQGTQVT	114 - 121	8
			121

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQPGGSLRLSCVAS-----	1 - 22	22
	AbM	LQESGGGLVQPGGSLRLSCVAS-----	1 - 22	22
	Kabat	LQESGGGLVQPGGSLRLSCVASGTIFS	1 - 27	27
	Contact	LQESGGGLVQPGGSLRLSCVASGTIF-	1 - 26	26
	IMGT	LQESGGGLVQPGGSLRLSCVAS-----	1 - 22	22
CDR-H1	Chothia	GTIFSINDISIN---	23 - 34	12
	AbM	GTIFSINDISINHLG	23 - 37	15
	Kabat	-----INDISINHLG	28 - 37	10
	Contact	----SINDISINHLG	27 - 37	11
	IMGT	GTIFSINDISINH--	23 - 35	13
HFR2	Chothia	HLGWYRQAPGKERELVAAI	35 - 53	19
	AbM	---WYRQAPGKERELVA--	38 - 51	14
	Kabat	---WYRQAPGKERELVA--	38 - 51	14
	Contact	---WYRQAPGKERE-----	38 - 48	11
	IMGT	-LGWYRQAPGKERELVAA-	36 - 52	17
CDR-H2	Chothia	-----TADGT---------	54 - 58	5
	AbM	---AITADGTSA-------	52 - 60	9
	Kabat	---AITADGTSAYEDSVKG	52 - 67	16
	Contact	LVAAITADGTSA-------	49 - 60	12
	IMGT	----ITADGTS--------	53 - 59	7
HFR3	Chothia	SAYEDSVKGRFIISRDDAKKMVYLQMNNLKPEDTAVYYCNG	59 - 99	41
	AbM	--YEDSVKGRFIISRDDAKKMVYLQMNNLKPEDTAVYYCNG	61 - 99	39
	Kabat	---------RFIISRDDAKKMVYLQMNNLKPEDTAVYYCNG	68 - 99	32
	Contact	--YEDSVKGRFIISRDDAKKMVYLQMNNLKPEDTAVYYC--	61 - 97	37
	IMGT	-AYEDSVKGRFIISRDDAKKMVYLQMNNLKPEDTAVYYC--	60 - 97	38
CDR-H3	Chothia	--LRASNAGWEPRFGT	100 - 113	14
	AbM	--LRASNAGWEPRFGT	100 - 113	14
	Kabat	--LRASNAGWEPRFGT	100 - 113	14
	Contact	NGLRASNAGWEPRFG-	98 - 112	15
	IMGT	NGLRASNAGWEPRFGT	98 - 113	16
HFR4	Chothia	-WGQGTQVT	114 - 121	8
	AbM	-WGQGTQVT	114 - 121	8
	Kabat	-WGQGTQVT	114 - 121	8
	Contact	TWGQGTQVT	113 - 121	9
	IMGT	-WGQGTQVT	114 - 121	8

Accession & Annotations

Accession	CAH18857.1
Source	abYsis-EMBL-IG AJ811561 Submitted 20-AUG-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	M191
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (19-AUG-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., Van Solt C.B., Van Keulen L. 'Selection of llama single-domain antibody fragments binding to recombinant bovine prion protein in ELISA' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQPGGSLRLSCVASGTIFSINDISINHLGWYRQAPGKERELVAAITADGTSA
YEDSVKGRFIISRDDAKKMVYLQMNNLKPEDTAVYYCNGLRASNAGWEPRFGTWGQGTQV
T

DNA Sequence:

ctgcaggagtctgggggaggcttggtgcagcctggggggtctctgagactctcctgtgta
gcctctggaacgatcttcagtatcaatgacatcagtatcaatcacctgggctggtaccgc
caggctccagggaaggaacgcgagttggtcgcggctatcactgctgatggtacatcagcc
tatgaagactccgtgaagggccgattcatcatctccagagacgacgccaaaaagatggtg
tatctgcaaatgaacaacctgaaacccgaggacacggccgtctattactgtaatggtcta
agggcctcgaatgcgggttgggagccccgctttggtacttggggccaggggacccaggtc
acc

Data Source:

Alignment settings:

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