abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGSLVQPGGSLRLSCVASGSSVS	1 - 27	27
CDR-H1	INHMG	28 - 32	5
HFR2	WYRQAPGKERELVA	33 - 46	14
CDR-H2	AITSDGESAYEDSVKG	47 - 62	16
HFR3	RFAISRDNLKNMVYLQMNTLKAEDTAMYYCNY	63 - 94	32
CDR-H3	LRATSAGWELRFGS	95 - 108	14
HFR4	WGQGTQVT	109 - 116	8
			116

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGSLVQPGGSLRLSCVAS-----	1 - 22	22
	AbM	LQESGGSLVQPGGSLRLSCVAS-----	1 - 22	22
	Kabat	LQESGGSLVQPGGSLRLSCVASGSSVS	1 - 27	27
	Contact	LQESGGSLVQPGGSLRLSCVASGSSV-	1 - 26	26
	IMGT	LQESGGSLVQPGGSLRLSCVAS-----	1 - 22	22
CDR-H1	Chothia	GSSVSIN---	23 - 29	7
	AbM	GSSVSINHMG	23 - 32	10
	Kabat	-----INHMG	28 - 32	5
	Contact	----SINHMG	27 - 32	6
	IMGT	GSSVSINH--	23 - 30	8
HFR2	Chothia	HMGWYRQAPGKERELVAAI	30 - 48	19
	AbM	---WYRQAPGKERELVA--	33 - 46	14
	Kabat	---WYRQAPGKERELVA--	33 - 46	14
	Contact	---WYRQAPGKERE-----	33 - 43	11
	IMGT	-MGWYRQAPGKERELVAA-	31 - 47	17
CDR-H2	Chothia	-----TSDGE---------	49 - 53	5
	AbM	---AITSDGESA-------	47 - 55	9
	Kabat	---AITSDGESAYEDSVKG	47 - 62	16
	Contact	LVAAITSDGESA-------	44 - 55	12
	IMGT	----ITSDGES--------	48 - 54	7
HFR3	Chothia	SAYEDSVKGRFAISRDNLKNMVYLQMNTLKAEDTAMYYCNY	54 - 94	41
	AbM	--YEDSVKGRFAISRDNLKNMVYLQMNTLKAEDTAMYYCNY	56 - 94	39
	Kabat	---------RFAISRDNLKNMVYLQMNTLKAEDTAMYYCNY	63 - 94	32
	Contact	--YEDSVKGRFAISRDNLKNMVYLQMNTLKAEDTAMYYC--	56 - 92	37
	IMGT	-AYEDSVKGRFAISRDNLKNMVYLQMNTLKAEDTAMYYC--	55 - 92	38
CDR-H3	Chothia	--LRATSAGWELRFGS	95 - 108	14
	AbM	--LRATSAGWELRFGS	95 - 108	14
	Kabat	--LRATSAGWELRFGS	95 - 108	14
	Contact	NYLRATSAGWELRFG-	93 - 107	15
	IMGT	NYLRATSAGWELRFGS	93 - 108	16
HFR4	Chothia	-WGQGTQVT	109 - 116	8
	AbM	-WGQGTQVT	109 - 116	8
	Kabat	-WGQGTQVT	109 - 116	8
	Contact	SWGQGTQVT	108 - 116	9
	IMGT	-WGQGTQVT	109 - 116	8

Accession & Annotations

Accession	CAH18858.1
Source	abYsis-EMBL-IG AJ811562 Submitted 20-AUG-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	M194
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (19-AUG-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., Van Solt C.B., Van Keulen L. 'Selection of llama single-domain antibody fragments binding to recombinant bovine prion protein in ELISA' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGSLVQPGGSLRLSCVASGSSVSINHMGWYRQAPGKERELVAAITSDGESAYEDSV
KGRFAISRDNLKNMVYLQMNTLKAEDTAMYYCNYLRATSAGWELRFGSWGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaagcttggtgcagcctggggggtctctgagactctcctgtgta
gcctctggaagcagcgtcagtatcaatcacatgggctggtaccgccaggctccagggaag
gagcgcgagttggtcgcggcaatcaccagtgatggtgaatcagcctatgaagactccgtg
aagggccgattcgccatctccagagacaacctcaagaatatggtgtatctgcaaatgaac
actctgaaagccgaggacacggccatgtattactgtaattatctaagggccacgagtgcg
ggttgggagctccgattcggttcctggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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