abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQPGGSLRLSCVASGINSR	1 - 27	27
CDR-H1	IYRTG	28 - 32	5
HFR2	WYRQAPGNQRELVA	33 - 46	14
CDR-H2	RISDGGSTNYGDSVKG	47 - 62	16
HFR3	RFTISRDNAKNTVYLQMNNLKPEDTAVYQCCV	63 - 94	32
CDR-H3	NTVANLGRNY	95 - 104	10
HFR4	CGQGTQVT	105 - 112	8
			112

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQPGGSLRLSCVAS-----	1 - 22	22
	AbM	LQESGGGLVQPGGSLRLSCVAS-----	1 - 22	22
	Kabat	LQESGGGLVQPGGSLRLSCVASGINSR	1 - 27	27
	Contact	LQESGGGLVQPGGSLRLSCVASGINS-	1 - 26	26
	IMGT	LQESGGGLVQPGGSLRLSCVAS-----	1 - 22	22
CDR-H1	Chothia	GINSRIY---	23 - 29	7
	AbM	GINSRIYRTG	23 - 32	10
	Kabat	-----IYRTG	28 - 32	5
	Contact	----RIYRTG	27 - 32	6
	IMGT	GINSRIYR--	23 - 30	8
HFR2	Chothia	RTGWYRQAPGNQRELVARI	30 - 48	19
	AbM	---WYRQAPGNQRELVA--	33 - 46	14
	Kabat	---WYRQAPGNQRELVA--	33 - 46	14
	Contact	---WYRQAPGNQRE-----	33 - 43	11
	IMGT	-TGWYRQAPGNQRELVAR-	31 - 47	17
CDR-H2	Chothia	-----SDGGS---------	49 - 53	5
	AbM	---RISDGGSTN-------	47 - 55	9
	Kabat	---RISDGGSTNYGDSVKG	47 - 62	16
	Contact	LVARISDGGSTN-------	44 - 55	12
	IMGT	----ISDGGST--------	48 - 54	7
HFR3	Chothia	TNYGDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYQCCV	54 - 94	41
	AbM	--YGDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYQCCV	56 - 94	39
	Kabat	---------RFTISRDNAKNTVYLQMNNLKPEDTAVYQCCV	63 - 94	32
	Contact	--YGDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYQC--	56 - 92	37
	IMGT	-NYGDSVKGRFTISRDNAKNTVYLQMNNLKPEDTAVYQC--	55 - 92	38
CDR-H3	Chothia	--NTVANLGRNY	95 - 104	10
	AbM	--NTVANLGRNY	95 - 104	10
	Kabat	--NTVANLGRNY	95 - 104	10
	Contact	CVNTVANLGRN-	93 - 103	11
	IMGT	CVNTVANLGRNY	93 - 104	12
HFR4	Chothia	-CGQGTQVT	105 - 112	8
	AbM	-CGQGTQVT	105 - 112	8
	Kabat	-CGQGTQVT	105 - 112	8
	Contact	YCGQGTQVT	104 - 112	9
	IMGT	-CGQGTQVT	105 - 112	8

Accession & Annotations

Accession	CAH60934.1
Source	abYsis-EMBL-IG AJ849419 Submitted 12-OCT-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	LT128
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (12-OCT-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M. 'Selection of llama single-domain antibody fragments binding to Escherichi a coli heat-labile enterotoxin' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQPGGSLRLSCVASGINSRIYRTGWYRQAPGNQRELVARISDGGSTNYGDSV
KGRFTISRDNAKNTVYLQMNNLKPEDTAVYQCCVNTVANLGRNYCGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggcttggtgcagcctggggggtctctgagactctcctgtgta
gcctctggaatcaactcccgtatctatcgcaccggctggtaccgccaggctccagggaat
cagcgcgagttggtcgcacgtattagtgatggtggtagtacaaactatggagactccgtg
aagggccgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaac
aacctgaaacctgaggacacggccgtctatcagtgttgtgtaaatactgttgccaacttg
gggagaaattactgcggccaggggacccaggtcacc

Data Source:

Alignment settings:

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