abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGDSLRLSCVASGRA	1 - 25	25
CDR-H1	FTVA	26 - 29	4
HFR2	WFRQAPGKEREFVS	30 - 43	14
CDR-H2	GIRWIGSSTLYADSVKG	44 - 60	17
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	61 - 92	32
CDR-H3	TRALAIATTSEKYDY	93 - 107	15
HFR4	WGQGTQVT	108 - 115	8
			115

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGDSLRLSCVAS---	1 - 22	22
	AbM	LQESGGGLVQAGDSLRLSCVAS---	1 - 22	22
	Kabat	LQESGGGLVQAGDSLRLSCVASGRA	1 - 25	25
	Contact	LQESGGGLVQAGDSLRLSCVASGRA	1 - 25	25
	IMGT	LQESGGGLVQAGDSLRLSCVAS---	1 - 22	22
CDR-H1	Chothia	GRAF---	23 - 26	4
	AbM	GRAFTVA	23 - 29	7
	Kabat	---FTVA	26 - 29	4
	Contact	---FTVA	26 - 29	4
	IMGT	GRAFT--	23 - 27	5
HFR2	Chothia	TVAWFRQAPGKEREFVSGI	27 - 45	19
	AbM	---WFRQAPGKEREFVS--	30 - 43	14
	Kabat	---WFRQAPGKEREFVS--	30 - 43	14
	Contact	---WFRQAPGKERE-----	30 - 40	11
	IMGT	-VAWFRQAPGKEREFVSG-	28 - 44	17
CDR-H2	Chothia	-----RWIGSS---------	46 - 51	6
	AbM	---GIRWIGSSTL-------	44 - 53	10
	Kabat	---GIRWIGSSTLYADSVKG	44 - 60	17
	Contact	FVSGIRWIGSSTL-------	41 - 53	13
	IMGT	----IRWIGSST--------	45 - 52	8
HFR3	Chothia	TLYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	52 - 92	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	54 - 92	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	61 - 92	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	54 - 90	37
	IMGT	-LYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	53 - 90	38
CDR-H3	Chothia	--TRALAIATTSEKYDY	93 - 107	15
	AbM	--TRALAIATTSEKYDY	93 - 107	15
	Kabat	--TRALAIATTSEKYDY	93 - 107	15
	Contact	AATRALAIATTSEKYD-	91 - 106	16
	IMGT	AATRALAIATTSEKYDY	91 - 107	17
HFR4	Chothia	-WGQGTQVT	108 - 115	8
	AbM	-WGQGTQVT	108 - 115	8
	Kabat	-WGQGTQVT	108 - 115	8
	Contact	YWGQGTQVT	107 - 115	9
	IMGT	-WGQGTQVT	108 - 115	8

Accession & Annotations

Accession	CAH60938.1
Source	abYsis-EMBL-IG AJ849423 Submitted 12-OCT-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	LT132
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (12-OCT-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M. 'Selection of llama single-domain antibody fragments binding to Escherichi a coli heat-labile enterotoxin' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGDSLRLSCVASGRAFTVAWFRQAPGKEREFVSGIRWIGSSTLYADSVKG
RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAATRALAIATTSEKYDYWGQGTQVT

DNA Sequence:

ctgcaggagtcagggggaggattggtgcaggctggagactctctcagactctcctgtgta
gcctctggacgcgccttcactgtggcttggttccgccaggctccagggaaggagcgtgag
tttgtatcaggtattagatggattggtagtagtacattgtatgcagactccgtgaagggc
cgattcaccatctccagagacaacgccaagaacacggtgtatctgcaaatgaacagcctg
aaacctgaggacacggccgtctattactgtgcagcaacccgggctttagcgatcgctact
acttccgaaaaatatgactactggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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