abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGGSLRLSCAASGRTVS	1 - 27	27
CDR-H1	SKAMG	28 - 32	5
HFR2	WFRQAPGKEREFVG	33 - 46	14
CDR-H2	SISWGGHSANYRDSVEG	47 - 63	17
HFR3	RFTISRDDSKNTVYLQMNSLKPEDTAVYYCAA	64 - 95	32
CDR-H3	STGSQATMSFRSYGS	96 - 110	15
HFR4	WGQGTQVT	111 - 118	8
			118

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGGSLRLSCAASGRTVS	1 - 27	27
	Contact	LQESGGGLVQAGGSLRLSCAASGRTV-	1 - 26	26
	IMGT	LQESGGGLVQAGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GRTVSSK---	23 - 29	7
	AbM	GRTVSSKAMG	23 - 32	10
	Kabat	-----SKAMG	28 - 32	5
	Contact	----SSKAMG	27 - 32	6
	IMGT	GRTVSSKA--	23 - 30	8
HFR2	Chothia	AMGWFRQAPGKEREFVGSI	30 - 48	19
	AbM	---WFRQAPGKEREFVG--	33 - 46	14
	Kabat	---WFRQAPGKEREFVG--	33 - 46	14
	Contact	---WFRQAPGKERE-----	33 - 43	11
	IMGT	-MGWFRQAPGKEREFVGS-	31 - 47	17
CDR-H2	Chothia	-----SWGGHS---------	49 - 54	6
	AbM	---SISWGGHSAN-------	47 - 56	10
	Kabat	---SISWGGHSANYRDSVEG	47 - 63	17
	Contact	FVGSISWGGHSAN-------	44 - 56	13
	IMGT	----ISWGGHSA--------	48 - 55	8
HFR3	Chothia	ANYRDSVEGRFTISRDDSKNTVYLQMNSLKPEDTAVYYCAA	55 - 95	41
	AbM	--YRDSVEGRFTISRDDSKNTVYLQMNSLKPEDTAVYYCAA	57 - 95	39
	Kabat	---------RFTISRDDSKNTVYLQMNSLKPEDTAVYYCAA	64 - 95	32
	Contact	--YRDSVEGRFTISRDDSKNTVYLQMNSLKPEDTAVYYC--	57 - 93	37
	IMGT	-NYRDSVEGRFTISRDDSKNTVYLQMNSLKPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--STGSQATMSFRSYGS	96 - 110	15
	AbM	--STGSQATMSFRSYGS	96 - 110	15
	Kabat	--STGSQATMSFRSYGS	96 - 110	15
	Contact	AASTGSQATMSFRSYG-	94 - 109	16
	IMGT	AASTGSQATMSFRSYGS	94 - 110	17
HFR4	Chothia	-WGQGTQVT	111 - 118	8
	AbM	-WGQGTQVT	111 - 118	8
	Kabat	-WGQGTQVT	111 - 118	8
	Contact	SWGQGTQVT	110 - 118	9
	IMGT	-WGQGTQVT	111 - 118	8

Accession & Annotations

Accession	CAJ55286.1
Source	abYsis-EMBL-IG AM180292 Submitted 20-DEC-2005 Updated 27-FEB-2007
Name	immunoglobulin heavy chain variable region
Clone	M92
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (16-DEC-2005) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., van Solt C.B., Fijten H.P.D., van Keulen L., Rosalia R.A., Weerdmeester K., Cornelissen .A.H.M., De Bruin M.G.M., Eble P.L., Dekker A. 'Passive immunization of guinea pigs with llama single-domain antibody fragments against foot-and-mouth disease' Vet. Microbiol. 120(3-4):193-206(2007).

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGGSLRLSCAASGRTVSSKAMGWFRQAPGKEREFVGSISWGGHSANYRDS
VEGRFTISRDDSKNTVYLQMNSLKPEDTAVYYCAASTGSQATMSFRSYGSWGQGTQVT

DNA Sequence:

ctgcaggagtcagggggaggattggtgcaggctgggggctctctgagactctcctgtgca
gcctctggacgcaccgtcagtagtaaagccatgggctggttccgccaggctccagggaag
gagcgtgaatttgtaggaagcattagttggggtggtcattcggcaaattatagagactcc
gtggagggccgattcaccatctccagagacgactccaagaacacggtgtatctacaaatg
aacagcctgaaacccgaggacacggccgtttattactgtgcagcgtccacagggtctcag
gcaacaatgagcttccggagctatggctcgtggggccaggggacccaggtcacc

Data Source:

Alignment settings:

Search settings: