abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGLVQAGDPLTLSCAASGRTVE	1 - 27	27
CDR-H1	NYAMG	28 - 32	5
HFR2	WFRQTPGKEPEFVA	33 - 46	14
CDR-H2	AISWWSGSRADYSDSVKG	47 - 64	18
HFR3	RFTISRDNAKKTLYLQMSSLQPEDTGVYYCAA	65 - 96	32
CDR-H3	EPGTYFAGRFESEYDY	97 - 112	16
HFR4	WGQGTLVT	113 - 120	8
			120

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGLVQAGDPLTLSCAAS-----	1 - 22	22
	AbM	LQQSGGGLVQAGDPLTLSCAAS-----	1 - 22	22
	Kabat	LQQSGGGLVQAGDPLTLSCAASGRTVE	1 - 27	27
	Contact	LQQSGGGLVQAGDPLTLSCAASGRTV-	1 - 26	26
	IMGT	LQQSGGGLVQAGDPLTLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GRTVENY---	23 - 29	7
	AbM	GRTVENYAMG	23 - 32	10
	Kabat	-----NYAMG	28 - 32	5
	Contact	----ENYAMG	27 - 32	6
	IMGT	GRTVENYA--	23 - 30	8
HFR2	Chothia	AMGWFRQTPGKEPEFVAAI	30 - 48	19
	AbM	---WFRQTPGKEPEFVA--	33 - 46	14
	Kabat	---WFRQTPGKEPEFVA--	33 - 46	14
	Contact	---WFRQTPGKEPE-----	33 - 43	11
	IMGT	-MGWFRQTPGKEPEFVAA-	31 - 47	17
CDR-H2	Chothia	-----SWWSGSR---------	49 - 55	7
	AbM	---AISWWSGSRAD-------	47 - 57	11
	Kabat	---AISWWSGSRADYSDSVKG	47 - 64	18
	Contact	FVAAISWWSGSRAD-------	44 - 57	14
	IMGT	----ISWWSGSRA--------	48 - 56	9
HFR3	Chothia	ADYSDSVKGRFTISRDNAKKTLYLQMSSLQPEDTGVYYCAA	56 - 96	41
	AbM	--YSDSVKGRFTISRDNAKKTLYLQMSSLQPEDTGVYYCAA	58 - 96	39
	Kabat	---------RFTISRDNAKKTLYLQMSSLQPEDTGVYYCAA	65 - 96	32
	Contact	--YSDSVKGRFTISRDNAKKTLYLQMSSLQPEDTGVYYC--	58 - 94	37
	IMGT	-DYSDSVKGRFTISRDNAKKTLYLQMSSLQPEDTGVYYC--	57 - 94	38
CDR-H3	Chothia	--EPGTYFAGRFESEYDY	97 - 112	16
	AbM	--EPGTYFAGRFESEYDY	97 - 112	16
	Kabat	--EPGTYFAGRFESEYDY	97 - 112	16
	Contact	AAEPGTYFAGRFESEYD-	95 - 111	17
	IMGT	AAEPGTYFAGRFESEYDY	95 - 112	18
HFR4	Chothia	-WGQGTLVT	113 - 120	8
	AbM	-WGQGTLVT	113 - 120	8
	Kabat	-WGQGTLVT	113 - 120	8
	Contact	YWGQGTLVT	112 - 120	9
	IMGT	-WGQGTLVT	113 - 120	8

Accession & Annotations

Accession	CAJ55296.1
Source	abYsis-EMBL-IG AM180302 Submitted 20-DEC-2005 Updated 27-FEB-2007
Name	immunoglobulin heavy chain variable region
Clone	M81
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (16-DEC-2005) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., van Solt C.B., Fijten H.P.D., van Keulen L., Rosalia R.A., Weerdmeester K., Cornelissen .A.H.M., De Bruin M.G.M., Eble P.L., Dekker A. 'Passive immunization of guinea pigs with llama single-domain antibody fragments against foot-and-mouth disease' Vet. Microbiol. 120(3-4):193-206(2007).

Tools

Sequences

Amino Acid Sequence:

LQQSGGGLVQAGDPLTLSCAASGRTVENYAMGWFRQTPGKEPEFVAAISWWSGSRADYSD
SVKGRFTISRDNAKKTLYLQMSSLQPEDTGVYYCAAEPGTYFAGRFESEYDYWGQGTLVT

DNA Sequence:

ctgcagcagtcagggggaggtttggtgcaggctggggaccctctgacactctcctgtgca
gcctctggacgcacggtcgagaactatgccatgggctggttccgccagactccaggaaag
gagcctgagtttgtagcggctattagctggtggagtggtagtagggcagactattcagac
tccgtgaagggccgattcaccatctccagagacaacgccaagaaaacactgtacctgcaa
atgagcagcctccaacctgaggacacgggcgtttattactgtgcagcagagcctggtact
tacttcgccgggagatttgaatctgagtatgactactggggccaggggaccctagtcacc

Data Source:

Alignment settings:

Search settings: