abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQTGGSLRLSCAASGFTFS	1 - 27	27
CDR-H1	SNWMY	28 - 32	5
HFR2	WVRQAPGKGLEWVS	33 - 46	14
CDR-H2	IIEADGSATYYTPSVKG	47 - 63	17
HFR3	RFTISRDNVKNTLYLQMNSLKPEDTALYYCAR	64 - 95	32
CDR-H3	DQDGRV	96 - 101	6
HFR4	RGQGTQVT	102 - 109	8
			109

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQTGGSLRLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQTGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQTGGSLRLSCAASGFTFS	1 - 27	27
	Contact	LQESGGGLVQTGGSLRLSCAASGFTF-	1 - 26	26
	IMGT	LQESGGGLVQTGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GFTFSSN---	23 - 29	7
	AbM	GFTFSSNWMY	23 - 32	10
	Kabat	-----SNWMY	28 - 32	5
	Contact	----SSNWMY	27 - 32	6
	IMGT	GFTFSSNW--	23 - 30	8
HFR2	Chothia	WMYWVRQAPGKGLEWVSII	30 - 48	19
	AbM	---WVRQAPGKGLEWVS--	33 - 46	14
	Kabat	---WVRQAPGKGLEWVS--	33 - 46	14
	Contact	---WVRQAPGKGLE-----	33 - 43	11
	IMGT	-MYWVRQAPGKGLEWVSI-	31 - 47	17
CDR-H2	Chothia	-----EADGSA---------	49 - 54	6
	AbM	---IIEADGSATY-------	47 - 56	10
	Kabat	---IIEADGSATYYTPSVKG	47 - 63	17
	Contact	WVSIIEADGSATY-------	44 - 56	13
	IMGT	----IEADGSAT--------	48 - 55	8
HFR3	Chothia	TYYTPSVKGRFTISRDNVKNTLYLQMNSLKPEDTALYYCAR	55 - 95	41
	AbM	--YTPSVKGRFTISRDNVKNTLYLQMNSLKPEDTALYYCAR	57 - 95	39
	Kabat	---------RFTISRDNVKNTLYLQMNSLKPEDTALYYCAR	64 - 95	32
	Contact	--YTPSVKGRFTISRDNVKNTLYLQMNSLKPEDTALYYC--	57 - 93	37
	IMGT	-YYTPSVKGRFTISRDNVKNTLYLQMNSLKPEDTALYYC--	56 - 93	38
CDR-H3	Chothia	--DQDGRV	96 - 101	6
	AbM	--DQDGRV	96 - 101	6
	Kabat	--DQDGRV	96 - 101	6
	Contact	ARDQDGR-	94 - 100	7
	IMGT	ARDQDGRV	94 - 101	8
HFR4	Chothia	-RGQGTQVT	102 - 109	8
	AbM	-RGQGTQVT	102 - 109	8
	Kabat	-RGQGTQVT	102 - 109	8
	Contact	VRGQGTQVT	101 - 109	9
	IMGT	-RGQGTQVT	102 - 109	8

Accession & Annotations

Accession	CAJ55298.1
Source	abYsis-EMBL-IG AM180305 Submitted 20-DEC-2005 Updated 27-FEB-2007
Name	immunoglobulin heavy chain variable region
Clone	M86
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (16-DEC-2005) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., van Solt C.B., Fijten H.P.D., van Keulen L., Rosalia R.A., Weerdmeester K., Cornelissen .A.H.M., De Bruin M.G.M., Eble P.L., Dekker A. 'Passive immunization of guinea pigs with llama single-domain antibody fragments against foot-and-mouth disease' Vet. Microbiol. 120(3-4):193-206(2007).

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQTGGSLRLSCAASGFTFSSNWMYWVRQAPGKGLEWVSIIEADGSATYYTPS
VKGRFTISRDNVKNTLYLQMNSLKPEDTALYYCARDQDGRVRGQGTQVT

DNA Sequence:

ctgcaggagtctgggggaggattggtgcagactgggggctctctgagactctcctgtgcg
gcctctggattcaccttcagtagcaactggatgtattgggtccgtcaggctccagggaag
ggactcgagtgggtctcaattattgaagctgatggtagtgccacatactatacaccctcc
gtgaagggccgattcaccatctccagagacaatgtcaagaatacgctgtatctgcaaatg
aacagcctgaaacctgaggacacggccctgtattactgtgcgagagatcaagacggtcgt
gtccggggccaggggacccaggtcacc

Data Source:

Alignment settings:

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