abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGLVQPGGSLRLSCAASGFTFS	1 - 27	27
CDR-H1	HYWMY	28 - 32	5
HFR2	WVRQAPGKGLEWVS	33 - 46	14
CDR-H2	SISNGGGTYYSDSVKG	47 - 62	16
HFR3	RFSISRDNAKNTLYLQMNSLKPEDTALYYCAR	63 - 94	32
CDR-H3	RRGGTNYFVGVIGGIPEYDY	95 - 114	20
HFR4	RGQGTQVT	115 - 122	8
			122

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGLVQPGGSLRLSCAAS-----	1 - 22	22
	AbM	LQQSGGGLVQPGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQQSGGGLVQPGGSLRLSCAASGFTFS	1 - 27	27
	Contact	LQQSGGGLVQPGGSLRLSCAASGFTF-	1 - 26	26
	IMGT	LQQSGGGLVQPGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GFTFSHY---	23 - 29	7
	AbM	GFTFSHYWMY	23 - 32	10
	Kabat	-----HYWMY	28 - 32	5
	Contact	----SHYWMY	27 - 32	6
	IMGT	GFTFSHYW--	23 - 30	8
HFR2	Chothia	WMYWVRQAPGKGLEWVSSI	30 - 48	19
	AbM	---WVRQAPGKGLEWVS--	33 - 46	14
	Kabat	---WVRQAPGKGLEWVS--	33 - 46	14
	Contact	---WVRQAPGKGLE-----	33 - 43	11
	IMGT	-MYWVRQAPGKGLEWVSS-	31 - 47	17
CDR-H2	Chothia	-----SNGGG---------	49 - 53	5
	AbM	---SISNGGGTY-------	47 - 55	9
	Kabat	---SISNGGGTYYSDSVKG	47 - 62	16
	Contact	WVSSISNGGGTY-------	44 - 55	12
	IMGT	----ISNGGGT--------	48 - 54	7
HFR3	Chothia	TYYSDSVKGRFSISRDNAKNTLYLQMNSLKPEDTALYYCAR	54 - 94	41
	AbM	--YSDSVKGRFSISRDNAKNTLYLQMNSLKPEDTALYYCAR	56 - 94	39
	Kabat	---------RFSISRDNAKNTLYLQMNSLKPEDTALYYCAR	63 - 94	32
	Contact	--YSDSVKGRFSISRDNAKNTLYLQMNSLKPEDTALYYC--	56 - 92	37
	IMGT	-YYSDSVKGRFSISRDNAKNTLYLQMNSLKPEDTALYYC--	55 - 92	38
CDR-H3	Chothia	--RRGGTNYFVGVIGGIPEYDY	95 - 114	20
	AbM	--RRGGTNYFVGVIGGIPEYDY	95 - 114	20
	Kabat	--RRGGTNYFVGVIGGIPEYDY	95 - 114	20
	Contact	ARRRGGTNYFVGVIGGIPEYD-	93 - 113	21
	IMGT	ARRRGGTNYFVGVIGGIPEYDY	93 - 114	22
HFR4	Chothia	-RGQGTQVT	115 - 122	8
	AbM	-RGQGTQVT	115 - 122	8
	Kabat	-RGQGTQVT	115 - 122	8
	Contact	YRGQGTQVT	114 - 122	9
	IMGT	-RGQGTQVT	115 - 122	8

Accession & Annotations

Accession	CAJ55301.1
Source	abYsis-EMBL-IG AM180310 Submitted 20-DEC-2005 Updated 27-FEB-2007
Name	immunoglobulin heavy chain variable region
Clone	M129
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (16-DEC-2005) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., van Solt C.B., Fijten H.P.D., van Keulen L., Rosalia R.A., Weerdmeester K., Cornelissen .A.H.M., De Bruin M.G.M., Eble P.L., Dekker A. 'Passive immunization of guinea pigs with llama single-domain antibody fragments against foot-and-mouth disease' Vet. Microbiol. 120(3-4):193-206(2007).

Tools

Sequences

Amino Acid Sequence:

LQQSGGGLVQPGGSLRLSCAASGFTFSHYWMYWVRQAPGKGLEWVSSISNGGGTYYSDSV
KGRFSISRDNAKNTLYLQMNSLKPEDTALYYCARRRGGTNYFVGVIGGIPEYDYRGQGTQ
VT

DNA Sequence:

ctgcagcagtctgggggaggcttggtgcagcctggggggtctctgagactctcctgtgca
gcctctggattcaccttcagtcactattggatgtattgggtccgtcaggctccagggaag
gggctcgagtgggtctcaagtattagcaatggtggcgggacatactattcggactccgtg
aagggccgattctccatctccagagacaacgccaagaacacactgtatctgcaaatgaac
agcctgaaacctgaggacacggccctgtattactgtgcgagacgtcggggtggtactaac
tactttgtcggcgtaattggcggcataccagaatatgactaccggggccaggggacccag
gtcacc

Data Source:

Alignment settings:

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