abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQQSGGGLVQPGGSLRLSCAASGFTFS	1 - 27	27
CDR-H1	RDAMS	28 - 32	5
HFR2	WVRQAPGKGLEWVS	33 - 46	14
CDR-H2	SIVASGRDTRYADSVKG	47 - 63	17
HFR3	RFTISRDNAKNTLYLQMNSLRPEDTAVYYCTK	64 - 95	32
CDR-H3	TPKSDTDWST	96 - 105	10
HFR4	PGQGTQVI	106 - 113	8
			113

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQQSGGGLVQPGGSLRLSCAAS-----	1 - 22	22
	AbM	LQQSGGGLVQPGGSLRLSCAAS-----	1 - 22	22
	Kabat	LQQSGGGLVQPGGSLRLSCAASGFTFS	1 - 27	27
	Contact	LQQSGGGLVQPGGSLRLSCAASGFTF-	1 - 26	26
	IMGT	LQQSGGGLVQPGGSLRLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GFTFSRD---	23 - 29	7
	AbM	GFTFSRDAMS	23 - 32	10
	Kabat	-----RDAMS	28 - 32	5
	Contact	----SRDAMS	27 - 32	6
	IMGT	GFTFSRDA--	23 - 30	8
HFR2	Chothia	AMSWVRQAPGKGLEWVSSI	30 - 48	19
	AbM	---WVRQAPGKGLEWVS--	33 - 46	14
	Kabat	---WVRQAPGKGLEWVS--	33 - 46	14
	Contact	---WVRQAPGKGLE-----	33 - 43	11
	IMGT	-MSWVRQAPGKGLEWVSS-	31 - 47	17
CDR-H2	Chothia	-----VASGRD---------	49 - 54	6
	AbM	---SIVASGRDTR-------	47 - 56	10
	Kabat	---SIVASGRDTRYADSVKG	47 - 63	17
	Contact	WVSSIVASGRDTR-------	44 - 56	13
	IMGT	----IVASGRDT--------	48 - 55	8
HFR3	Chothia	TRYADSVKGRFTISRDNAKNTLYLQMNSLRPEDTAVYYCTK	55 - 95	41
	AbM	--YADSVKGRFTISRDNAKNTLYLQMNSLRPEDTAVYYCTK	57 - 95	39
	Kabat	---------RFTISRDNAKNTLYLQMNSLRPEDTAVYYCTK	64 - 95	32
	Contact	--YADSVKGRFTISRDNAKNTLYLQMNSLRPEDTAVYYC--	57 - 93	37
	IMGT	-RYADSVKGRFTISRDNAKNTLYLQMNSLRPEDTAVYYC--	56 - 93	38
CDR-H3	Chothia	--TPKSDTDWST	96 - 105	10
	AbM	--TPKSDTDWST	96 - 105	10
	Kabat	--TPKSDTDWST	96 - 105	10
	Contact	TKTPKSDTDWS-	94 - 104	11
	IMGT	TKTPKSDTDWST	94 - 105	12
HFR4	Chothia	-PGQGTQVI	106 - 113	8
	AbM	-PGQGTQVI	106 - 113	8
	Kabat	-PGQGTQVI	106 - 113	8
	Contact	TPGQGTQVI	105 - 113	9
	IMGT	-PGQGTQVI	106 - 113	8

Accession & Annotations

Accession	CAJ55310.1
Source	abYsis-EMBL-IG AM180320 Submitted 20-DEC-2005 Updated 27-FEB-2007
Name	immunoglobulin heavy chain variable region
Clone	M205
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Harmsen M.M. Submitted (16-DEC-2005) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., van Solt C.B., Fijten H.P.D., van Keulen L., Rosalia R.A., Weerdmeester K., Cornelissen .A.H.M., De Bruin M.G.M., Eble P.L., Dekker A. 'Passive immunization of guinea pigs with llama single-domain antibody fragments against foot-and-mouth disease' Vet. Microbiol. 120(3-4):193-206(2007).

Tools

Sequences

Amino Acid Sequence:

LQQSGGGLVQPGGSLRLSCAASGFTFSRDAMSWVRQAPGKGLEWVSSIVASGRDTRYADS
VKGRFTISRDNAKNTLYLQMNSLRPEDTAVYYCTKTPKSDTDWSTPGQGTQVI

DNA Sequence:

ctgcagcagtcagggggaggcttggtgcagcctggggggtctctgagactctcctgtgca
gcctctggattcaccttcagcagggatgccatgagctgggtccgccaggctccaggaaag
gggctcgagtgggtctcaagtattgttgccagtggtcgtgacacaaggtatgcagactcc
gtgaagggccgattcaccatctccagagacaacgccaagaacacactgtatctacagatg
aacagcctgagacctgaggacacggccgtgtattactgtacaaaaaccccgaagagtgat
actgactggtccaccccaggccaggggacccaggtcatc

Data Source:

Alignment settings:

Search settings: