abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	EVQLEESGGGLVQPGGSLTLSCAASGYTFT	1 - 30	30
CDR-H1	NCAAG	31 - 35	5
HFR2	WYRQAPGKECELVA	36 - 49	14
CDR-H2	SIFSGNRTNYADSVKG	50 - 65	16
HFR3	RFTIARDNTKDIVYLQMNSLKPEDTTVYYCDA	66 - 97	32
CDR-H3	RTPCSPRGPRSTVSS	98 - 112	15
HFR4		-	-
			112

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	EVQLEESGGGLVQPGGSLTLSCAAS-----	1 - 25	25
	AbM	EVQLEESGGGLVQPGGSLTLSCAAS-----	1 - 25	25
	Kabat	EVQLEESGGGLVQPGGSLTLSCAASGYTFT	1 - 30	30
	Contact	EVQLEESGGGLVQPGGSLTLSCAASGYTF-	1 - 29	29
	IMGT	EVQLEESGGGLVQPGGSLTLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GYTFTNC---	26 - 32	7
	AbM	GYTFTNCAAG	26 - 35	10
	Kabat	-----NCAAG	31 - 35	5
	Contact	----TNCAAG	30 - 35	6
	IMGT	GYTFTNCA--	26 - 33	8
HFR2	Chothia	AAGWYRQAPGKECELVASI	33 - 51	19
	AbM	---WYRQAPGKECELVA--	36 - 49	14
	Kabat	---WYRQAPGKECELVA--	36 - 49	14
	Contact	---WYRQAPGKECE-----	36 - 46	11
	IMGT	-AGWYRQAPGKECELVAS-	34 - 50	17
CDR-H2	Chothia	-----FSGNR---------	52 - 56	5
	AbM	---SIFSGNRTN-------	50 - 58	9
	Kabat	---SIFSGNRTNYADSVKG	50 - 65	16
	Contact	LVASIFSGNRTN-------	47 - 58	12
	IMGT	----IFSGNRT--------	51 - 57	7
HFR3	Chothia	TNYADSVKGRFTIARDNTKDIVYLQMNSLKPEDTTVYYCDA	57 - 97	41
	AbM	--YADSVKGRFTIARDNTKDIVYLQMNSLKPEDTTVYYCDA	59 - 97	39
	Kabat	---------RFTIARDNTKDIVYLQMNSLKPEDTTVYYCDA	66 - 97	32
	Contact	--YADSVKGRFTIARDNTKDIVYLQMNSLKPEDTTVYYC--	59 - 95	37
	IMGT	-NYADSVKGRFTIARDNTKDIVYLQMNSLKPEDTTVYYC--	58 - 95	38
CDR-H3	Chothia	--RTPCSPRGPRSTVSS	98 - 112	15
	AbM	--RTPCSPRGPRSTVSS	98 - 112	15
	Kabat	--RTPCSPRGPRSTVSS	98 - 112	15
	Contact	DARTPCSPRGPRSTVSS	96 - 112	17
	IMGT	DARTPCSPRGPRSTVSS	96 - 112	17
HFR4	Chothia		-	-
	AbM		-	-
	Kabat		-	-
	Contact		-	-
	IMGT		-	-

Accession & Annotations

Accession	ACA42552.1
Source	abYsis-EMBL-IG EU450798 Submitted 04-MAR-2008 Updated 04-MAR-2008
Name	immunoglobulin heavy chain variable region
Clone	AR1-86
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Ahmadvand D., Rasaee M.J. Submitted (08-FEB-2008) to the INSDC. Clinical Biochemistry, Tarbiat Modares University, Jalale-ale-Ahmad, Tehran 14115331, Iran Ahmadvand D., Rasaee M.J. 'Production and Characterization of a High Affinity Nanobody Against Human Endoglin (CD105)' Unpublished.

Tools

Sequences

Amino Acid Sequence:

EVQLEESGGGLVQPGGSLTLSCAASGYTFTNCAAGWYRQAPGKECELVASIFSGNRTNYA
DSVKGRFTIARDNTKDIVYLQMNSLKPEDTTVYYCDARTPCSPRGPRSTVSS

DNA Sequence:

gaggtgcagctggaggagtccgggggaggcttggtgcagcctggggggtctctgacactc
tcctgtgcagcgtctggatacaccttcactaactgtgccgcgggctggtaccgccaggct
ccaggaaaggagtgcgaattggtcgcaagtatttttagtgggaataggacaaactatgcc
gactccgtgaagggccgatttaccatcgcccgagacaacaccaaggatattgtgtatctg
caaatgaacagcctgaaaccagaggacacgaccgtctattactgcgacgcgcgtactcca
tgtagtccaaggggacccaggtcgaccgtctcctca

Data Source:

Alignment settings:

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