abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLEESGGGLVQAGGSLRLSCAASGRTSS	1 - 30	30
CDR-H1	NTFVG	31 - 35	5
HFR2	WFRQAPGKEREFVA	36 - 49	14
CDR-H2	AIRRSDDRTYYAASVRG	50 - 66	17
HFR3	RFTISGDSAKNVVALQMSSLRPEDTAVYYCAA	67 - 98	32
CDR-H3	TRTWLVTGQSDYPY	99 - 112	14
HFR4	WGQGTQVTVSS	113 - 123	11
			123

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLEESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLEESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLEESGGGLVQAGGSLRLSCAASGRTSS	1 - 30	30
	Contact	QVQLEESGGGLVQAGGSLRLSCAASGRTS-	1 - 29	29
	IMGT	QVQLEESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GRTSSNT---	26 - 32	7
	AbM	GRTSSNTFVG	26 - 35	10
	Kabat	-----NTFVG	31 - 35	5
	Contact	----SNTFVG	30 - 35	6
	IMGT	GRTSSNTF--	26 - 33	8
HFR2	Chothia	FVGWFRQAPGKEREFVAAI	33 - 51	19
	AbM	---WFRQAPGKEREFVA--	36 - 49	14
	Kabat	---WFRQAPGKEREFVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-VGWFRQAPGKEREFVAA-	34 - 50	17
CDR-H2	Chothia	-----RRSDDR---------	52 - 57	6
	AbM	---AIRRSDDRTY-------	50 - 59	10
	Kabat	---AIRRSDDRTYYAASVRG	50 - 66	17
	Contact	FVAAIRRSDDRTY-------	47 - 59	13
	IMGT	----IRRSDDRT--------	51 - 58	8
HFR3	Chothia	TYYAASVRGRFTISGDSAKNVVALQMSSLRPEDTAVYYCAA	58 - 98	41
	AbM	--YAASVRGRFTISGDSAKNVVALQMSSLRPEDTAVYYCAA	60 - 98	39
	Kabat	---------RFTISGDSAKNVVALQMSSLRPEDTAVYYCAA	67 - 98	32
	Contact	--YAASVRGRFTISGDSAKNVVALQMSSLRPEDTAVYYC--	60 - 96	37
	IMGT	-YYAASVRGRFTISGDSAKNVVALQMSSLRPEDTAVYYC--	59 - 96	38
CDR-H3	Chothia	--TRTWLVTGQSDYPY	99 - 112	14
	AbM	--TRTWLVTGQSDYPY	99 - 112	14
	Kabat	--TRTWLVTGQSDYPY	99 - 112	14
	Contact	AATRTWLVTGQSDYP-	97 - 111	15
	IMGT	AATRTWLVTGQSDYPY	97 - 112	16
HFR4	Chothia	-WGQGTQVTVSS	113 - 123	11
	AbM	-WGQGTQVTVSS	113 - 123	11
	Kabat	-WGQGTQVTVSS	113 - 123	11
	Contact	YWGQGTQVTVSS	112 - 123	12
	IMGT	-WGQGTQVTVSS	113 - 123	11

Accession & Annotations

Accession	ACD81985.1
Source	abYsis-EMBL-IG EU676170 Submitted 04-JUN-2008 Updated 08-OCT-2008
Name	anti-15-acetyl-deoxynivalenol immunoglobulin heavy chain variable region
Clone	VhhNAT267
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Doyle P.J., Arbabi-Ghahroudi M., Gaudette N., Furzer G., Savard M.E., Gleddie S., McLean M.D., Mackenzie C.R., Hall J.C. 'Cloning, expression, and characterization of a single-domain antibody fragment with affinity for 15-acetyl-deoxynivalenol' Mol. Immunol. 45(14):3703-3713(2008). Doyle P., Arbabi-Ghahroudi M., Gaudette N., Furzer G., Savard M.E., Gleddie S., McLean M.D., MacKenzie C.R., Hall J.C. Submitted (24-APR-2008) to the INSDC. Environmental Biology, University of Guelph, 50 Stone Rd. E., Guelph, ON N1G 2W1, Canada

Tools

Sequences

Amino Acid Sequence:

QVQLEESGGGLVQAGGSLRLSCAASGRTSSNTFVGWFRQAPGKEREFVAAIRRSDDRTYY
AASVRGRFTISGDSAKNVVALQMSSLRPEDTAVYYCAATRTWLVTGQSDYPYWGQGTQVT
VSS

DNA Sequence:

caggtacagctggaggagtctgggggaggattggtgcaggctgggggctctctgagactc
tcctgtgcagcctctggacgcacctccagtaacacgtttgtgggctggttccgccaggct
ccggggaaggagcgtgagtttgtagcagctattaggcggagtgatgatcgcacatactat
gcagcctccgtgaggggccgattcaccatctccggagacagcgccaagaacgtggtggct
ctgcaaatgagcagcctgagacctgaggacacggccgtttattactgcgcagcaaccagg
acgtggttagtaactggccaatctgactatccctactggggccaggggacccaggtcacc
gtctcctca

Data Source:

Alignment settings:

Search settings: