abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVQLQESGGGSVQAGGSLKLSCAISGYDND	1 - 30	30
CDR-H1	NYCMG	31 - 35	5
HFR2	WFRQTPGKEREKVA	36 - 49	14
CDR-H2	ALNIGGGSPVYADFVRG	50 - 66	17
HFR3	RFTISLDSSKDTLYLLMNAVTPEDTAMYYCAA	67 - 98	32
CDR-H3	IRKPQFYTCRMWKPRADFDI	99 - 118	20
HFR4	WGQGTQVTVSS	119 - 129	11
			129

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLQESGGGSVQAGGSLKLSCAIS-----	1 - 25	25
	AbM	DVQLQESGGGSVQAGGSLKLSCAIS-----	1 - 25	25
	Kabat	DVQLQESGGGSVQAGGSLKLSCAISGYDND	1 - 30	30
	Contact	DVQLQESGGGSVQAGGSLKLSCAISGYDN-	1 - 29	29
	IMGT	DVQLQESGGGSVQAGGSLKLSCAIS-----	1 - 25	25
CDR-H1	Chothia	GYDNDNY---	26 - 32	7
	AbM	GYDNDNYCMG	26 - 35	10
	Kabat	-----NYCMG	31 - 35	5
	Contact	----DNYCMG	30 - 35	6
	IMGT	GYDNDNYC--	26 - 33	8
HFR2	Chothia	CMGWFRQTPGKEREKVAAL	33 - 51	19
	AbM	---WFRQTPGKEREKVA--	36 - 49	14
	Kabat	---WFRQTPGKEREKVA--	36 - 49	14
	Contact	---WFRQTPGKERE-----	36 - 46	11
	IMGT	-MGWFRQTPGKEREKVAA-	34 - 50	17
CDR-H2	Chothia	-----NIGGGS---------	52 - 57	6
	AbM	---ALNIGGGSPV-------	50 - 59	10
	Kabat	---ALNIGGGSPVYADFVRG	50 - 66	17
	Contact	KVAALNIGGGSPV-------	47 - 59	13
	IMGT	----LNIGGGSP--------	51 - 58	8
HFR3	Chothia	PVYADFVRGRFTISLDSSKDTLYLLMNAVTPEDTAMYYCAA	58 - 98	41
	AbM	--YADFVRGRFTISLDSSKDTLYLLMNAVTPEDTAMYYCAA	60 - 98	39
	Kabat	---------RFTISLDSSKDTLYLLMNAVTPEDTAMYYCAA	67 - 98	32
	Contact	--YADFVRGRFTISLDSSKDTLYLLMNAVTPEDTAMYYC--	60 - 96	37
	IMGT	-VYADFVRGRFTISLDSSKDTLYLLMNAVTPEDTAMYYC--	59 - 96	38
CDR-H3	Chothia	--IRKPQFYTCRMWKPRADFDI	99 - 118	20
	AbM	--IRKPQFYTCRMWKPRADFDI	99 - 118	20
	Kabat	--IRKPQFYTCRMWKPRADFDI	99 - 118	20
	Contact	AAIRKPQFYTCRMWKPRADFD-	97 - 117	21
	IMGT	AAIRKPQFYTCRMWKPRADFDI	97 - 118	22
HFR4	Chothia	-WGQGTQVTVSS	119 - 129	11
	AbM	-WGQGTQVTVSS	119 - 129	11
	Kabat	-WGQGTQVTVSS	119 - 129	11
	Contact	IWGQGTQVTVSS	118 - 129	12
	IMGT	-WGQGTQVTVSS	119 - 129	11

Accession & Annotations

Accession	ACF49483.1
Source	abYsis-EMBL-IG EU861212 Submitted 26-JUL-2008 Updated 26-JUL-2008
Name	anti-LPS immunoglobulin heavy chain variable region
Clone	28-16
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Singh A., Pandey N. Submitted (30-JUN-2008) to the INSDC. Immunology Section, Department of Veterinary Microbiology, Ch. Charan Singh Haryana Agricultural University, College of Veterinary Sciences, Hisar, Haryana 125004, India Singh A., Pandey N. 'Nucleotide sequence of anti-Escherichia coli O153 lipopolysaccharide VHH cDNA clone of Indian desert camel (Camelus dromedarius)' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DVQLQESGGGSVQAGGSLKLSCAISGYDNDNYCMGWFRQTPGKEREKVAALNIGGGSPVY
ADFVRGRFTISLDSSKDTLYLLMNAVTPEDTAMYYCAAIRKPQFYTCRMWKPRADFDIWG
QGTQVTVSS

DNA Sequence:

gatgtgcagctgcaggagtctggaggaggctcggtgcaggctggaggctctctgaaactc
tcctgtgcaatttctggatacgacaacgataactactgcatgggctggttccgccaaacg
ccagggaaggagcgtgagaaagtcgcggcccttaatattggaggtggtagcccagtctac
gccgatttcgtgaggggccgattcaccatctccctggactccagcaaggacacactgtac
ctcctgatgaacgcagtgacacccgaggacacggccatgtattactgtgcggcaatccgt
aagccccaattctatacttgccgtatgtggaaaccaagagctgactttgatatctggggc
caggggacccaggtcaccgtctccagc

Data Source:

Alignment settings:

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