abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	GGGLVQAGGSLRLSCVASGRTFS	1 - 23	23
CDR-H1	SYIMA	24 - 28	5
HFR2	WFRQAPGKEREFVA	29 - 42	14
CDR-H2	ASSWGGDTYYADSVKG	43 - 58	16
HFR3	RFTVSRHNAKNTVYLQMNSLKPEDAAVYYCAE	59 - 90	32
CDR-H3	NDNYCSGYGCYDYMGYDY	91 - 108	18
HFR4	WGPG	109 - 112	4
			112

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	GGGLVQAGGSLRLSCVAS-----	1 - 18	18
	AbM	GGGLVQAGGSLRLSCVAS-----	1 - 18	18
	Kabat	GGGLVQAGGSLRLSCVASGRTFS	1 - 23	23
	Contact	GGGLVQAGGSLRLSCVASGRTF-	1 - 22	22
	IMGT	GGGLVQAGGSLRLSCVAS-----	1 - 18	18
CDR-H1	Chothia	GRTFSSY---	19 - 25	7
	AbM	GRTFSSYIMA	19 - 28	10
	Kabat	-----SYIMA	24 - 28	5
	Contact	----SSYIMA	23 - 28	6
	IMGT	GRTFSSYI--	19 - 26	8
HFR2	Chothia	IMAWFRQAPGKEREFVAAS	26 - 44	19
	AbM	---WFRQAPGKEREFVA--	29 - 42	14
	Kabat	---WFRQAPGKEREFVA--	29 - 42	14
	Contact	---WFRQAPGKERE-----	29 - 39	11
	IMGT	-MAWFRQAPGKEREFVAA-	27 - 43	17
CDR-H2	Chothia	-----SWGGD---------	45 - 49	5
	AbM	---ASSWGGDTY-------	43 - 51	9
	Kabat	---ASSWGGDTYYADSVKG	43 - 58	16
	Contact	FVAASSWGGDTY-------	40 - 51	12
	IMGT	----SSWGGDT--------	44 - 50	7
HFR3	Chothia	TYYADSVKGRFTVSRHNAKNTVYLQMNSLKPEDAAVYYCAE	50 - 90	41
	AbM	--YADSVKGRFTVSRHNAKNTVYLQMNSLKPEDAAVYYCAE	52 - 90	39
	Kabat	---------RFTVSRHNAKNTVYLQMNSLKPEDAAVYYCAE	59 - 90	32
	Contact	--YADSVKGRFTVSRHNAKNTVYLQMNSLKPEDAAVYYC--	52 - 88	37
	IMGT	-YYADSVKGRFTVSRHNAKNTVYLQMNSLKPEDAAVYYC--	51 - 88	38
CDR-H3	Chothia	--NDNYCSGYGCYDYMGYDY	91 - 108	18
	AbM	--NDNYCSGYGCYDYMGYDY	91 - 108	18
	Kabat	--NDNYCSGYGCYDYMGYDY	91 - 108	18
	Contact	AENDNYCSGYGCYDYMGYD-	89 - 107	19
	IMGT	AENDNYCSGYGCYDYMGYDY	89 - 108	20
HFR4	Chothia	-WGPG	109 - 112	4
	AbM	-WGPG	109 - 112	4
	Kabat	-WGPG	109 - 112	4
	Contact	YWGPG	108 - 112	5
	IMGT	-WGPG	109 - 112	4

Accession & Annotations

Accession	ACJ09035.1
Source	abYsis-EMBL-IG FJ155929 Submitted 05-NOV-2008 Updated 21-APR-2010
Name	anti-gliadin single domain antibody
Clone	26
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Urrutia M., Dona V., Goldbaum F.A., Chirdo F.G. Submitted (22-AUG-2008) to the INSDC. Fundacion Instituto Leloir, Av. Patricias Argentinas 435, Buenos Aires C1405BWE, Argentina Dona V., Urrutia M., Bayardo M., Alzogaray V., Goldbaum F.A., Chirdo F.G. 'Single domain antibodies are specially suited for quantitative determination of gliadins under denaturing conditions' J. Agric. Food Chem. 58(2):918-926(2010).

Tools

Sequences

Amino Acid Sequence:

GGGLVQAGGSLRLSCVASGRTFSSYIMAWFRQAPGKEREFVAASSWGGDTYYADSVKGRF
TVSRHNAKNTVYLQMNSLKPEDAAVYYCAENDNYCSGYGCYDYMGYDYWGPG

DNA Sequence:

gggggaggattggtgcaggctgggggctctctgagactctcctgtgtagcctctggacgc
accttcagttcctatatcatggcctggttccgccaggctccagggaaggagcgtgagttt
gtagcagcttctagctggggtggtgacacatactatgcagactccgtgaagggccgattc
accgtctccagacacaacgccaagaacacagtgtatctgcaaatgaacagcctgaaacct
gaggacgcggccgtttattactgtgcagagaacgataactactgctcaggctatgggtgt
tatgattatatggggtatgactactggggcccgggg

Data Source:

Alignment settings:

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