abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLRLSCAASGLTDS	1 - 30	30
CDR-H1	TCGMA	31 - 35	5
HFR2	WYRQAPGKERELVS	36 - 49	14
CDR-H2	TIITDGNTYYADSVKG	50 - 65	16
HFR3	RFTISQDNAKNRVFLQMNSLKPEDTAMYYCNS	66 - 97	32
CDR-H3	WSESKRLCLPDNY	98 - 110	13
HFR4	WGQGTQVTVSS	111 - 121	11
			121

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLRLSCAASGLTDS	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLRLSCAASGLTD-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GLTDSTC---	26 - 32	7
	AbM	GLTDSTCGMA	26 - 35	10
	Kabat	-----TCGMA	31 - 35	5
	Contact	----STCGMA	30 - 35	6
	IMGT	GLTDSTCG--	26 - 33	8
HFR2	Chothia	GMAWYRQAPGKERELVSTI	33 - 51	19
	AbM	---WYRQAPGKERELVS--	36 - 49	14
	Kabat	---WYRQAPGKERELVS--	36 - 49	14
	Contact	---WYRQAPGKERE-----	36 - 46	11
	IMGT	-MAWYRQAPGKERELVST-	34 - 50	17
CDR-H2	Chothia	-----ITDGN---------	52 - 56	5
	AbM	---TIITDGNTY-------	50 - 58	9
	Kabat	---TIITDGNTYYADSVKG	50 - 65	16
	Contact	LVSTIITDGNTY-------	47 - 58	12
	IMGT	----IITDGNT--------	51 - 57	7
HFR3	Chothia	TYYADSVKGRFTISQDNAKNRVFLQMNSLKPEDTAMYYCNS	57 - 97	41
	AbM	--YADSVKGRFTISQDNAKNRVFLQMNSLKPEDTAMYYCNS	59 - 97	39
	Kabat	---------RFTISQDNAKNRVFLQMNSLKPEDTAMYYCNS	66 - 97	32
	Contact	--YADSVKGRFTISQDNAKNRVFLQMNSLKPEDTAMYYC--	59 - 95	37
	IMGT	-YYADSVKGRFTISQDNAKNRVFLQMNSLKPEDTAMYYC--	58 - 95	38
CDR-H3	Chothia	--WSESKRLCLPDNY	98 - 110	13
	AbM	--WSESKRLCLPDNY	98 - 110	13
	Kabat	--WSESKRLCLPDNY	98 - 110	13
	Contact	NSWSESKRLCLPDN-	96 - 109	14
	IMGT	NSWSESKRLCLPDNY	96 - 110	15
HFR4	Chothia	-WGQGTQVTVSS	111 - 121	11
	AbM	-WGQGTQVTVSS	111 - 121	11
	Kabat	-WGQGTQVTVSS	111 - 121	11
	Contact	YWGQGTQVTVSS	110 - 121	12
	IMGT	-WGQGTQVTVSS	111 - 121	11

Accession & Annotations

Accession	AEA07719.1
Source	abYsis-EMBL-IG JF313902 Submitted 30-MAR-2011 Updated 03-MAY-2012
Name	immunoglobulin heavy chain variable region
Clone	NbBruc02
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Abbady A.Q. Submitted (10-FEB-2011) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus, Damascus 6091, Syria Abbady A.Q., Al-Daoude A., Al-Mariri A., Zarkawi M., Muyldermans S. 'Chaperonin GroEL a Brucella immunodominant antigen identified using Nanobody and MALDI-TOF-MS technologies' Vet. Immunol. Immunopathol. 146(3-4):254-263(2012).

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLRLSCAASGLTDSTCGMAWYRQAPGKERELVSTIITDGNTYYA
DSVKGRFTISQDNAKNRVFLQMNSLKPEDTAMYYCNSWSESKRLCLPDNYWGQGTQVTVS
S

DNA Sequence:

caggtgcagctgcaggagtctggaggaggctcggtgcaggctggagggtctctgagactc
tcctgtgcagcctctggattgaccgatagcacctgcggcatggcctggtaccgccaggct
ccagggaaggagcgcgagttggtctcaactattattaccgatggtaacacatactatgca
gattctgtgaagggccgattcaccatctcccaagacaacgccaagaaccgggtgtttctg
caaatgaacagcctgaaacctgaggacacggccatgtattactgtaacagttggtctgag
tcgaagcgactatgtctcccagataactactggggccaggggacccaggtcaccgtctcc
agc

Data Source:

Alignment settings:

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