abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVLPGGSLRLSCATSGFTFS	1 - 30	30
CDR-H1	NSWMY	31 - 35	5
HFR2	WVRQAPGKGLEWVS	36 - 49	14
CDR-H2	RINAGGNTVDYKDSVKG	50 - 66	17
HFR3	RFSISRDNAKNTLYLQMNSLKPEDTAVYYCAR	67 - 98	32
CDR-H3	GLNRYAYDS	99 - 107	9
HFR4	RGQGTQVTVSS	108 - 118	11
Tail	HHHHHHEPEA	118 - 128	10
			128

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVLPGGSLRLSCATS-----	1 - 25	25
	AbM	QVQLQESGGGLVLPGGSLRLSCATS-----	1 - 25	25
	Kabat	QVQLQESGGGLVLPGGSLRLSCATSGFTFS	1 - 30	30
	Contact	QVQLQESGGGLVLPGGSLRLSCATSGFTF-	1 - 29	29
	IMGT	QVQLQESGGGLVLPGGSLRLSCATS-----	1 - 25	25
CDR-H1	Chothia	GFTFSNS---	26 - 32	7
	AbM	GFTFSNSWMY	26 - 35	10
	Kabat	-----NSWMY	31 - 35	5
	Contact	----SNSWMY	30 - 35	6
	IMGT	GFTFSNSW--	26 - 33	8
HFR2	Chothia	WMYWVRQAPGKGLEWVSRI	33 - 51	19
	AbM	---WVRQAPGKGLEWVS--	36 - 49	14
	Kabat	---WVRQAPGKGLEWVS--	36 - 49	14
	Contact	---WVRQAPGKGLE-----	36 - 46	11
	IMGT	-MYWVRQAPGKGLEWVSR-	34 - 50	17
CDR-H2	Chothia	-----NAGGNT---------	52 - 57	6
	AbM	---RINAGGNTVD-------	50 - 59	10
	Kabat	---RINAGGNTVDYKDSVKG	50 - 66	17
	Contact	WVSRINAGGNTVD-------	47 - 59	13
	IMGT	----INAGGNTV--------	51 - 58	8
HFR3	Chothia	VDYKDSVKGRFSISRDNAKNTLYLQMNSLKPEDTAVYYCAR	58 - 98	41
	AbM	--YKDSVKGRFSISRDNAKNTLYLQMNSLKPEDTAVYYCAR	60 - 98	39
	Kabat	---------RFSISRDNAKNTLYLQMNSLKPEDTAVYYCAR	67 - 98	32
	Contact	--YKDSVKGRFSISRDNAKNTLYLQMNSLKPEDTAVYYC--	60 - 96	37
	IMGT	-DYKDSVKGRFSISRDNAKNTLYLQMNSLKPEDTAVYYC--	59 - 96	38
CDR-H3	Chothia	--GLNRYAYDS	99 - 107	9
	AbM	--GLNRYAYDS	99 - 107	9
	Kabat	--GLNRYAYDS	99 - 107	9
	Contact	ARGLNRYAYD-	97 - 106	10
	IMGT	ARGLNRYAYDS	97 - 107	11
HFR4	Chothia	-RGQGTQVTVSS	108 - 118	11
	AbM	-RGQGTQVTVSS	108 - 118	11
	Kabat	-RGQGTQVTVSS	108 - 118	11
	Contact	SRGQGTQVTVSS	107 - 118	12
	IMGT	-RGQGTQVTVSS	108 - 118	11

Accession & Annotations

Accession	5usf_C
Source	PDB 5usf Submitted 13-FEB-2017 Updated 20-SEP-2017
Name	LEISHMANIA DONOVANI TYROSYL-TRNA SYNTHETASE IN COMPLEX WITH NANOBODY AND INHIBITOR
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5usf_D
References	BARROS-ALVAREZ X., KERCHNER M., KOH Y., TURLEY S., PARDON E., STEYAERT J., RANADE M., GILLESPIE R., ZHANG Z., VERLINDE J., FAN E., BUCKNER S., HOL J. 'LEISHMANIA DONOVANI TYROSYL-TRNA SYNTHETASE STRUCTURE IN COMPLEX WITH A TYROSYL ADENYLATE ANALOG AND COMPARISONS WITH HUMAN AND PROTOZOAN COUNTERPARTS.' BIOCHIMIE V. 138 124 2017 ISSN 1638-6183

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVLPGGSLRLSCATSGFTFSNSWMYWVRQAPGKGLEWVSRINAGGNTVDY
KDSVKGRFSISRDNAKNTLYLQMNSLKPEDTAVYYCARGLNRYAYDSRGQGTQVTVSSHH
HHHHEPEA