abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	EVQLEESGGGSVQAGGSLRLSCAASGYTFL	1 - 30	30
CDR-H1	QLLHG	31 - 35	5
HFR2	WFRQAPGKEREVVA	36 - 49	14
CDR-H2	RFNTDINKTFYLESVKG	50 - 66	17
HFR3	RFTLSQDNAKNTLYLQMNSLKPEDTAIYYCAA	67 - 98	32
CDR-H3	SRPDSTCDYFAY	99 - 110	12
HFR4	RGQGTQVTVSS	111 - 121	11
Tail	G	121 - 122	1
			122

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	EVQLEESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	EVQLEESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	EVQLEESGGGSVQAGGSLRLSCAASGYTFL	1 - 30	30
	Contact	EVQLEESGGGSVQAGGSLRLSCAASGYTF-	1 - 29	29
	IMGT	EVQLEESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GYTFLQL---	26 - 32	7
	AbM	GYTFLQLLHG	26 - 35	10
	Kabat	-----QLLHG	31 - 35	5
	Contact	----LQLLHG	30 - 35	6
	IMGT	GYTFLQLL--	26 - 33	8
HFR2	Chothia	LHGWFRQAPGKEREVVARF	33 - 51	19
	AbM	---WFRQAPGKEREVVA--	36 - 49	14
	Kabat	---WFRQAPGKEREVVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-HGWFRQAPGKEREVVAR-	34 - 50	17
CDR-H2	Chothia	-----NTDINK---------	52 - 57	6
	AbM	---RFNTDINKTF-------	50 - 59	10
	Kabat	---RFNTDINKTFYLESVKG	50 - 66	17
	Contact	VVARFNTDINKTF-------	47 - 59	13
	IMGT	----FNTDINKT--------	51 - 58	8
HFR3	Chothia	TFYLESVKGRFTLSQDNAKNTLYLQMNSLKPEDTAIYYCAA	58 - 98	41
	AbM	--YLESVKGRFTLSQDNAKNTLYLQMNSLKPEDTAIYYCAA	60 - 98	39
	Kabat	---------RFTLSQDNAKNTLYLQMNSLKPEDTAIYYCAA	67 - 98	32
	Contact	--YLESVKGRFTLSQDNAKNTLYLQMNSLKPEDTAIYYC--	60 - 96	37
	IMGT	-FYLESVKGRFTLSQDNAKNTLYLQMNSLKPEDTAIYYC--	59 - 96	38
CDR-H3	Chothia	--SRPDSTCDYFAY	99 - 110	12
	AbM	--SRPDSTCDYFAY	99 - 110	12
	Kabat	--SRPDSTCDYFAY	99 - 110	12
	Contact	AASRPDSTCDYFA-	97 - 109	13
	IMGT	AASRPDSTCDYFAY	97 - 110	14
HFR4	Chothia	-RGQGTQVTVSS	111 - 121	11
	AbM	-RGQGTQVTVSS	111 - 121	11
	Kabat	-RGQGTQVTVSS	111 - 121	11
	Contact	YRGQGTQVTVSS	110 - 121	12
	IMGT	-RGQGTQVTVSS	111 - 121	11

Accession & Annotations

Accession	AFW03624.1
Source	abYsis-EMBL-IG JX576803 Submitted 13-NOV-2012 Updated 10-MAY-2014
Name	immunoglobin heavy chain variable region
Clone	NbRR16
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Rahimi Jamnani F., Rahbarizadeh F., Shokrgozar M.A., Mahboudi F. Submitted (04-SEP-2012) to the INSDC. Biotechnology Research Center, Pasteur Institute, 12 Farvardin, Tehran 13164, Iran Jamnani F.R., Rahbarizadeh F., Shokrgozar M.A., Mahboudi F., Ahmadvand D., Sharifzadeh Z., Parhamifar L., Moghimi S.M. 'T cells expressing VHH-directed oligoclonal chimeric HER2 antigen receptors: towards tumor-directed oligoclonal T cell therapy' Biochim. Biophys. Acta 1840(1):378-386(2014).

Tools

Sequences

Amino Acid Sequence:

EVQLEESGGGSVQAGGSLRLSCAASGYTFLQLLHGWFRQAPGKEREVVARFNTDINKTFY
LESVKGRFTLSQDNAKNTLYLQMNSLKPEDTAIYYCAASRPDSTCDYFAYRGQGTQVTVS
SG

DNA Sequence:

gaggtgcagctggaggagtctgggggaggctcggtgcaggctggagggtcgctgagactc
tcctgtgcagcctctggatacacctttctccagctcctgcatggctggttccgccaggct
ccagggaaggagcgtgaggtcgtcgcacgttttaatacggatattaataaaacattctat
ctcgagtccgtgaagggccgattcaccctctcccaagacaatgccaagaacacgctgtat
ctgcagatgaacagtctgaaaccggaggacacggccatctattactgtgcggcatctcgg
ccggactctacctgcgattattttgcctacaggggccaggggacccaggtcaccgtgtcc
tcaggc

Data Source:

Alignment settings:

Search settings: