abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	A	1 - 1	1
HFR1	GLVGGLKARSLVQAGGSLRLACAASASGYT	2 - 31	30
CDR-H1	ESVKWMG	32 - 38	7
HFR2	WFRQAPGQEREGVA	39 - 52	14
CDR-H2	VISIPGGSTYYDDHVKG	53 - 69	17
HFR3	RFTISQDNAQNTVYLQMNSLKPEDTAMYYCAA	70 - 101	32
CDR-H3	RNAGGRFRPSAAGGYNY	102 - 118	17
HFR4	WGQGTQVTVSS	119 - 129	11
Tail	GQPRPIKK	129 - 137	8
			137

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	GLVGGLKARSLVQAGGSLRLACAAS-----	2 - 26	25
	AbM	GLVGGLKARSLVQAGGSLRLACAAS-----	2 - 26	25
	Kabat	GLVGGLKARSLVQAGGSLRLACAASASGYT	2 - 31	30
	Contact	GLVGGLKARSLVQAGGSLRLACAASASGY-	2 - 30	29
	IMGT	GLVGGLKARSLVQAGGSLRLACAAS-----	2 - 26	25
CDR-H1	Chothia	ASGYTESVK---	27 - 35	9
	AbM	ASGYTESVKWMG	27 - 38	12
	Kabat	-----ESVKWMG	32 - 38	7
	Contact	----TESVKWMG	31 - 38	8
	IMGT	ASGYTESVKW--	27 - 36	10
HFR2	Chothia	WMGWFRQAPGQEREGVAVI	36 - 54	19
	AbM	---WFRQAPGQEREGVA--	39 - 52	14
	Kabat	---WFRQAPGQEREGVA--	39 - 52	14
	Contact	---WFRQAPGQERE-----	39 - 49	11
	IMGT	-MGWFRQAPGQEREGVAV-	37 - 53	17
CDR-H2	Chothia	-----SIPGGS---------	55 - 60	6
	AbM	---VISIPGGSTY-------	53 - 62	10
	Kabat	---VISIPGGSTYYDDHVKG	53 - 69	17
	Contact	GVAVISIPGGSTY-------	50 - 62	13
	IMGT	----ISIPGGST--------	54 - 61	8
HFR3	Chothia	TYYDDHVKGRFTISQDNAQNTVYLQMNSLKPEDTAMYYCAA	61 - 101	41
	AbM	--YDDHVKGRFTISQDNAQNTVYLQMNSLKPEDTAMYYCAA	63 - 101	39
	Kabat	---------RFTISQDNAQNTVYLQMNSLKPEDTAMYYCAA	70 - 101	32
	Contact	--YDDHVKGRFTISQDNAQNTVYLQMNSLKPEDTAMYYC--	63 - 99	37
	IMGT	-YYDDHVKGRFTISQDNAQNTVYLQMNSLKPEDTAMYYC--	62 - 99	38
CDR-H3	Chothia	--RNAGGRFRPSAAGGYNY	102 - 118	17
	AbM	--RNAGGRFRPSAAGGYNY	102 - 118	17
	Kabat	--RNAGGRFRPSAAGGYNY	102 - 118	17
	Contact	AARNAGGRFRPSAAGGYN-	100 - 117	18
	IMGT	AARNAGGRFRPSAAGGYNY	100 - 118	19
HFR4	Chothia	-WGQGTQVTVSS	119 - 129	11
	AbM	-WGQGTQVTVSS	119 - 129	11
	Kabat	-WGQGTQVTVSS	119 - 129	11
	Contact	YWGQGTQVTVSS	118 - 129	12
	IMGT	-WGQGTQVTVSS	119 - 129	11

Accession & Annotations

Accession	AFY09731.1
Source	abYsis-EMBL-IG KC189943 Submitted 04-DEC-2012 Updated 04-DEC-2012
Name	immunoglobulin heavy chain variable region
Clone	CL9P4
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Ebrahimizadeh W., Mousavi Gargari S., Rajabibazl M., Safaee Ardekani L., Zare H., Bakherad H. 'Isolation and characterization of protective anti-LPS nanobody against V. cholerae O1 recognizing Inaba and Ogawa serotypes' Appl Microbiol Biotechnol 0:0-0(2012). Ebrahimizadeh W., Mousavi Gargari S., Rajabibazl M. Submitted (18-NOV-2012) to the INSDC. Biotechnology, Faculty of Basic Science, Shahed University, Tehran-Qom Expressway, Opposite Imam Khomeini's Shrine, Tehran, Tehran 1865133191, Iran

Tools

Sequences

Amino Acid Sequence:

AGLVGGLKARSLVQAGGSLRLACAASASGYTESVKWMGWFRQAPGQEREGVAVISIPGGS
TYYDDHVKGRFTISQDNAQNTVYLQMNSLKPEDTAMYYCAARNAGGRFRPSAAGGYNYWG
QGTQVTVSSGQPRPIKK

DNA Sequence:

ccgcgggcctggtgggtgggttaaaagcgcggagcttagtgcaggctggagggtctctga
gactcgcctgtgcagcctcagcctctggatacaccgaaagtgtgaagtggatgggctggt
tccgccaggctccagggcaggagcgcgagggggtcgcagttatttctattcctggtggta
gtacatactatgacgaccacgtgaagggccgatttaccatctcccaagacaacgcccaga
acacggtgtatctgcaaatgaacagtctgaaacctgaggacactgccatgtactattgcg
cagcgcgcaatgcgggggggcgttttcggccttcggccgctggtgggtataattattggg
gccaggggacccaggtcaccgtctcctcaggccagccccggccaataaaaaaaa

Data Source:

Alignment settings:

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