abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVQLVESGGGLVQAGGSLRLSCTASGFTFD	1 - 30	30
CDR-H1	DCTMG	31 - 35	5
HFR2	WFRQAPGKEREGVS	36 - 49	14
CDR-H2	YIGWSGSTSGSTTYYTDSVKG	50 - 70	21
HFR3	RFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	71 - 102	32
CDR-H3	ARYRGIGSRVRWTDFIY	103 - 119	17
HFR4	WGQGTQVTVS	120 - 129	10
			129

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLVESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
	AbM	DVQLVESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
	Kabat	DVQLVESGGGLVQAGGSLRLSCTASGFTFD	1 - 30	30
	Contact	DVQLVESGGGLVQAGGSLRLSCTASGFTF-	1 - 29	29
	IMGT	DVQLVESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
CDR-H1	Chothia	GFTFDDC---	26 - 32	7
	AbM	GFTFDDCTMG	26 - 35	10
	Kabat	-----DCTMG	31 - 35	5
	Contact	----DDCTMG	30 - 35	6
	IMGT	GFTFDDCT--	26 - 33	8
HFR2	Chothia	TMGWFRQAPGKEREGVSYI	33 - 51	19
	AbM	---WFRQAPGKEREGVS--	36 - 49	14
	Kabat	---WFRQAPGKEREGVS--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVSY-	34 - 50	17
CDR-H2	Chothia	-----GWSGSTSGST---------	52 - 61	10
	AbM	---YIGWSGSTSGSTTY-------	50 - 63	14
	Kabat	---YIGWSGSTSGSTTYYTDSVKG	50 - 70	21
	Contact	GVSYIGWSGSTSGSTTY-------	47 - 63	17
	IMGT	----IGWSGSTSGSTT--------	51 - 62	12
HFR3	Chothia	TYYTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	62 - 102	41
	AbM	--YTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	64 - 102	39
	Kabat	---------RFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	71 - 102	32
	Contact	--YTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYC--	64 - 100	37
	IMGT	-YYTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYC--	63 - 100	38
CDR-H3	Chothia	--ARYRGIGSRVRWTDFIY	103 - 119	17
	AbM	--ARYRGIGSRVRWTDFIY	103 - 119	17
	Kabat	--ARYRGIGSRVRWTDFIY	103 - 119	17
	Contact	AAARYRGIGSRVRWTDFI-	101 - 118	18
	IMGT	AAARYRGIGSRVRWTDFIY	101 - 119	19
HFR4	Chothia	-WGQGTQVTVS	120 - 129	10
	AbM	-WGQGTQVTVS	120 - 129	10
	Kabat	-WGQGTQVTVS	120 - 129	10
	Contact	YWGQGTQVTVS	119 - 129	11
	IMGT	-WGQGTQVTVS	120 - 129	10

Accession & Annotations

Accession	AHW48351.1
Source	abYsis-EMBL-IG KJ158167 Submitted 14-APR-2014 Updated 20-JUN-2014
Name	anti-PCV2 immunoglobulin heavy chain variable region
Clone	VHH-C3
Organism	Camelus bactrianus
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Yang S., Shang Y., Yin S., Tian H., Chen Y., Sun S., Jin Y., Liu X. 'Selection and identification of single-domain antibody fragment against capsid protein of porcine circovirus type 2 (PCV2) from C. bactrianus' Vet. Immunol. Immunopathol. 160(1-2):12-19(2014). Yang S.L., Yin S., Shang Y., Liu X. Submitted (16-JAN-2014) to the INSDC. State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou, Gansu 730046, China

Tools

Sequences

Amino Acid Sequence:

DVQLVESGGGLVQAGGSLRLSCTASGFTFDDCTMGWFRQAPGKEREGVSYIGWSGSTSGS
TTYYTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYCAAARYRGIGSRVRWTDFIYW
GQGTQVTVS

DNA Sequence:

gatgtgcagctggtggagtctgggggaggcttggtgcaggcaggggggtctctgagactc
tcctgtacagcctctggattcacttttgatgattgtaccatgggctggttccgccaggct
ccagggaaggagcgcgagggggtctcatatattggttggagtggtagtacgagtggtagt
accacatactatacggactccgtgaagggccgattcaccatctccagagacaacgccaag
aacacgctgtatttgcaaatgaatagcctgaaacctgaggacacggccatgtattactgt
gcggcagcccgttaccgtgggattgggtcccgagtgcggtggactgactttatttactgg
ggccaggggacccaggtcaccgtctcc

Data Source:

Alignment settings:

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