abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVQLVESGGGLVQAGGSLRLSCTASGFTFD	1 - 30	30
CDR-H1	DYTMG	31 - 35	5
HFR2	WFRQAPGKEREGVS	36 - 49	14
CDR-H2	YTGWSGSMSGSTTYYTDSVKG	50 - 70	21
HFR3	RFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	71 - 102	32
CDR-H3	ARYRGIGSQVRWTDFIY	103 - 119	17
HFR4	WGQGTQVTVS	120 - 129	10
			129

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLVESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
	AbM	DVQLVESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
	Kabat	DVQLVESGGGLVQAGGSLRLSCTASGFTFD	1 - 30	30
	Contact	DVQLVESGGGLVQAGGSLRLSCTASGFTF-	1 - 29	29
	IMGT	DVQLVESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
CDR-H1	Chothia	GFTFDDY---	26 - 32	7
	AbM	GFTFDDYTMG	26 - 35	10
	Kabat	-----DYTMG	31 - 35	5
	Contact	----DDYTMG	30 - 35	6
	IMGT	GFTFDDYT--	26 - 33	8
HFR2	Chothia	TMGWFRQAPGKEREGVSYT	33 - 51	19
	AbM	---WFRQAPGKEREGVS--	36 - 49	14
	Kabat	---WFRQAPGKEREGVS--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVSY-	34 - 50	17
CDR-H2	Chothia	-----GWSGSMSGST---------	52 - 61	10
	AbM	---YTGWSGSMSGSTTY-------	50 - 63	14
	Kabat	---YTGWSGSMSGSTTYYTDSVKG	50 - 70	21
	Contact	GVSYTGWSGSMSGSTTY-------	47 - 63	17
	IMGT	----TGWSGSMSGSTT--------	51 - 62	12
HFR3	Chothia	TYYTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	62 - 102	41
	AbM	--YTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	64 - 102	39
	Kabat	---------RFTISRDNAKNTLYLQMNSLKPEDTAMYYCAA	71 - 102	32
	Contact	--YTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYC--	64 - 100	37
	IMGT	-YYTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYC--	63 - 100	38
CDR-H3	Chothia	--ARYRGIGSQVRWTDFIY	103 - 119	17
	AbM	--ARYRGIGSQVRWTDFIY	103 - 119	17
	Kabat	--ARYRGIGSQVRWTDFIY	103 - 119	17
	Contact	AAARYRGIGSQVRWTDFI-	101 - 118	18
	IMGT	AAARYRGIGSQVRWTDFIY	101 - 119	19
HFR4	Chothia	-WGQGTQVTVS	120 - 129	10
	AbM	-WGQGTQVTVS	120 - 129	10
	Kabat	-WGQGTQVTVS	120 - 129	10
	Contact	YWGQGTQVTVS	119 - 129	11
	IMGT	-WGQGTQVTVS	120 - 129	10

Accession & Annotations

Accession	AHW48352.1
Source	abYsis-EMBL-IG KJ158168 Submitted 14-APR-2014 Updated 20-JUN-2014
Name	anti-PCV2 immunoglobulin heavy chain variable region
Clone	VHH-C1
Organism	Camelus bactrianus
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Yang S., Shang Y., Yin S., Tian H., Chen Y., Sun S., Jin Y., Liu X. 'Selection and identification of single-domain antibody fragment against capsid protein of porcine circovirus type 2 (PCV2) from C. bactrianus' Vet. Immunol. Immunopathol. 160(1-2):12-19(2014). Yang S.L., Yin S., Shang Y., Liu X. Submitted (16-JAN-2014) to the INSDC. State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou, Gansu 730046, China

Tools

Sequences

Amino Acid Sequence:

DVQLVESGGGLVQAGGSLRLSCTASGFTFDDYTMGWFRQAPGKEREGVSYTGWSGSMSGS
TTYYTDSVKGRFTISRDNAKNTLYLQMNSLKPEDTAMYYCAAARYRGIGSQVRWTDFIYW
GQGTQVTVS

DNA Sequence:

gatgtgcagctggtggagtctgggggaggcttggtgcaggcaggggggtctctgagactc
tcctgtacagcctctggattcacttttgatgattataccatgggctggttccgccaggct
ccagggaaggagcgcgagggggtctcatatacaggttggagtggtagtatgagtggtagt
accacatactatacggactccgtgaagggccgattcaccatctccagagacaacgccaag
aacacgctgtatctgcaaatgaacagcctgaaacctgaggacacggccatgtattactgt
gcggcggcccgttaccgggggattgggtcccaagtgcggtggactgactttatttactgg
ggccaggggacccaggtcaccgtctcc

Data Source:

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