abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVQLVESGGGSVQAGGSLRLSCAGSGYMYS	1 - 30	30
CDR-H1	SKAMG	31 - 35	5
HFR2	WFRQAPGKEREGVA	36 - 49	14
CDR-H2	IIYTDGYSPYYADSVKG	50 - 66	17
HFR3	RFTISQDNAKNTVYLQMNSLKPEDTAMYYCAA	67 - 98	32
CDR-H3	SKRGPSMGWVPKSASYFGD	99 - 117	19
HFR4	WGQGTQVTVS	118 - 127	10
			127

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLVESGGGSVQAGGSLRLSCAGS-----	1 - 25	25
	AbM	DVQLVESGGGSVQAGGSLRLSCAGS-----	1 - 25	25
	Kabat	DVQLVESGGGSVQAGGSLRLSCAGSGYMYS	1 - 30	30
	Contact	DVQLVESGGGSVQAGGSLRLSCAGSGYMY-	1 - 29	29
	IMGT	DVQLVESGGGSVQAGGSLRLSCAGS-----	1 - 25	25
CDR-H1	Chothia	GYMYSSK---	26 - 32	7
	AbM	GYMYSSKAMG	26 - 35	10
	Kabat	-----SKAMG	31 - 35	5
	Contact	----SSKAMG	30 - 35	6
	IMGT	GYMYSSKA--	26 - 33	8
HFR2	Chothia	AMGWFRQAPGKEREGVAII	33 - 51	19
	AbM	---WFRQAPGKEREGVA--	36 - 49	14
	Kabat	---WFRQAPGKEREGVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVAI-	34 - 50	17
CDR-H2	Chothia	-----YTDGYS---------	52 - 57	6
	AbM	---IIYTDGYSPY-------	50 - 59	10
	Kabat	---IIYTDGYSPYYADSVKG	50 - 66	17
	Contact	GVAIIYTDGYSPY-------	47 - 59	13
	IMGT	----IYTDGYSP--------	51 - 58	8
HFR3	Chothia	PYYADSVKGRFTISQDNAKNTVYLQMNSLKPEDTAMYYCAA	58 - 98	41
	AbM	--YADSVKGRFTISQDNAKNTVYLQMNSLKPEDTAMYYCAA	60 - 98	39
	Kabat	---------RFTISQDNAKNTVYLQMNSLKPEDTAMYYCAA	67 - 98	32
	Contact	--YADSVKGRFTISQDNAKNTVYLQMNSLKPEDTAMYYC--	60 - 96	37
	IMGT	-YYADSVKGRFTISQDNAKNTVYLQMNSLKPEDTAMYYC--	59 - 96	38
CDR-H3	Chothia	--SKRGPSMGWVPKSASYFGD	99 - 117	19
	AbM	--SKRGPSMGWVPKSASYFGD	99 - 117	19
	Kabat	--SKRGPSMGWVPKSASYFGD	99 - 117	19
	Contact	AASKRGPSMGWVPKSASYFG-	97 - 116	20
	IMGT	AASKRGPSMGWVPKSASYFGD	97 - 117	21
HFR4	Chothia	-WGQGTQVTVS	118 - 127	10
	AbM	-WGQGTQVTVS	118 - 127	10
	Kabat	-WGQGTQVTVS	118 - 127	10
	Contact	DWGQGTQVTVS	117 - 127	11
	IMGT	-WGQGTQVTVS	118 - 127	10

Accession & Annotations

Accession	AID18522.1
Source	abYsis-EMBL-IG KJ662673 Submitted 23-JUN-2014 Updated 23-JUN-2014
Name	immunoglobulin heavy chain variable region
Organism	Camelus bactrianus
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Yang S., Yin S., Shang Y., Liu X. Submitted (02-APR-2014) to the INSDC. State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, 1 Xujiaping, Yanchangpu, Chengguan District, Lanzhou, Gansu 730046, China Yang S., Yin S., Shang Y., Liu X. 'Selection and identification of single-domain antibody fragment against capsid protein of porcine circovirus type 2 (PCV2) from C. bactrianus' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DVQLVESGGGSVQAGGSLRLSCAGSGYMYSSKAMGWFRQAPGKEREGVAIIYTDGYSPYY
ADSVKGRFTISQDNAKNTVYLQMNSLKPEDTAMYYCAASKRGPSMGWVPKSASYFGDWGQ
GTQVTVS

DNA Sequence:

gatgtgcagctggtggagtctggaggaggctcggtgcaggctggagggtctctgagactc
tcctgtgcaggctctggatacatgtacagtagcaaagccatgggctggttccgccaggct
ccagggaaggagcgcgagggggtcgcaattatttatactgatggttatagcccatactat
gccgactccgtgaagggccgattcaccatctcccaagacaacgccaagaacacggtttat
ctgcaaatgaacagcctgaaacctgaggacactgccatgtactactgtgcggcgagcaaa
cgagggccttctatgggttgggtacccaaatccgcctcttactttggtgactggggccag
gggacccaggtcaccgtctcc

Data Source:

Alignment settings:

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