abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLKLSCAASGGAYR	1 - 30	30
CDR-H1	NACMG	31 - 35	5
HFR2	WFRQAPGKEREGVA	36 - 49	14
CDR-H2	IINSVDTTYYADPVKG	50 - 65	16
HFR3	RFTISRDNAKSTVYLLMNSLKPEDTAIYYCAQ	66 - 97	32
CDR-H3	VARVVCPGDKLGASGYNY	98 - 115	18
HFR4	WGQGTQVTVSS	116 - 126	11
			126

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLKLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLKLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLKLSCAASGGAYR	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLKLSCAASGGAY-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLKLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GGAYRNA---	26 - 32	7
	AbM	GGAYRNACMG	26 - 35	10
	Kabat	-----NACMG	31 - 35	5
	Contact	----RNACMG	30 - 35	6
	IMGT	GGAYRNAC--	26 - 33	8
HFR2	Chothia	CMGWFRQAPGKEREGVAII	33 - 51	19
	AbM	---WFRQAPGKEREGVA--	36 - 49	14
	Kabat	---WFRQAPGKEREGVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVAI-	34 - 50	17
CDR-H2	Chothia	-----NSVDT---------	52 - 56	5
	AbM	---IINSVDTTY-------	50 - 58	9
	Kabat	---IINSVDTTYYADPVKG	50 - 65	16
	Contact	GVAIINSVDTTY-------	47 - 58	12
	IMGT	----INSVDTT--------	51 - 57	7
HFR3	Chothia	TYYADPVKGRFTISRDNAKSTVYLLMNSLKPEDTAIYYCAQ	57 - 97	41
	AbM	--YADPVKGRFTISRDNAKSTVYLLMNSLKPEDTAIYYCAQ	59 - 97	39
	Kabat	---------RFTISRDNAKSTVYLLMNSLKPEDTAIYYCAQ	66 - 97	32
	Contact	--YADPVKGRFTISRDNAKSTVYLLMNSLKPEDTAIYYC--	59 - 95	37
	IMGT	-YYADPVKGRFTISRDNAKSTVYLLMNSLKPEDTAIYYC--	58 - 95	38
CDR-H3	Chothia	--VARVVCPGDKLGASGYNY	98 - 115	18
	AbM	--VARVVCPGDKLGASGYNY	98 - 115	18
	Kabat	--VARVVCPGDKLGASGYNY	98 - 115	18
	Contact	AQVARVVCPGDKLGASGYN-	96 - 114	19
	IMGT	AQVARVVCPGDKLGASGYNY	96 - 115	20
HFR4	Chothia	-WGQGTQVTVSS	116 - 126	11
	AbM	-WGQGTQVTVSS	116 - 126	11
	Kabat	-WGQGTQVTVSS	116 - 126	11
	Contact	YWGQGTQVTVSS	115 - 126	12
	IMGT	-WGQGTQVTVSS	116 - 126	11

Accession & Annotations

Accession	AIF28002.1
Source	abYsis-EMBL-IG KJ732835 Submitted 17-JUL-2014 Updated 17-JUL-2014
Name	anti-sfGFP immunoglobulin heavy chain
Clone	NbsfGFP01
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Twair A., Al-Okla S., Zarkawi M., Abbady A.Q. 'Characterization of camel nanobodies specific for superfolder GFP fusion proteins' Mol. Biol. Rep. 41(10):6887-6898(2014). Abbady A.Q. Submitted (18-APR-2014) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLKLSCAASGGAYRNACMGWFRQAPGKEREGVAIINSVDTTYYA
DPVKGRFTISRDNAKSTVYLLMNSLKPEDTAIYYCAQVARVVCPGDKLGASGYNYWGQGT
QVTVSS

DNA Sequence:

caggtgcagctgcaggagtctgggggaggctcggtgcaggctggagggtctctgaagctc
tcctgtgcagccagtggaggcgcctacagaaacgcctgtatgggctggttccgccaggct
ccggggaaggagcgtgagggtgtcgcgattattaatagtgttgatacaacatactacgcc
gaccccgtgaagggccgattcaccatctcccgcgacaacgccaagagcacggtgtatctg
ctaatgaacagcctgaaacctgaagacacggccatctattactgcgcgcaggtcgcccga
gtcgtgtgccccggcgataagttgggagcctccggctataactactggggccaggggacc
caggtcaccgtctcctca

Data Source:

Alignment settings:

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