abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLRLSCAASGPTYS	1 - 30	30
CDR-H1	SYFMA	31 - 35	5
HFR2	WFRQAPGMEREGVA	36 - 49	14
CDR-H2	ASSYDGSTTLYADSVKG	50 - 66	17
HFR3	RFTISQGNAKNTKFLLLNNLEPEDTAIYYCAL	67 - 98	32
CDR-H3	RRRGWSNTSGWKQPGWYDY	99 - 117	19
HFR4	WGQGTQVTVSS	118 - 128	11
			128

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLRLSCAASGPTYS	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLRLSCAASGPTY-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GPTYSSY---	26 - 32	7
	AbM	GPTYSSYFMA	26 - 35	10
	Kabat	-----SYFMA	31 - 35	5
	Contact	----SSYFMA	30 - 35	6
	IMGT	GPTYSSYF--	26 - 33	8
HFR2	Chothia	FMAWFRQAPGMEREGVAAS	33 - 51	19
	AbM	---WFRQAPGMEREGVA--	36 - 49	14
	Kabat	---WFRQAPGMEREGVA--	36 - 49	14
	Contact	---WFRQAPGMERE-----	36 - 46	11
	IMGT	-MAWFRQAPGMEREGVAA-	34 - 50	17
CDR-H2	Chothia	-----SYDGST---------	52 - 57	6
	AbM	---ASSYDGSTTL-------	50 - 59	10
	Kabat	---ASSYDGSTTLYADSVKG	50 - 66	17
	Contact	GVAASSYDGSTTL-------	47 - 59	13
	IMGT	----SSYDGSTT--------	51 - 58	8
HFR3	Chothia	TLYADSVKGRFTISQGNAKNTKFLLLNNLEPEDTAIYYCAL	58 - 98	41
	AbM	--YADSVKGRFTISQGNAKNTKFLLLNNLEPEDTAIYYCAL	60 - 98	39
	Kabat	---------RFTISQGNAKNTKFLLLNNLEPEDTAIYYCAL	67 - 98	32
	Contact	--YADSVKGRFTISQGNAKNTKFLLLNNLEPEDTAIYYC--	60 - 96	37
	IMGT	-LYADSVKGRFTISQGNAKNTKFLLLNNLEPEDTAIYYC--	59 - 96	38
CDR-H3	Chothia	--RRRGWSNTSGWKQPGWYDY	99 - 117	19
	AbM	--RRRGWSNTSGWKQPGWYDY	99 - 117	19
	Kabat	--RRRGWSNTSGWKQPGWYDY	99 - 117	19
	Contact	ALRRRGWSNTSGWKQPGWYD-	97 - 116	20
	IMGT	ALRRRGWSNTSGWKQPGWYDY	97 - 117	21
HFR4	Chothia	-WGQGTQVTVSS	118 - 128	11
	AbM	-WGQGTQVTVSS	118 - 128	11
	Kabat	-WGQGTQVTVSS	118 - 128	11
	Contact	YWGQGTQVTVSS	117 - 128	12
	IMGT	-WGQGTQVTVSS	118 - 128	11

Accession & Annotations

Accession	AIF28003.1
Source	abYsis-EMBL-IG KJ732836 Submitted 17-JUL-2014 Updated 17-JUL-2014
Name	anti-sfGFP immunoglobulin heavy chain
Clone	NbsfGFP02
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Twair A., Al-Okla S., Zarkawi M., Abbady A.Q. 'Characterization of camel nanobodies specific for superfolder GFP fusion proteins' Mol. Biol. Rep. 41(10):6887-6898(2014). Abbady A.Q. Submitted (18-APR-2014) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLRLSCAASGPTYSSYFMAWFRQAPGMEREGVAASSYDGSTTLY
ADSVKGRFTISQGNAKNTKFLLLNNLEPEDTAIYYCALRRRGWSNTSGWKQPGWYDYWGQ
GTQVTVSS

DNA Sequence:

caggtgcagctgcaggagtctgggggaggctcggtgcaggctggagggtctctgagactc
tcctgtgcagcctctggacctacctacagtagctacttcatggcctggttccgccaggcg
ccagggatggagcgtgagggggtcgcagctagtagttatgatggtagtaccacattgtac
gccgactccgtgaagggccgattcaccatttcccaaggcaacgccaagaacacgaagttt
ctgttgctgaacaacctggaacctgaggacacggccatttactattgtgcgctccgtcgt
cggggatggtcgaatacgtcaggttggaagcaaccgggatggtatgactactggggccag
gggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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