abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLRLSCADSGYTFS	1 - 30	30
CDR-H1	DYCMG	31 - 35	5
HFR2	WFRQAPGKEREGVA	36 - 49	14
CDR-H2	IISNGGLITRYADSVKG	50 - 66	17
HFR3	RFTVSRDNAKNTLYLEMNSLKPEDTATYFCAK	67 - 98	32
CDR-H3	GSYTCNPDRWSQVSDYKY	99 - 116	18
HFR4	GGQGTQVTVSS	117 - 127	11
			127

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLRLSCADS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLRLSCADS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLRLSCADSGYTFS	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLRLSCADSGYTF-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLRLSCADS-----	1 - 25	25
CDR-H1	Chothia	GYTFSDY---	26 - 32	7
	AbM	GYTFSDYCMG	26 - 35	10
	Kabat	-----DYCMG	31 - 35	5
	Contact	----SDYCMG	30 - 35	6
	IMGT	GYTFSDYC--	26 - 33	8
HFR2	Chothia	CMGWFRQAPGKEREGVAII	33 - 51	19
	AbM	---WFRQAPGKEREGVA--	36 - 49	14
	Kabat	---WFRQAPGKEREGVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVAI-	34 - 50	17
CDR-H2	Chothia	-----SNGGLI---------	52 - 57	6
	AbM	---IISNGGLITR-------	50 - 59	10
	Kabat	---IISNGGLITRYADSVKG	50 - 66	17
	Contact	GVAIISNGGLITR-------	47 - 59	13
	IMGT	----ISNGGLIT--------	51 - 58	8
HFR3	Chothia	TRYADSVKGRFTVSRDNAKNTLYLEMNSLKPEDTATYFCAK	58 - 98	41
	AbM	--YADSVKGRFTVSRDNAKNTLYLEMNSLKPEDTATYFCAK	60 - 98	39
	Kabat	---------RFTVSRDNAKNTLYLEMNSLKPEDTATYFCAK	67 - 98	32
	Contact	--YADSVKGRFTVSRDNAKNTLYLEMNSLKPEDTATYFC--	60 - 96	37
	IMGT	-RYADSVKGRFTVSRDNAKNTLYLEMNSLKPEDTATYFC--	59 - 96	38
CDR-H3	Chothia	--GSYTCNPDRWSQVSDYKY	99 - 116	18
	AbM	--GSYTCNPDRWSQVSDYKY	99 - 116	18
	Kabat	--GSYTCNPDRWSQVSDYKY	99 - 116	18
	Contact	AKGSYTCNPDRWSQVSDYK-	97 - 115	19
	IMGT	AKGSYTCNPDRWSQVSDYKY	97 - 116	20
HFR4	Chothia	-GGQGTQVTVSS	117 - 127	11
	AbM	-GGQGTQVTVSS	117 - 127	11
	Kabat	-GGQGTQVTVSS	117 - 127	11
	Contact	YGGQGTQVTVSS	116 - 127	12
	IMGT	-GGQGTQVTVSS	117 - 127	11

Accession & Annotations

Accession	AIF28006.1
Source	abYsis-EMBL-IG KJ732839 Submitted 17-JUL-2014 Updated 17-JUL-2014
Name	anti-sfGFP immunoglobulin heavy chain
Clone	NbsfGFP06
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Twair A., Al-Okla S., Zarkawi M., Abbady A.Q. 'Characterization of camel nanobodies specific for superfolder GFP fusion proteins' Mol. Biol. Rep. 41(10):6887-6898(2014). Abbady A.Q. Submitted (18-APR-2014) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLRLSCADSGYTFSDYCMGWFRQAPGKEREGVAIISNGGLITRY
ADSVKGRFTVSRDNAKNTLYLEMNSLKPEDTATYFCAKGSYTCNPDRWSQVSDYKYGGQG
TQVTVSS

DNA Sequence:

caggtgcagctgcaggagtctgggggaggctcggtgcaggctggagggtctctgagactc
tcctgtgcagattctggctacaccttcagtgactactgcatgggctggttccgccaggct
ccagggaaggagcgtgagggggtcgcaattatttctaatggtggtcttattacacgctac
gccgactctgtgaagggccgattcaccgtctcccgagacaacgccaagaacacactgtat
ctggagatgaacagcttgaaacctgaggacacggccacctacttctgtgcgaaggggtca
tacacttgtaaccctgaccgctggtcacaggtgtcggattataagtacgggggccagggg
acccaggtcaccgtctcctca

Data Source:

Alignment settings:

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