abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLRLSCESSGMTFS	1 - 30	30
CDR-H1	VYNLG	31 - 35	5
HFR2	WLRQAPGQECELVS	36 - 49	14
CDR-H2	TITRDGSTDYADSMKG	50 - 65	16
HFR3	RFTISRDNAKNTMYLQMTSLKPDDTAVYYCAA	66 - 97	32
CDR-H3	GVGVVDCT	98 - 105	8
HFR4	EGQGTQVTVSS	106 - 116	11
			116

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLRLSCESS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLRLSCESS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLRLSCESSGMTFS	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLRLSCESSGMTF-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLRLSCESS-----	1 - 25	25
CDR-H1	Chothia	GMTFSVY---	26 - 32	7
	AbM	GMTFSVYNLG	26 - 35	10
	Kabat	-----VYNLG	31 - 35	5
	Contact	----SVYNLG	30 - 35	6
	IMGT	GMTFSVYN--	26 - 33	8
HFR2	Chothia	NLGWLRQAPGQECELVSTI	33 - 51	19
	AbM	---WLRQAPGQECELVS--	36 - 49	14
	Kabat	---WLRQAPGQECELVS--	36 - 49	14
	Contact	---WLRQAPGQECE-----	36 - 46	11
	IMGT	-LGWLRQAPGQECELVST-	34 - 50	17
CDR-H2	Chothia	-----TRDGS---------	52 - 56	5
	AbM	---TITRDGSTD-------	50 - 58	9
	Kabat	---TITRDGSTDYADSMKG	50 - 65	16
	Contact	LVSTITRDGSTD-------	47 - 58	12
	IMGT	----ITRDGST--------	51 - 57	7
HFR3	Chothia	TDYADSMKGRFTISRDNAKNTMYLQMTSLKPDDTAVYYCAA	57 - 97	41
	AbM	--YADSMKGRFTISRDNAKNTMYLQMTSLKPDDTAVYYCAA	59 - 97	39
	Kabat	---------RFTISRDNAKNTMYLQMTSLKPDDTAVYYCAA	66 - 97	32
	Contact	--YADSMKGRFTISRDNAKNTMYLQMTSLKPDDTAVYYC--	59 - 95	37
	IMGT	-DYADSMKGRFTISRDNAKNTMYLQMTSLKPDDTAVYYC--	58 - 95	38
CDR-H3	Chothia	--GVGVVDCT	98 - 105	8
	AbM	--GVGVVDCT	98 - 105	8
	Kabat	--GVGVVDCT	98 - 105	8
	Contact	AAGVGVVDC-	96 - 104	9
	IMGT	AAGVGVVDCT	96 - 105	10
HFR4	Chothia	-EGQGTQVTVSS	106 - 116	11
	AbM	-EGQGTQVTVSS	106 - 116	11
	Kabat	-EGQGTQVTVSS	106 - 116	11
	Contact	TEGQGTQVTVSS	105 - 116	12
	IMGT	-EGQGTQVTVSS	106 - 116	11

Accession & Annotations

Accession	AIF28007.1
Source	abYsis-EMBL-IG KJ732840 Submitted 17-JUL-2014 Updated 17-JUL-2014
Name	anti-sfGFP immunoglobulin heavy chain
Clone	NbsfGFP07
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Twair A., Al-Okla S., Zarkawi M., Abbady A.Q. 'Characterization of camel nanobodies specific for superfolder GFP fusion proteins' Mol. Biol. Rep. 41(10):6887-6898(2014). Abbady A.Q. Submitted (18-APR-2014) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLRLSCESSGMTFSVYNLGWLRQAPGQECELVSTITRDGSTDYA
DSMKGRFTISRDNAKNTMYLQMTSLKPDDTAVYYCAAGVGVVDCTEGQGTQVTVSS

DNA Sequence:

caggtgcagctgcaggagtctggaggaggctcggtgcaggctggagggtctctgagactc
tcctgtgagtcctctggtatgaccttcagtgtttataacctgggctggctccgccaggct
ccagggcaggagtgcgaactggtctcaactattactcgtgatggtagtacagactatgcc
gactccatgaagggacgattcaccatctcccgagacaacgccaagaacacgatgtatctg
caaatgaccagcctgaaaccggacgacacggccgtgtattactgtgcggcaggtgttggg
gtggtagattgcacggagggccaggggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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