abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQVGGSLRLSCVYSGNHDS	1 - 30	30
CDR-H1	FQTMG	31 - 35	5
HFR2	WFRQAPGKEREGVA	36 - 49	14
CDR-H2	TINYVGLTFVRASVRG	50 - 65	16
HFR3	RFTISQDDAMKTMYLQMDSLKAEDTGVYYCAA	66 - 97	32
CDR-H3	KGVADRDFTNFDY	98 - 110	13
HFR4	WGQGTQVTVSS	111 - 121	11
			121

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQVGGSLRLSCVYS-----	1 - 25	25
	AbM	QVQLQESGGGSVQVGGSLRLSCVYS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQVGGSLRLSCVYSGNHDS	1 - 30	30
	Contact	QVQLQESGGGSVQVGGSLRLSCVYSGNHD-	1 - 29	29
	IMGT	QVQLQESGGGSVQVGGSLRLSCVYS-----	1 - 25	25
CDR-H1	Chothia	GNHDSFQ---	26 - 32	7
	AbM	GNHDSFQTMG	26 - 35	10
	Kabat	-----FQTMG	31 - 35	5
	Contact	----SFQTMG	30 - 35	6
	IMGT	GNHDSFQT--	26 - 33	8
HFR2	Chothia	TMGWFRQAPGKEREGVATI	33 - 51	19
	AbM	---WFRQAPGKEREGVA--	36 - 49	14
	Kabat	---WFRQAPGKEREGVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVAT-	34 - 50	17
CDR-H2	Chothia	-----NYVGL---------	52 - 56	5
	AbM	---TINYVGLTF-------	50 - 58	9
	Kabat	---TINYVGLTFVRASVRG	50 - 65	16
	Contact	GVATINYVGLTF-------	47 - 58	12
	IMGT	----INYVGLT--------	51 - 57	7
HFR3	Chothia	TFVRASVRGRFTISQDDAMKTMYLQMDSLKAEDTGVYYCAA	57 - 97	41
	AbM	--VRASVRGRFTISQDDAMKTMYLQMDSLKAEDTGVYYCAA	59 - 97	39
	Kabat	---------RFTISQDDAMKTMYLQMDSLKAEDTGVYYCAA	66 - 97	32
	Contact	--VRASVRGRFTISQDDAMKTMYLQMDSLKAEDTGVYYC--	59 - 95	37
	IMGT	-FVRASVRGRFTISQDDAMKTMYLQMDSLKAEDTGVYYC--	58 - 95	38
CDR-H3	Chothia	--KGVADRDFTNFDY	98 - 110	13
	AbM	--KGVADRDFTNFDY	98 - 110	13
	Kabat	--KGVADRDFTNFDY	98 - 110	13
	Contact	AAKGVADRDFTNFD-	96 - 109	14
	IMGT	AAKGVADRDFTNFDY	96 - 110	15
HFR4	Chothia	-WGQGTQVTVSS	111 - 121	11
	AbM	-WGQGTQVTVSS	111 - 121	11
	Kabat	-WGQGTQVTVSS	111 - 121	11
	Contact	YWGQGTQVTVSS	110 - 121	12
	IMGT	-WGQGTQVTVSS	111 - 121	11

Accession & Annotations

Accession	AIF28012.1
Source	abYsis-EMBL-IG KJ732845 Submitted 17-JUL-2014 Updated 17-JUL-2014
Name	anti-human growth hormone immunoglobulin heavy chain variable region
Clone	NbGH04
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Abbady A.Q. Submitted (18-APR-2014) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQVGGSLRLSCVYSGNHDSFQTMGWFRQAPGKEREGVATINYVGLTFVR
ASVRGRFTISQDDAMKTMYLQMDSLKAEDTGVYYCAAKGVADRDFTNFDYWGQGTQVTVS
S

DNA Sequence:

caggtgcagctgcaggagtctgggggaggatcggtgcaggttggagggtctctgagactc
tcttgtgtatactctggaaaccatgatagtttccaaaccatgggctggttccgccaggct
ccagggaaggagcgcgagggggtcgcgaccattaattatgttggtttgacattcgttcgc
gcatccgtgaggggccgattcaccatctcccaagacgacgccatgaagacaatgtatctg
caaatggacagcctgaaggctgaggacactggcgtgtactactgtgcagctaaaggagtt
gccgatagagacttcacaaactttgattactggggccaggggactcaggtcaccgtctcc
tca

Data Source:

Alignment settings:

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