abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGESLRLSCTVPGYTRN	1 - 30	30
CDR-H1	GCVLN	31 - 35	5
HFR2	WYRLATGKPREWVS	36 - 49	14
CDR-H2	SIDTDGNTMYRTPVKG	50 - 65	16
HFR3	RFTISQDSAKDTAFLQMNSLKVEDTAMYFCRT	66 - 97	32
CDR-H3	TGTTRWCRPSD	98 - 108	11
HFR4	WGQGTQVTVSS	109 - 119	11
			119

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGESLRLSCTVP-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGESLRLSCTVP-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGESLRLSCTVPGYTRN	1 - 30	30
	Contact	QVQLQESGGGSVQAGESLRLSCTVPGYTR-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGESLRLSCTVP-----	1 - 25	25
CDR-H1	Chothia	GYTRNGC---	26 - 32	7
	AbM	GYTRNGCVLN	26 - 35	10
	Kabat	-----GCVLN	31 - 35	5
	Contact	----NGCVLN	30 - 35	6
	IMGT	GYTRNGCV--	26 - 33	8
HFR2	Chothia	VLNWYRLATGKPREWVSSI	33 - 51	19
	AbM	---WYRLATGKPREWVS--	36 - 49	14
	Kabat	---WYRLATGKPREWVS--	36 - 49	14
	Contact	---WYRLATGKPRE-----	36 - 46	11
	IMGT	-LNWYRLATGKPREWVSS-	34 - 50	17
CDR-H2	Chothia	-----DTDGN---------	52 - 56	5
	AbM	---SIDTDGNTM-------	50 - 58	9
	Kabat	---SIDTDGNTMYRTPVKG	50 - 65	16
	Contact	WVSSIDTDGNTM-------	47 - 58	12
	IMGT	----IDTDGNT--------	51 - 57	7
HFR3	Chothia	TMYRTPVKGRFTISQDSAKDTAFLQMNSLKVEDTAMYFCRT	57 - 97	41
	AbM	--YRTPVKGRFTISQDSAKDTAFLQMNSLKVEDTAMYFCRT	59 - 97	39
	Kabat	---------RFTISQDSAKDTAFLQMNSLKVEDTAMYFCRT	66 - 97	32
	Contact	--YRTPVKGRFTISQDSAKDTAFLQMNSLKVEDTAMYFC--	59 - 95	37
	IMGT	-MYRTPVKGRFTISQDSAKDTAFLQMNSLKVEDTAMYFC--	58 - 95	38
CDR-H3	Chothia	--TGTTRWCRPSD	98 - 108	11
	AbM	--TGTTRWCRPSD	98 - 108	11
	Kabat	--TGTTRWCRPSD	98 - 108	11
	Contact	RTTGTTRWCRPS-	96 - 107	12
	IMGT	RTTGTTRWCRPSD	96 - 108	13
HFR4	Chothia	-WGQGTQVTVSS	109 - 119	11
	AbM	-WGQGTQVTVSS	109 - 119	11
	Kabat	-WGQGTQVTVSS	109 - 119	11
	Contact	DWGQGTQVTVSS	108 - 119	12
	IMGT	-WGQGTQVTVSS	109 - 119	11

Accession & Annotations

Accession	AIF28013.1
Source	abYsis-EMBL-IG KJ732846 Submitted 17-JUL-2014 Updated 17-JUL-2014
Name	anti-human growth hormone immunoglobulin heavy chain variable region
Clone	NbGH06
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Abbady A.Q. Submitted (18-APR-2014) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGESLRLSCTVPGYTRNGCVLNWYRLATGKPREWVSSIDTDGNTMYR
TPVKGRFTISQDSAKDTAFLQMNSLKVEDTAMYFCRTTGTTRWCRPSDWGQGTQVTVSS

DNA Sequence:

caggtgcagctgcaggagtctggaggaggctcggtgcaggccggggagtctctgagactc
tcctgcacagtccctggatacaccagaaatgggtgtgtgctgaactggtaccgcctggct
acagggaagccgcgcgagtgggtctcatctatagacactgatggtaacacaatgtataga
acccccgtgaagggccgattcaccatctcccaagacagcgccaaggacacggcgtttctg
caaatgaacagcctaaaagttgaagatacggccatgtatttttgtagaactactggtacg
actcggtggtgccgtccaagtgactggggccaggggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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