abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLKLSCAASGYIAS	1 - 30	30
CDR-H1	GCGMGGMA	31 - 38	8
HFR2	WYRQAPGKERELVS	39 - 52	14
CDR-H2	TISRDGIRYIGAVKG	53 - 67	15
HFR3	RFTISRDSAKNTLYLQMSSLKTEDTGVYYCAA	68 - 99	32
CDR-H3	CRRSIDDYTY	100 - 109	10
HFR4	WGQGTQVTVSS	110 - 120	11
			120

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLKLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLKLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLKLSCAASGYIAS	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLKLSCAASGYIA-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLKLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GYIASGCGMG---	26 - 35	10
	AbM	GYIASGCGMGGMA	26 - 38	13
	Kabat	-----GCGMGGMA	31 - 38	8
	Contact	----SGCGMGGMA	30 - 38	9
	IMGT	GYIASGCGMGG--	26 - 36	11
HFR2	Chothia	GMAWYRQAPGKERELVSTI	36 - 54	19
	AbM	---WYRQAPGKERELVS--	39 - 52	14
	Kabat	---WYRQAPGKERELVS--	39 - 52	14
	Contact	---WYRQAPGKERE-----	39 - 49	11
	IMGT	-MAWYRQAPGKERELVST-	37 - 53	17
CDR-H2	Chothia	-----SRDG---------	55 - 58	4
	AbM	---TISRDGIR-------	53 - 60	8
	Kabat	---TISRDGIRYIGAVKG	53 - 67	15
	Contact	LVSTISRDGIR-------	50 - 60	11
	IMGT	----ISRDGI--------	54 - 59	6
HFR3	Chothia	IRYIGAVKGRFTISRDSAKNTLYLQMSSLKTEDTGVYYCAA	59 - 99	41
	AbM	--YIGAVKGRFTISRDSAKNTLYLQMSSLKTEDTGVYYCAA	61 - 99	39
	Kabat	---------RFTISRDSAKNTLYLQMSSLKTEDTGVYYCAA	68 - 99	32
	Contact	--YIGAVKGRFTISRDSAKNTLYLQMSSLKTEDTGVYYC--	61 - 97	37
	IMGT	-RYIGAVKGRFTISRDSAKNTLYLQMSSLKTEDTGVYYC--	60 - 97	38
CDR-H3	Chothia	--CRRSIDDYTY	100 - 109	10
	AbM	--CRRSIDDYTY	100 - 109	10
	Kabat	--CRRSIDDYTY	100 - 109	10
	Contact	AACRRSIDDYT-	98 - 108	11
	IMGT	AACRRSIDDYTY	98 - 109	12
HFR4	Chothia	-WGQGTQVTVSS	110 - 120	11
	AbM	-WGQGTQVTVSS	110 - 120	11
	Kabat	-WGQGTQVTVSS	110 - 120	11
	Contact	YWGQGTQVTVSS	109 - 120	12
	IMGT	-WGQGTQVTVSS	110 - 120	11

Accession & Annotations

Accession	ALN98710.1
Source	abYsis-EMBL-IG KT428334 Submitted 23-NOV-2015 Updated 23-JUN-2016
Name	immunoglobulin heavy chain variable region
Organism	Camelus bactrianus
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Liu H., Wang Y., Duan H., Zhang A., Liang C., Gao J., Zhang C., Huang B., Li Q., Li N., Xiao S., Zhou E.M. 'An intracellularly expressed Nsp9-specific nanobody in MARC-145 cells inhibits porcine reproductive and respiratory syndrome virus replication' Vet. Microbiol. 181(3-4):252-260(2015). Liu H., Xiao S., Wang Y., Duan H., Zhou E.-M. Submitted (14-AUG-2015) to the INSDC. College of Veterinary Medicine, Northwest A&F University, Xinong Road 22, Yangling, Shaanxi 712100, China

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLKLSCAASGYIASGCGMGGMAWYRQAPGKERELVSTISRDGIR
YIGAVKGRFTISRDSAKNTLYLQMSSLKTEDTGVYYCAACRRSIDDYTYWGQGTQVTVSS

DNA Sequence:

caggtccaactgcaggagtctgggggaggctcggtgcaggctggagggtctctgaaactc
tcctgtgcagcctctggttacattgctagtggctgcggaatgggcggaatggcctggtac
cgccaggctccagggaaggagcgcgagttggtttcaacgatcagtagagatggtatcagg
tatataggcgccgtgaagggccgattcaccatctcccgagacagcgccaagaacacgctg
tatctgcaaatgtccagcctgaaaactgaggacacgggcgtgtattactgcgcggcctgc
agacgaagtattgatgactacacctactggggccaggggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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